Methods of Treating a Microbial Infection By Modulating RNase-L Expression And/or Activity

The invention relates to methods and compositions for treating a microbial infection. In the present invention, RNase-L activity has been shown to play an integral role in innate immunity and for defense against invading microbes. The present invention is drawn to exploiting the role of RNase-L in innate immunity for methods of treating a microbial infection. The present invention is also drawn to exploiting the role of RNase-L in innate immunity for methods of treating an immune related disease or disorder.

Attached files:
WO 2009036000.jpg

Patents:
WO 2,009,036,000   [MORE INFO]

Inventor(s): HASSEL BRET A [US]; CROSS ALAN S [US]; LI XIAO-LING [US]; KANG TAE JIN [KR]

Type of Offer: Licensing



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