Drug screening tool for herpes antivirals

Summary Harvard Medical School researchers have developed a genetically modified herpes simplex virus that has utility as a drug screening tool. To develop this tool, Harvard researchers engineered a replication competent herpes virus that contains green fluorescent protein (GFP) fused to a viral replication protein. During replication, this modified protein is transcribed and translated such that its expression can be detected by fluorescence of the GFP. As a result, drug candidates that affect herpes replication or the expression of this protein can be identified by changes in the level of fluorescence.

Applications Antiviral drug screen For Further Information Please Contact the Director of Business Development Alex Szidon Email: [email protected] Telephone: (617) 495-3067

Inventor(s): Knipe, David M.

Type of Offer: Licensing



Next Patent »
« More Pharmaceutical Patents

Share on      


CrowdSell Your Patent