Antidotes for Agonistic Aptamers

The present invention relates, in general, to aptamers and antidotes therefor and, in particular, to aptamers capable of binding to and activating molecules, such as receptors (e.g., the OX40 receptor) and enzymes. The invention further relates to antidotes to such agonistic aptamers. The invention also relates to compositions comprising, and to methods of using, the agonistic aptamers and the antidotes therefor.

Patents:
WO 2,009,045,545

Inventor(s): SULLENGER BRUCE [US]; DOLLINS CLAUDIA [US]; GILBOA ELI [US]

Type of Offer: Licensing



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