Immunostimulatory Nucleic Acids

The invention relates to immunostimulatory nucleic acid compositions and methods of using the compositions. The T-rich nucleic acids contain poly T sequences and/or have greater than 25% T nucleotide residues. The TG nucleic acids have TG dinucleotides. The C-rich nucleic acids have at least one poly-C region and/ore greater than 50% c nucleotides. These immunostimulatory nucleic acids function in a similar manner to nucleic acids containing CpG motifs. The invention also encompasses preferred CpG nucleic acids.

Patents:
US 20,090,191,188

Inventor(s): KRIEG ARTHUR M [US]; SCHETTER CHRISTIAN [DE]; VOLLMER JORG [DE]

Type of Offer: Licensing



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