Enantioselective Ring-opening of Aziridines

A process for the preparation of a nucleophilic addition product of an aziridine and a nucleophile, the process comprising treating the arizidine with the nucleophile in the presence of a biaryl phosphoric acid catalyst.

Patents:
WO 7,799,934 issued 2010-09-21 [MORE INFO]

Inventor(s): ANTILLA JON [US]; ROWLAND EMILY B [US]; ROWLAND GERALD B [US]

Type of Offer: Licensing