Using Female Endocrine Hormones to Improve Psoriasis

Background: The most commonly prescribed medications for severe psoriasis are methotrexate and cyclosporine. Both these medications have serious side effects. The next line of treatment includes phototherapy but this is limited by the availability of light boxes in the dermatologist's office. Biologic treatments which include Infliximab and Etanercept are costly, administered by IV or injection and their side effects are not yet well documented. Technology: University of California, Irvine researchers have found the increase in estriol during pregnancy correlates to psoriasis improvement.
Application: Administration of estriol to psoriasis patients may improve their disease state. Estriol would have less long-term toxicity than the currently available oral treatments and would be more affordable and easier to administer than the biologics. Estriol may also be administered in combination with other therapies to treat psoriasis.

Type of Offer: Licensing



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