Immunostimulatory nucleic acid molecules

Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

Patents:
US 7,935,675

Inventor(s): KRIEG ARTHUR M [US]; KLINE JOEL N [US]

Type of Offer: Licensing



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