The present invention relates to anti-cancer compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides analogs of the known anti-cancer compound amonafide, and structurally and functionally related compounds, and methods of using such compounds as therapeutic agents to treat a number of conditions associated with hyperproliferation.
HUANG SUI [US]; NORTON JOHN [US]; APPELLA DANIEL [US]; WITSCHI MARK [US]
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