Growth Factor Binding Molecules

Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growth factors and are suitable for treating a subject having tumors or restinosis. In one embodiment a platelet-derived growth factor binding molecule is disclosed that is used to inhibit tumor growth and angiogenesis in solid tumors.

Patents:
US 20,100,210,516

Inventor(s): SEBTI SAID [US]; HAMILTON ANDREW D [US]

Type of Offer: Licensing



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