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Having a laptop computer working both as a tablet and as a normal laptop faces challenge of how to respectively orientate its display. When working as a tablet, display of laptop computer has to be swung 180 degree from folded position to face up position. Drawback of working such way is to leave ke...
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Provided herein is a method for the synthesis and the integration of ZnO nanowires and nanocrystalline diamond as a novel hybrid material useful in next generation MEMS/NEMS devices. As diamond can provide a highly stable surface for applications in the harsh environments, realization of such hybrid...
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A process for producing a natural rubber nanocomposite containing exfoliated organically modified montmorillonite and maleic anhydride grafted elastomer in a dispersion of natural rubber and reinforcing filler/inert filler wherein the cured nanocomposite has improved mechanical properties compared t...
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Metadichol®*(anagram METHODICAL) is a product produced from the waste of our agricultural industry and is present in small amounts in our foods we consume on a daily basis as most of it is lost in our food processing.
We suffer from diseases because our immune system gets weakened over time and l...
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Detection techniques currently used in scanning force microscopy impose limitations on the geometrical dimensions of the probes and, as a consequence, on their force sensitivity and temporal response. The University of Bristol invention is a scanning probe microscopy system based on a probe detectio...
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This application provides nanostructure-enhanced stereo-electrodes. The application also provides novel ways to manufacture nanostructure-enhanced electrodes. In some embodiments, the invention also provides methods of use for devices equipped with the nanostructure-enhanced stereo-electrodes....
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This invention presents microstructures enhanced with nanopillars. The invention also provides ways for manufacturing nanopillar-enhanced microstructures. In some embodiments, the invention also provides methods of use for the nanopillar-enhanced microstructures....
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Methods for measuring environmental parameters using chemical recording are provided. In some embodiments, the methods include generating a polymer comprising an ordered series of chemical units, wherein the position and number of each chemical unit in the polymer is indicative of a reading of the e...
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A system for energy upconversion and/or down conversion and a system for producing a photostimulated reaction in a medium. These systems include 1) a nanoparticle configured, upon exposure to a first wavelength ?1 of radiation, to generate a second wavelength ?2 of radiation having a higher energy t...
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A method of synthesis to produce gram-scale quantities of copper nanowires in an aqueous solution, wherein the copper nanowires are dispersed in said solution. Copper nanowires grow from spherical copper nanoparticles within the first 5 minutes of the reaction. Copper nanowires can be collected from...
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A functionalized nanoparticle, having a core, optionally having a shell on at least a portion thereof, wherein the core contains a material that can convert applied X-ray energy into emitted UV energy and wherein the shell, when present, contains a plasmonics active material; wherein the nanoparticl...
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A method of delivering a compound of interest to the lungs of a subject by the intravenous injection of Sertoli cells loaded with a plurality of chitosan nanoparticles coupled with the compound of interest is provided. Testis-derived rat Sertoli cells were pre-loaded with chitosan nanoparticles coup...
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The present invention describes nano-scale fabrication technique used to create a sub-micron wide gap across the center conductor of a coplanar waveguide transmission line configured in a fixed-fixed beam arrangement, resulting in a pair of opposing cantilever beams that comprise an electro-mechanic...
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Drug delivery of resistance reversal agents by polyacrylate nanoparticles for treatment of drug (e.g. chloroquine) resistant malaria. Also provided are drug delivery by polyacrylate nanoparticles of ciprofloxacin for treatment of anthrax....
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The present invention is directed to a device and method of controlling the phase separation of one or a mixture of two or more spider silk proteins, leading to the defined and controllable assembly of the said silk protein(s) to defined morphologies, such as spheres, nano fibrils, threads, etc....
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Producing polymer coated metal containing nanoparticles comprises: preparing a solution of anionic macroinitiators in an aprotic organic solvent; adding at least one anionically polymerizable monomer to the solution; anionically polymerizing at room temperature; adding aliphatic or aromatic sulfide;...
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Producing metal-containing nanoparticles coated with polymers, comprises: preparing a solution of an anionic macro-initiator in an aprotic organic solvent; adding at least one anionic polymerizable monomer to the above solution; anionic polymerizing the above resulting solution at room temperature; ...
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The present invention relates to electrochemical storage devices, such as supercapacitors, batteries, etc., and more particularly to such devices that comprise an electrochemically active coaxial nanowire. The invention particularly concerns such devices in which the coaxial nanowire comprises an in...
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An apparatus, system, and method are provided for a lateral two- terminal nanotube device configured to capture and generate energy, to store electrical energy, and to integrate these functions with power management circuitry. The lateral nanotube device can include a substrate, an anodic oxide mate...
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An in situ approach toward connecting and electrically contacting vertically aligned nanowire arrays using conductive nanoparticles is provided. The utility of the approach is demonstrated by development of a gas sensing device employing the nanowire assembly. Well-aligned, single-crystalline zinc o...
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An apparatus, system, and method are provided for a vertical two-terminal nanotube device configured to capture and generate energy, to store electrical energy, and to integrate these functions with power management circuitry. The vertical nanotube device can include a column disposed in an anodic o...
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Disclosed are fully transparent nanowire transistors having high field-effect mobilities. The fully transparent nanowire transistors disclosed herein include one or more nanowires, a gate dielectric prepared from a transparent inorganic or organic material, and transparent source, drain, and gate co...
