Method for Genetic Manipulation of Extremophiles

Provided herein are methods for introducing a polynucleotide into an extremophile, such as Pyrococcus fitriosis, by conjugation with a member of the family Enterobacteriaceae. Also provided are genetically engineered extremophiles, such as Pyrococcus furiosiis, that include an exogenous polynucleotide integrated into genomic DNA.

Attached files:
WO 2009055699.jpg

Patents:
WO 2,009,055,699

Inventor(s): ADAMS MICHAEL W W [US]; YANG FEI [US]; WESTPHELING JANET [US]

Type of Offer: Licensing



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