TARGET DNA INTERFERENCE WITH crRNA

The present invention provides methods, systems, and compositions for interfering with the function and/or presence of a target DNA sequence in a eukaryotic cell (e.g., located in vitro or in a subject) using crRNA and CRISPR-associated (cas) proteins or cas encoding nucleic acids. The present invention also relates to a method for interfering with horizontal gene transfer based on the use of clustered, regularly interspaced short palindromic repeat (CRISPR) sequences.

Patents:
US 20,100,076,057

Inventor(s): SONTHEIMER ERIK J [US]; MARRAFFINI LUCIANO A [US]

Type of Offer: Licensing



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