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Peptide-amphiphilic compositions capable of self-assembly into useful nanostructures....
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Disclosed herein is energy transfer on multisegmented nanowires via surface plasmon resonance excitation of visible light, such as solar energy, absorbed by metals sensitive to visible light and transferred to metals insensitive to visible light. The nanowires are prepared with controllable gap size...
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There is provided single layer infrared-reflecting films and a method of making the same that provide enhanced reflectivity in an 800 nanometer to 2500 nanometer infrared waveband. The method comprises providing a substrate, depositing onto the substrate a mixture of an oxide matrix material and eit...
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The present invention provides titanium dioxide/single-walled carbon nanotube composites (TiO2/SWCNTs), articles of manufacture, and methods of making and using such composites. In certain embodiments, the present invention provides membrane filters and ceramic articles that are coated with TiO2/SWC...
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Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formatio...
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A method of forming a nanoscale pattern on a substrate surface. In one embodiment, the method includes the steps of providing a substrate having a surface; providing a nanoscale pattern forming device, comprising an elongated cantilever that has a tip portion proximate an end of the elongated cantil...
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A nanoprism having a prismatic silver shell formed about a gold core and a process of forming the same are disclosed. The process includes irradiating a mixture of gold and silver nanoparticles with a narrow band of wavelengths capable of exciting the surface plasmon resonance of the gold....
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Multicomponent nanorods having segments with differing electronic and/or chemical properties are disclosed. The nanorods can be tailored with high precision to create controlled gaps within the nanorods or to produce diodes or resistors, based upon the identities of the components making up the segm...
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Various methods related to the preparation of transparent electrical conductors based on carbon nanotubes having enhanced optical and electrical properties are disclosed. In some embodiments, the methods involve employing carbon nanotubes that have been presorted according to electronic type and/or ...
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A method that combines on-wire-lithography (OWL) nanogaps, an electric field concentrating technique, and surface enhanced Raman spectroscopy (SERS) is disclosed for sensitive detection of analytes with small sample sizes in a chip format....
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Solutions containing oppositely-charged nanoparticles (NPs) deposit "patchy" coatings of alternating charge distribution on various types of materials, including polymers, elastomers, and semiconductors. Surface adsorption of the NPs is driven by cooperative electrostatic interactions and does not r...
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An imaging device. In one embodiment, the imaging device includes a plurality of first electrode strips in parallel to each other along a first direction x, wherein each first electrode strip has an elongated body with a first surface and an opposite, second surface and a thickness n1. The imaging d...
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A method of functionalizing carbon nanotubes with metallic moieties is disclosed. Carbon nanotubes are first associated with one or more binding moieties to provide carbon nanotubes encapsulated by the binding moieties. The encapsulated carbon nanotubes are then contacted with a metal salt or a meta...
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An article of manufacture comprising a nanowire and methods of making the same. In one embodiment, the nanowire includes a Ga-doped trace formed on a surface of an indium oxide layer having a thickness in nano-scale, and wherein the Ga-doped trace is formed with a dimension that has a depth is less ...
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A method of forming a photomask using a microtip is disclosed herein. The method can include depositing a sacrificial pattern on a substrate using a microtip, forming a mask layer over the sacrificial pattern, and removing the sacrificial pattern and a portion of the mask layer disposed on the sacri...
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Methods of forming nanoprisms or nanorods from gold seed particles by adding controlled amounts of iodide ion to the growth solution are disclosed....
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Lithographic and nanolithographic methods that involve patterning a first compound on a substrate surface, exposing non-patterned areas of the substrate surface to a second compound and removing the first compound while leaving the second compound intact. The resulting hole patterns can be used as t...
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A composite cement material is prepared from cement material and carbon nanotubes, wherein the carbon nanotubes are present from about 0.02 wt% to about 0.10 wt % based on weight of cement material. The process for preparing such cement compositions includes sonicating a mixture of a surfactant, wat...
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The present invention relates to nanoconjugates. In particular, the present invention provides nanoconjugates for diagnostic (e.g., imaging), research, and clinical (e.g., targeted treatment) applications....
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The present teachings provide methods for providing populations of singlc- walled carbon nanotubes that are substantially monodisperse in terms of diameter, electronic type, and/or chirality. Also provided are single-walled carbon nanotube populations provided thereby and articles of manufacture inc...
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The invention provides methods to detect cysteine which employ oligonucleotide functionalized nanoparticles....
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Disclosed are nanostructures having nanoprisms and agents, such as diagnostic and/or therapeutic agents. Nanoprisms with a surface plasmon resonance in the near-infrared convert irradiation, such as from a laser into heat selectively to allow the dissociation, such as dehybridization of oligonucleot...
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The present invention is directed to oligonucleotide-modified nanoparticle conjugates and methods of inhibiting bacterial protein production....
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An article of manufacture and methods of making same. In one embodiment, the article of manufacture has a plurality of zinc oxide layers substantially in parallel, wherein each zinc oxide layer has a thickness d1, and a plurality of organic molecule layers substantially in parallel, wherein each org...
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Materials and methods for modulating cellular uptake of functionalized nanoparticles are provided. Also provided are materials and methods for modulating the effectiveness of a therapeutic agent with a functionalized nanoparticle....
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The present teachings provide methods for sorting nanotubes according to their wall number, and optionally further in terms of their diameter, electronic type, and/or chirality. Also provided are highly enriched nanotube populations provided thereby and articles of manufacture including such populat...
