Cytotoxin Compound and Method of Isolation
The present invention concerns compounds derived from tunicates of the species Synoicum adareanum, as well as to pharmaceutical compositions comprising these compounds and methods of use. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.
US 9,394,270 issued 2016-07-19 [MORE INFO
US 7,625,885 issued 2009-12-01 [MORE INFO
BAKER BILL J [US]; DIYABALANAGE THUSHARA [US]; MCCLINTOCK JAMES B [US]; AMSLER CHARLES D [US]
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