Animal Model for Benign Prostate Hyperplasia

Summary The invention provides transgenic mouse models of benign prostate hyperplasia. These animals are useful in toxicity screens, as well as in assays aimed at the development of drugs to prevent prostate hyperplasia in mammals, including humans.

References:

Muller et al., 1990, "The int-2 gene product acts as an epithelial growth factor in transgenic mice", EMBO J. 9(3): 907-13.

Tutrone et al., 1993, "Benign prostatic hyperplasia in a transgenic mouse: a new hormonally sensitive investigatory model", J. Urol. 149(3): 633-9.

This technology is protected by U.S. Patent No. 5,175,383, which is available for field-exclusive or non-exclusive license.

Applications Animal model; drug development. For Further Information Please Contact the Director of Business Development Alex Szidon Email: [email protected] Telephone: (617) 495-3067

Inventor(s): Leder, Philip

Type of Offer: Licensing



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