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Methods describing the use of nanoparticles modified with binding moieties are provided....
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Disclosed herein are molecule-modified nanoparticles and methods of making and using the same. More specifically, disclosed herein are molecule-modified nanoparticles wherein the molecule is attached to the surface of the nanoparticle via an oligonucleotide. Also disclosed are methods of preparing n...
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The present invention is directed to compositions and methods of localized delivery of a functionalized nanoparticle....
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The present invention is directed to compositions and methods for intracellular delivery of a contrast agent with a functionalized nanoparticle....
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The present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s)....
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The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media....
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The present invention relates to compositions and methods for delivering an oligonucleotide-functionalized nanoparticle....
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The present invention is directed to compositions and methods of use of a functionalized nanoparticle having a catalytic metal deposit....
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Self-erasing inks in which both the printing and self-erasure of color images can be controlled by the dynamic/non-equilibrium aggregation of photoresponsive surface-coated nanoparticles contained in a carrier film are provided. The aggregation is a reversible aggregation that is triggered by a phot...
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The present invention provides various functionalized nanodiamond particles. In particular, the present invention provides soluble complexes of nanodiamond particles and therapeutic agents, for example insoluble therapeutics, anthracycline and/or tetracycline compounds, nucleic acids, proteins, etc....
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Disclosed are methods of lithography using a tip array having a plurality of pens attached to a backing layer, where the tips can comprise a metal, metalloid, and/or semi-conducting material, and the backing layer can comprise an elastomeric polymer. The tip array can be used to perform a lithograph...
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In accordance with an embodiment of the disclosure, a method for forming submicron size nanostructures on a substrate surface includes contacting a substrate with a tip coated with an ink comprising a block copolymer matrix and a nanostructure precursor to form a printed feature comprising the block...
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A method of leveling a polymer pen array includes contacting a pen array with a surface and measuring a total force exerted on the surface by the pen array, the pen array being disposed at a first angle with respect to a first axis of the surface and a second angle with respect to a second axis of t...
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Disclosed are nanoparticles functionalized with an oligonucleotide and a domain, wherein the domain increases cellular uptake of the nanoparticles. The domain is a sequence of nucleobases or phosphate groups, such as a poly thymidine (polyT) sequence or a phosphate polymer (C3 residue) and may be lo...
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The present invention relates to magnetic nanostructures as theranostic agents, which provide dual function as diagnostic and therapeutic agents. In particular, the present invention relates to compositions comprising magnetic nanostructures and their use as targeted therapeutic agents for cancers (...
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The present disclosure is directed to compositions comprising templated nanoconjugates and methods of their use....
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Articles, compositions, kits, and methods relating to nanostructures, including those that can sequester molecules such as cholesterol, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanoparticle core may be surrounded by a...
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The present invention provides monodisperse primary carbon nanoparticles, and methods of preparation and use thereof. In particular, the present invention provides surface-modified monodisperse primary carbon nanoparticles, and methods of preparation and use thereof....
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Polymer-graphite compositions and related methods of using solid-state shear pulverization as can be used to affect one or more physical properties thereof....
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Composites comprising a continuous matrix formed from compounds having a rock salt structure (represented by the structure "MQ") and inclusions comprising chalcogenide compounds having a rock salt structure (represented by the structure "AB") are provided. Composites having the structure MQ-ABC2, wh...
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Modified nanoparticles are disclosed. More specifically, nanoparticles modified with an agent through a triazole linkage are disclosed. Also disclosed are methods of preparing modified nanoparticles and methods of using these modified nanoparticles....
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New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C [beta]-lactamase AmpC. The new compounds improve inhibition by over two-orders of magnitude compared to analogous glycylboronic acids, with Ki values as low as 1 ...
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Direct-write techniques are provided for the high speed (up to millimeter per second) and continuous fabrication of elongated nanostructures such as nanofibers. The nanofibers may be of an ionic solid, a hydrated salt, a molecular solid, or aggregated colloidal particles such as semiconductor partic...
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A composition comprises a semiconductor substrate having a crystallographic plane oriented parallel to a surface of the substrate and at least one planar semiconductor nanowire epitaxially disposed on the substrate, where the nanowire is aligned along a crystallographic direction of the substrate pa...
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The present invention provides device components geometries and fabrication strategies for enhancing the electronic performance of electronic devices based on thin films of randomly oriented or partially aligned semiconducting nanotubes. In certain aspects, devices and methods of the present inventi...
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Stabilized silver particles comprise particles comprising silver, a short-chain capping agent adsorbed on the particles, and a long-chain capping agent adsorbed on the particles. The short-chain capping agent is a first anionic polyelectrolyte having a molecular weight (Mw) of at most 10,000, and th...
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In one aspect, described herein are field effect chemical sensor devices useful for chemical and/or biochemical sensing. Also provided herein are methods for single molecule detection. In another aspect, described herein are methods useful for amplification of target molecules by PCR....
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Systems and methods for synthesizing silver nanoparticles (SNPs) using Trichoderma fungi have been developed. In an aspect, Trichoderma reesei was used for the extracellular synthesis of silver nanoparticles. In the biosynthesis of metal nanoparticle by a fungus, one or more enzymes or metabolites a...
