The present invention relates, in general, to a formulation suitable for use in inducing anti-HIV-1 antibodies and, in particular, to a formulation comprising a prehairpin intermediate form of HIV-1 envelope gp41 linked to a liposome. The invention also relates to methods of inducing broadly neutralizing anti-HIV-1 antibodies using such a formulation.
ALAM MUNIR [US]; HAYNES BARTON F [US]; HARRISON STEPHEN [US]; CHEN BING [US]
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