Homologous Recombination in Multipotent Adult Progenitor Cells

The invention relates to methods of altering gene expression by homologous recombination in a multipotent adult progenitor cell (MAPC). In particular, methods of producing a recombinant MAPC, of correcting a genetic defect in a mammal, of providing a functional and/or therapeutic protein to a mammal, and of transforming a MAPC are provided. MAPCs containing an erogenous DNA as well as recombinant MAPCs and their differentiated progeny are also provided.

Attached files:
US 20100285590.jpg

Patents:
US 20,100,285,590

Inventor(s): VERFAILLIE CATHERINE [BE]; LAKSHMIPATHY UMA [US]

Type of Offer: Licensing



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