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Highly sensitive Surface Enhanced Raman Spectroscopy (SERS) sensors are described in the form of a optical resonator and a metal nanostructure deposited on surface of the optical resonator. In one embodiment the optical resonator is in the form of a photonic crystal, but other optical resonators are...
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A method of forming a nanoscale three-dimensional pattern in a porous semiconductor includes providing a film comprising a semiconductor material and defining a nanoscale metal pattern on the film, where the metal pattern has at least one lateral dimension of about 100 nm or less in size. Semiconduc...
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A device including a micro component having an external surface and a nanofiber covering on at least a portion of the external surface of the micro component. A cooled micro component system further includes a droplet spray system for spraying liquid droplets onto the nanofiber covering to cool the ...
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A new method for forming an array of high aspect ratio semiconductor nanostructures entails positioning a surface of a stamp comprising a solid electrolyte in opposition to a conductive film disposed on a semiconductor substrate. The surface of the stamp includes a pattern of relief features in cont...
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In an embodiment, provided are nanoresonators, nanoresonator components and related methods using the nanoresonators to measure parameters of interest. In an aspect, provided is a nanoresonator component comprising an elongated nanostructure having a central portion, a first end, and a second end an...
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The present invention provides a microcantilever capable of independently measuring and/or controlling the electrical potential and/or temperature of a surface with nanometer scale position resolution. The present invention also provides methods of manipulating, imaging, and/or mapping a surface or ...
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A colorimetric array includes a substrate, a first spot on the substrate, and a second spot on the substrate. The first spot includes a first nanoporous pigment that includes a first nanoporous material and a first immobilized, chemoresponsive colorant. The second spot includes a second nanoporous p...
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The invention provides a drug-polymer nanoconjugate that includes a drug covalently bonded to a polymer. The nanoconjugate can include a block copolymer coating and/or an albumin coating. The drug of the drug-polymer nanoconjugate can be one or more of a variety of therapeutic agents linked to the p...
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Nanowire devices comprising core-shell or segmented nanowires are provided. In these nanowire devices, strain can be used as a tool to form metallic portions in nanowires made from compound semiconductor materials, and/or to create nanowires in which embedded quantum dots experience negative hydrost...
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Embodiments of the present invention relate to a method for synthesizing nanocrystalline zeolites, the method comprising contacting starting products that comprise a solvent, a silicon source, a cation base, an organic template, and an aluminum source, or any combination thereof sufficient to produc...
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Nanodispersions of inorganic clays in isocyanate may be created via pre-exfoliation, delamination, or both of the clay and subsequent mixing with isocyanate. In an embodiment, such an isocyanate nanodispersion is reacted with an isocyanate-reactive material or substrate to form a polyurethane nanoco...
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An optical element is provided with a fog reducing polymer layer. A reflection reducing nanostructure is formed on the surface of the fog reducing polymer layer....
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A monolithic pair of nanoscale probes, including: a substrate having a cavity that extends from a surface of the substrate into its body; a dielectric layer formed on the substrate; a pair of nanoscale probe precursors formed over the dielectric layer; a plurality of sub-monolayers of electrode mate...
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Methods and structural defect detectors for detecting a structural defect in composites are presented. An exemplary method includes forming a nanocomposite including a plurality of nanotubes mechanically aligned in a principal direction within a polymer matrix. A voltage is applied to the nanocompos...
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A supercapacitor comprising a cathode, an anode, a first single-walled carbon nanotube (SWNT) film electrode adjacent the cathode, a second SWNT film electrode adjacent the anode, and separator disposed between the first and second electrodes. The SWNT film electrodes may be manufactured by a non-fi...
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Nanoscale materials comprised of metal or metal oxide which are in the form of fibers or tubes or which have a porous structure can be prepared using composite fibers containing admixtures of polymers and metal precursors and/or metal oxide precursors....
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A process to coat a shear thickening fluid onto a material which comprises emulsifying dispersions of a shear thickening fluid (STF) dissolved in a miscible carrier fluid or a partially miscible carrier fluid to form an emulsion and applying said emulsion to the material. The invention also relates ...
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Isolated tellurite-resistant or selenite-resistant marine organisms capable of precipitating tellurium or selenium when grown aerobically are described. A method for using these isolated organisms to produce an aqueous suspension of purified nanoparticles comprising tellurium or selenium and the nan...
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Disclosed herein are compounds and compositions including a polyglycerol nanocarrier, a therapeutic agent or imaging agent, and optionally a targeting agent. In certain aspects the disclosed compounds include biocompatible hyperbranched polymer nanocarriers. Such compounds and compositions are usefu...
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Liposomes of a size of less than 200 nanometers target tumors and preferentially deliver imipramine blue to tumors, including brain tumors such as gliomas. The imipramine blue decreases the invasiveness of the tumors, and inhibits tumor metastasis. The liposomes include cholesterol and chemically pu...
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Synthesis of iron nanoparticles with a substantially unoxidized iron core and a biocompatible coating is described. The nanoparticles are formed by reacting an iron salt solution with a reducing agent in a substantially oxygen-free environment and exposing the formed iron particles to a biocompatibl...
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Briefly described, embodiments of this disclosure include multimodality nanostructures, methods of forming the multimodality nanostructures, and methods of using the multimodality nanostructures....
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The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close p...
