Activated Mesenchymal Stem Cells for the Prevention and Repair of Inflammatory States
Inflammatory cytokines e.g. IFN-? serve as initiating stimuli for MSC immunosuppresive activity in vivo. Other inflammatory cytokines, such as TNF alpha, the molecule hemoxygenase I, and TLR ligation of MSC may also provide such a response.
Patents:WO 2,009,114,860
Inventor(s):
BARTHOLOMEW AMELIA [US]; POLCHERT DAVID [US]; SZILAGYI ERZSEBET [US]
Type of Offer:
Licensing
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