Regulation of Apoptosis By Neural Specific Splice Variants of IG20
Pro-apoptotic signaling caused by down-modulation of KIAA0358 or expression of IG20-SV4 effectively induces spontaneous apoptosis and sensitization to TNFa-induced apoptosis in neuroblastoma cells. Methods and composition to enhance cell death in neuroblastoma are provided. Methods and compositions to reduce cell death in neurodegenerative disorders are provided.
WO 2,010,006,239 [MORE INFO
PRABHAKAR BELLUR S [US]; MERIGGIOLI MATTHEW N [US]; LI LIANG CHENG [US]
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