Decellularization and Recellularization Apparatuses and Systems Containing the Same
The invention described herein provides systems and apparatuses for an initialpreparation of an organ or tissue scaffold comprising an extracellular matrix, and subsequent recellularization of the scaffold to ultimately form a resultant artificial organ or tissue incorporating the natural and original extracellular matrix. The techniques and equipment of the invention collectively minimize scaffold collapse, compression or physical damage to the organ as well as afford the advantages of significant maintenance of the initial natural structural and biochemical attributes of the organ or tissue. The invention is particularly useful in organ and tissue transplantation and repair.
TAYLOR DORIS [US]; KREN STEFAN M [US]; ROBERTSON MATTHEW JEFFREY [US]
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