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The present invention provides a ligand-nucleic acid nanostructure that promotes cell-cell interaction. Specially, the invention provides a ligand-nucleic acid nanostructure for treating tumor in a mammal. The methods of using and making the composition comprising a ligand-nucleic acid nanostructure...
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Fiber reinforced composites fabricated using a low-temperature, solution-based growth of nanowires such as ZnO nanowires on the surface of the reinforcing fibers such as carbon fibers and functionalized aramid fibers. The composites with nanowire interphase may have an enhanced fiber/matrix interfac...
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Methods, devices, and compositions of matter related to high efficiency InGaN-based photovoltaic devices. The disclosed synthesis of semiconductor heterostructures may be exploited to produce higher efficiency, longer lasting, photovoltaic cells....
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Substrates may be bonded according to a method comprising contacting a first bonding surface of a first substrate with a second bonding surface of a second substrate to form an assembly; and compressing the assembly in the presence of an oxidizing atmosphere under suitable conditions to form a bondi...
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The present invention is directed to systems, devices and methods for identifying biopolymers, such as strands of DNA, as they pass through a constriction such as a carbon nanotube nanopore. More particularly, the invention is directed to such systems, devices and methods in which a newly translocat...
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A method of producing carbon nanotubes includes directing a flow of a gas over a substrate to provide growth of at least one carbon nanotube in a carbon-nanotube-growth region of the substrate; applying an electric field to the carbon-nanotube-growth region of the substrate after the at least one ca...
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The disclosed subject matter is directed to a method for producing nanoparticles, as well as the nanoparticles produced by this method. In one embodiment, the nanoparticles produced by the disclosed method have a high defect density....
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A method of manufacture of a luminescent nanoparticle probe system includes forming a bismuth sulfide core; and coating the bismuth sulfide core with a shell....
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A miniature device for generating shock waves using the energy of combustion of a nanoenergetic material and directing the shock waves into biological tissues is described....
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A kit for providing a contrast enhancer in a mammal for contrasting during imaging of the mammal comprises functionalized gold nanoparticles configured to be directed to one or more of a target organ, tissue and lesion of the mammal....
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The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from soy or lentil plant material or a reactive extract thereof of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making bi...
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The invention relates to compositions and methods of using electrophoresis separation matrices. The invention provides nano-particle comprising separation matrices having increased conductivity at low voltage....
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Nanoparticles having a mean particle size of less than about 25 nanometers and a mean pore size of less than 10 nanometers, and a mean surface area of at least 500 m2/g; nanoporous films of such nanoparticles; and composites and devices containing such nanoparticles and nanoporous films....
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A sensor electrode for the detection of nucleotides in a biological sample is described. The sensitivity of the electrode is enhanced by the nanostructured sensor architecture that increases the available surface area of the electrode. The electrode detects nucleotides using standard electrochemical...
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The present invention describes processes for coating substrates with a nanocomposite SiCON material. In addition, the present invention describes the dielectric nanocomposite coatings....
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An apparatus or method can include forming a graphene layer including a working surface, forming a polyvinyl alcohol (PVA) layer upon the working surface of the graphene layer, and forming a dielectric layer upon the PVA layer. In an example, the PVA layer can be activated and the dielectric layer c...
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Systems and methods for hierarchical assembly of nanostructured organic heterojunctions for photovoltaic devices are described. Particularly, an apparatus for converting light energy to electrical energy is provided. An apparatus includes one or more organic photovoltaic devices. Photovoltaic device...
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The present invention relates to methods for fabricating nanoscale electrodes separated by a nanogap, wherein the gap size may be controlled with high precision using a self-aligning aluminum oxide mask, such that the gap width depends upon the thickness of the aluminum oxide mask. The invention als...
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A method for treating a surface of a medical implant to create nanostructures on the surface that results in increased in-vivo chondrocyte adhesion to the surface. Further, disclosed is a method to fabricate a drug delivery system. The drug delivery system includes a medical implant that has undergo...
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An antibody-conserving method for linking a therapeutic platinum compound to nanoparticles comprising Au Iike-Fe3O4, which is used for both drug delivery and tumor diagnosis....
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The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the following steps. First, the sorbent material is provided. The sorbent material, in one embodiment, is nano...
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Disclosed herein are magic size nanoclusters comprising lead and one or more chalcogens. The disclosed magic size nanoclusters have both spectrally narrow fluorescence and ultra-high quantum efficiencies. Further disclosed herein is a method for preparing PbS, PbSe, and PbTe magic size nanoclusters....
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A sensor chip and detection device are disclosed. The sensor chip includes a substrate, at least a portion of which is covered by a metal nanoparticle film; a first nucleic acid molecule that is characterized by being able to (i) self-anneal into a hairpin conformation and (ii) hybridize specificall...
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The self-assembly of polyhedral nanostructures having at least one dimension of about 100 nm to about 900 nm with electron-beam lithographically patterned surfaces is provided. The presently disclosed three-dimensional nanostructures spontaneous assemble from two-dimensional, tethered panels during ...
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Methods of forming a gated, self-aligned nano-structures for electron extraction are disclosed. One method of forming the nano-structure comprises irradiating a first surface of a thermally conductive laminate to melt an area across the first surface of the laminate. The laminate comprises a thermal...
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Compositions of nanoparticles and targeting moieties for imaging and treating Chlamydial infection are provided, including nanoparticles conjugated to folic acid and comprising at least one antibiotic effective against Chlamydia....
