Prognostic Tools to Predict the Efficacy of Drug Treatment Targeting Chromatin DNA Or Enzymes Acting on DNA

Disclosed are methods of predicting cell response to drug-based therapy using both PCR-Stop assays and real time PCR assays. Methods herein may be used for assessment of drug effect, evaluation of regimen suitability for a given patient, and/or for determination of an optimal drug dose. Also provided are isolated oligonucleotide primers such as primers capable of annealing under PCR conditions to a segment of a c-myc locus, where the primers may be used in the disclosed methods. Further disclosed are kits and systems that may be used for predicting a cell response to drug-based therapy.

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Patents:
US 20,100,173,301   [MORE INFO]

Inventor(s): CARRIER FRANCE [US]; NALABOTHULA NARASIMHAROA [US]

Type of Offer: Licensing



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