Formulation for Inducing Broadly Reactive Neutralizing Anti-HIV Antibodies
The present invention relates in general, to a formulation suitable for use in inducing anti-HIV-1 antibodies, and, in particular, to a formulation comprising Toll Like Receptor (TLR) agonists with HIV-1 gp41 membrane proximal external region (MPER) peptide-liposome conjugates for induction of broadly reactive anti-HIV-1 antibodies. The invention also relates to methods of inducing neutralizing anti-HIV-1 antibodies using such formulations.
WO 2,010,114,628 [MORE INFO
ALAM S MUNIR [US]; HAYNES BARTON F [US]; SEKARAN MOSES D [US]; TOMARAS GEORGIA [US]; SHEN XIAOYING [US]
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