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A nanodevice composition including N-acetyl cysteine linked to a dendrimer, such as a PAMAM dendrimer, is provided. Also provided is a nanodevice for targeted delivery of a compound to a location in need of treatment. The nanodevice includes a PAMAM dendrimer linked to the compound via a disulfide b...
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A particle-rod nanostructure is disclosed. The nanostructure comprises an inorganic nanoparticle coated with a capping agent and an organic crystalline rod nucleated on the capped inorganic nanoparticle in a one-dimensional growth pattern....
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The present invention involves a method of delaminating aggregated particles of natural silicate, nanoplatelet, nanofiber, or nanotube structures. The method comprises diffusing a coating agent in a substantially supercritical fluid between the aggregated particles and catastrophically depressurizin...
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Nanostructure-beta-blocker conjugates are provided. Additionally, methods of synthesizing nanostructure beta-blocker conjugates and their use in the treatment and prevention of bone disease, such as osteoporosis, are also provided....
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A fabrication process for conformal coating of a thin polymer electrolyte layer on nanostructured electrode materials for three-dimensional micro/nanobattery applications, compositions thereof, and devices incorporating such compositions. In embodiments, conformal coatings (such as uniform thickness...
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Various embodiments of the present invention pertain to therapeutic compositions that comprise: (1) an active agent (e.g., paclitaxel); and (2) a nanoparticle (e.g., gold nanoparticle). In such embodiments, the active agent is covalently linked to the nanoparticle through a cleavable linker (e.g., a...
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Compositions comprising at least one type of carbon nanotube, at least one surfactant, and at least one polymer are disclosed. The compositions provide stable fluorescence over a wide range of pH in various embodiments. In some embodiments, the compositions are biocompatible. Methods for preparing t...
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We have discovered that size dependent solubility of large fullerenes in strong acids is dependent on acid strength. This provides a scalable method for separating large fullerenes by size. According to some embodiments, a method for processing a fullerene starting material comprises large fullerene...
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Methods of nanoencapsulation are described herein. Embodiments of the method utilize the coacervation of a cationic polyelectrolyte with an anionic polyelectrolyte to form a novel capsular matrix. In particular, the novel methods may be used to encapsulate a suspension of a hydrophobic material such...
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Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for mak...
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Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for mak...
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Articles comprising neat, aligned carbon nanotubes and methods for production thereof are disclosed. The articles and methods comprise extrusion of a super acid solution of carbon nanotubes followed by removal of the super acid solvent. The articles may be processed by wet- jet wet spinning, dry-jet...
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Carbon nanotubes grown on nanostructured flake substrates are disclosed. The nanostructured flake substrates include a catalyst support layer and at least one catalyst layer. Carbon nanotubes grown on the nanostructured flake substrates can have very high aspect ratios. Further, the carbon nanotubes...
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The present disclosure describes carbon nanotube materials and condensation polymers having at least one bridge between carbon nanotubes. Carbon nanotube materials comprise a plurality of functionalized single-wall carbon nanotubes linked to at least one other single-wall carbon nanotube by at least...
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A method of making a water soluble carbon nanostructure includes treating a fluorinated carbon nanostructure material with a polyol in the presence of a base. A water soluble carbon nanostructure comprises a fluorinated carbon nanostructure covalently bound to a polyol. Exemplary uses of water solub...
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Provided are polyamide nanocomposites incorporating carbon nanotubes and other filler species. Also provided are related methods....
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The present invention involves the interaction of radiation with functionalized carbon nanotubes that have been incorporated into various host materials, particularly polymeric ones. The present invention is directed to chemistries, methods, and apparatuses which exploit this type of radiation inter...
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Methods for synthesizing a semiconductor nanocrystal are provided comprising providing a semiconductive core; providing a metal precursor solution comprising a metal acetate, a non-polar solvent, trioctylphosphine, and trioctylphosphine oxide; providing a sulfur precursor solution; admixing the semi...
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Methods for dissolving carbon materials such as, for example, graphite, graphite oxide, oxidized graphene nanoribbons and reduced graphene nanoribbons in a solvent containing at least one superacid are described herein. Both isotropic and liquid crystalline solutions can be produced, depending on th...
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A nanoparticle coated with a semiconducting material and a method for making the same. In one embodiment, the method comprises making a semiconductor coated nanoparticle comprising a layer of at least one semiconducting material covering at least a portion of at least one surface of a nanoparticle, ...
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The present disclosure describes carbon nanotube arrays having carbon nanotubes grown directly on a substrate and methods for making such carbon nanotube arrays. In various embodiments, the carbon nanotubes may be covalently bonded to the substrate by nanotube carbon-substrate covalent bonds. The pr...
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The present disclosure describes micromechanical devices and methods for using such devices for characterizing a material's strength. The micromechanical devices include an anchor pad, a top shuttle platform, a nanoindenter in movable contact with the top shuttle platform and at least two sample sta...
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Metal/metal oxide nanoparticle-embedded polymer films were synthesized in situ wherein the polymerizing agent was utilized for both reduction and polymerization (such as curing). This in situ method avoids the use of any external reducing agent/stabilizing agent and leads to a uniform distribution o...
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In some embodiments, the present invention is directed to methods of fully integrating CNTs and the surrounding polymer matrix in CNT/polymer composites. In some such embodiments, such integration comprises interfacial covalent bonding between the CNTs and the polymer matrix. In some such embodiment...
