Methods and Compositions for Diagnosis and Treatment of Cancer
The invention relates to an isolated regulatory nucleic acid, comprising a nucleic acid sequence according to SEQ ID NO 2 or a biologically active fragment thereof that can be specifically amplified and detected by a polymerase chain reaction (PCR), to the use thereof as a tumor marker and for sampling substances, in particular prospective reactive agents for inhibiting the nucleic acid, the peptide or the protein, wherein such substances binding thereto are identified using a binding assay and selected according to the function thereof. The invention further relates to a method for verifying myeloid or non-myeloid tumor cells or tumor cell lines, wherein a nucleic acid sequence is specifically amplified and detected using a polymerase chain reaction (PCR), wherein nucleic acid sequences are selected as PCR primers that comprise or are complementary to a nucleic acid sequence according to SEQ ID NO 2 or a biologically active fragment thereof that can be specifically amplified and detected by the polymerase chain reaction (PCR). The invention finally relates to a pharmaceutical composition, to a treatment plan and to a method for inhibiting the proliferation of myeloid or non-myeloid tumor cells by means of the nucleic acid according to the invention.
RELLE MANFRED [DE]; SCHWARTING ANDREAS [DE]
Type of Offer:
« More Chemistry Patents