Conjugates of 19F MR Imaging Tracers for Use in Multi-chromic MRI Imaging

Compositions for producing multi-chromic ("color") magnetic resonance images (MRI). The compositions for use as MRI imaging agents include a magnetic resonance imaging tracer having a signal emitter, such as a 19F imaging tracer (19FIT), conjugated with a magnetic signal modulator, such as a paramagnetic functional group or a paramagnetic ion. The 19FIT and the signal modulator (M) are joined covalently by a chelator such as DOTA, forming a nanometer-sized fluorinated paramagnetic complex 19FIT-DOTA-M. Other signal emitters, such as 31P imaging tracer (31PIT), can also be modulated using this strategy (i.e., 31PIT-DOTA-M) to generate multi-chromic 31P MRI or MRS.

Attached files:
WO 2010056590.jpg

Patents:
WO 2,010,056,590   [MORE INFO]

Inventor(s): YU YIHUA BRUCE [US]; JIANG ZHONG-XING [US]

Type of Offer: Licensing



Next Patent »
« More Biomedical Patents

Share on      


CrowdSell Your Patent