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The present invention is directed toward methods of selectively functionalizing carbon nanotubes of a specific type or range of types, based on their electronic properties, using diazonium chemistry. The present invention is also directed toward methods of separating carbon nanotubes into population...
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Methods for separating magnetic nanoparticles are provided. In certain embodiments, a method is provided for separating magnetic nanoparticles comprising: providing a sample comprising a plurality of magnetic nanoparticles; passing the sample through a first magnetic field; at least partially isolat...
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Drilling fluids comprising graphenes and nanoplatelet additives and methods for production thereof are disclosed. Graphene includes graphite oxide, graphene oxide, chemically-converted graphene, and functionalized chemically-converted graphene. Derivatized graphenes and methods for production thereo...
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Methods for producing macroscopic quantities of oxidized graphene nanoribbons are disclosed herein. The methods include providing a plurality of carbon nanotubes and reacting the plurality of carbon nanotubes with at least one oxidant to form oxidized graphene nanoribbons. The at least one oxidant i...
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A contrast agent composition comprising at least one carbon nanotube and a metal catalyst. A method for obtaining a magnetic resonance image, the method comprising: administering to a subject a contrast agent composition, wherein a contrast agent composition comprises at least one carbon nanotube an...
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The formation of arrays of fullerene nanotubes is described. A microscopic molecular array of fullerene nanotubes is formed by assembling subarrays of up to 106 fullerene nanotubes into a composite array....
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The present invention is directed to nanodiamond (ND) surface coatings and methods of making same. Such coatings are formed by a covalent linkage of ND crystals to a particular surface via linker species. The methods described herein overcome many of the limitations of the prior art in that they can...
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The present invention includes single-walled carbon nanotube compositions for the delivery of siRNA and methods of making such single-walled carbon nanotube compositions. A single-walled carbon nanotube composition for delivery of siRNA includes a nonfunctionalized single-walled carbon nanotube; and...
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A system for measuring stress and strain in a sample is provided. The system includes a sample holder operable to support the sample; a stress inducing assembly operable to apply force to a selected location on the sample to deform the sample by a selected distance in a range from about 0.1 angstrom...
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Bilayer-nanoparticle compositions comprising a nanoparticle core and a lipid bilayer disposed around the exterior surface of the nanoparticle core are provided. In some embodiments, these bilayer-nanoparticle compositions may be dispersed in an aqueous solution. Associated methods are also provided....
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In various embodiments, the present disclosure describes processes for preparing functionalized graphene nanoribbons from carbon nanotubes. In general, the processes include exposing a plurality of carbon nanotubes to an alkali metal source in the absence of a solvent and thereafter adding an electr...
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A method for functionalizing the wall of single-wall or multi-wall carbon nanotubes involves the use of acyl peroxides to generate carbon-centered free radicals. The method allows for the chemical attachment of a variety of functional groups to the wall or end cap of carbon nanotubes through covalen...
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In various embodiments, methods for synthesizing single-crystalline zero-valent metal nanorings, such as single-crystalline copper nanorings, are described herein. The methods include providing a solution containing a metal cation, a complexing agent bound to the metal cation, thereby forming a meta...
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Compositions comprising nanoparticles (e.g., nanocrystals) of stishovite silica are described. Such nanoparticles may be made by (1) subjecting a mesoporous silica starting material (e.g., SBA-16 or KIT-6) to a pressure of less than about 20 GPa (e.g., about 12 GPa); (2) heating the mesoporous silic...
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Provided herein is a hydrothermal process for the rapid synthesis of inorganic nanomaterials (e.g., nanofibers) containing sodium, bismuth, titanium, and oxygen, as well as new compositions made thereby. The process involves heating an aqueous solution or suspension of suitable salts of aforemention...
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A light emitting device comprising a staggered composition quantum well....
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Preparation of dispersions of zero-valance nanoscale iron particles and one of soy protein, soy milk, or other soy derivative. The dispersions can be used to treat contaminated soil or water....
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Nano-size particles of calcium dioxide and magnesium dioxide for remediation of contaminated water or soil and processes for preparing and using nano-size particles of calcium dioxide and magnesium dioxide....
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Provided herein are new methods and apparatus for quantitative measurement and analysis of particles, including new apparatus systems to process and detect nanoparticles in suspension. By focusing a laser beam at the center of a reservoir, nanoparticles are concentrated by optical energy, and fluore...
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A new type of solid acid catalyst, which promises better catalytic performance than conventionally prepared supported metal oxides due to its precisely synthesized nanostructure has been described. The catalyst is nanoparticulate in form and is comprised of monolayers of tungstated zirconia of the f...
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This invention provides constructs comprising a targeting member immobilized on a detectable particulate, in which binding of the targeting member to a target structure on a surface of a cancer cell triggers internalization of the construct. Such constructs can be used to identify or monitor cancer ...
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A method for removing impurities from carbon nanotubes is described. Impurities may be removed from the carbon nanotubes by exposing the carbon nanotubes to a temperature, and controlling the temperature such that the temperature is constantly increasing to remove at least a portion of the impuritie...
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Functionalized bis-peptides as well as other amide-containing compounds are obtained by acylation of hindered amines. The functionalized bis-peptides are useful as shape-programmable nanostructures that are immune to denaturation and that contain arrays of functional groups having designed catalytic...
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The present invention is related to nano-particle compositions, methods of their preparation and applications thereof. The nano-particle compositions include silicon-containing nano-particles, a graphite matrix, carbon nanotubes and an amorphous carbon interface formed between the silicon-containing...
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The present invention is related to ternary metal transition metal non-oxide nano-particle compositions, methods for preparing the nano-particles, and applications relating in particular to the use of said nano-particles in dispersions, electrodes and capacitors. The nano-particle compositions of th...
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A new, non-wrapping approach to solubilize nanotubes, such as carbon nanotubes, in organic and inorganic solvents is provided. In accordance with certain embodiments, carbon nanotube surfaces are functionalized in a non-wrapping fashion by functional conjugated polymers that include functional group...
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A method for electrospraying nanosized metal or metal oxide particles onto a substrate. A metal oxide deposited fibrous material comprising a substrate, fibers and metal oxide particles may be made using the method. The material may be a flexible and porous fibrous matrix on which metal oxide partic...
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The present invention is direct to a nano-probe corona tool and uses thereof. A nano-probe corona tool is disclosed having a tip with a diameter in the nano-scale, typically around lOOnm. The nano-probe corona tool is constructed of electrically conductive material. On the other end of the tool, a p...
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Provided are functionalized nanodiamonds. Also provided are methods for fabricating such functionalized nanodiamonds. Also provided are composites including nanodiamonds and polymers. Also provided are methods for fabricating such composites including nanodiamonds and polymers. Also provided are ele...
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The invention relate to fibrous mats comprising chitosan nanofibers and, optionally, at least one filler material, at least one additive, or both. The invention also relates to methods of making same, and devices that include a fibrous mat comprising chitosan nanofibers....
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Provided are methods for dissolving polyamides under ambient conditions and for forming polyamide nanofibers by electrospinning. Also provided are methods for incorporating nanoparticles, including nanotubes, into such nanofibers....
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Disclosed are novel coatings and other components of articles of manufacture featuring the inclusion of nanodiamonds therein. Also disclosed are methods of achieving such inclusion and methods of utilizing the resultant, improved articles....
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A novel quantum dot capable of near infrared emissions at wavelengths of 750-1100 is made by forming solid solutions of metal sulfide, metal selenide or metal sulfide selenide by incorporating a suitable amount of an additional metallic element or elements to provide an emission wavelength in the ra...
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A method for the formation of surface enhanced Raman scattering substrates. The method produces thin substrates that have a nanoparticle ink deposited thereon. The nanoparticle ink may be any suitable nanoparticle ink such as silver, gold or copper nanoparticle ink which includes stabilized nanopart...
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The invention concerns methods for producing carbon nanotubes with embedded nanoparticles comprising providing a template comprising an anodized aluminum oxide membrane with a pore diameter of 20-200 nm; contacting the template with a solution containing nanoparticles; exposing the template and solu...
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Disclosed herein are nanoscale devices comprising one or more ferroelectric nanoshells characterized as having an extreme curvature in at least one spatial dimension. Also disclosed are ferroelectric field effect transistors and metal ferroelectric metal capacitors comprising one or more ferroelectr...
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An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm to 700 nm. Highly luminescent metal sulfide (MS) QDs are produced via an aqueous synthesis route. MS QD...
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Provided are surface-enhanced Raman spectroscopy (SERS) devices suitable for intra-subject (e.g., intracellular) observation, which devices may be of nanoscale size. Also provided are related SERS analysis methods....
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The present invention includes a composition for implantation in a patient, comprising surface-functionalized nanodiamonds and at least one biodegradable biocompatible polymer. The present invention also includes a surgical fixation device for use in a patient....
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The method involves adding drops of solution for nanostructure formation in water at a temperature above a predetermined temperature, in which the drops of solution floats to a substrate on a steam pad. The steam pad heats the substrate to evaporate the added drops, leaving and forming nanostructure...
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Disclosed is a method for producing regularly arranged nanowires from a nanowire-forming material on a substrate. Said method is characterized by the following steps: a) the material is introduced into a carrier liquid at a load remaining at least three orders of magnitude below the loading capacity...
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The invention relates to electrodes for lithium-ion accumulators comprising a metal film that is inert in relation to lithium ions and a plurality of silicon nanowires projecting from the film at least on a flat side of the film. Parts of the nanowires are surrounded by the metal film....
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This invention provides multimeric nanocarrier for in vivo delivery of a bioactive agent, comprising at least two peptide monomers reversibly or irreversibly linked with one or more of said bioactive agents, wherein said two or more of said peptide monomers are covalently linked by a biodegradable d...
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A method for preparing gallium nitride nanoparticles includes providing a pair of electrodes; the pair of electrodes being opposedly disposed to one another. One electrode of the pair of electrodes is filled with gallium nitride powder. The pair of electrodes is dipped in a liquid. An arc discharge ...
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Novel classes of multi-arm polyalkylene oxide-based materials including PEG nanocarriers, nanogel particles, and aggregated nanogel particles are disclosed. These classes of compositions may be associated with therapeutic agents and targeting moieties, or visibility enhancing agents, and may have a ...
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Nanoparticles are functionalized for use as bio-imaging probes using a novel, modular approach. Particle surface modification is based on a phosphonate monolayer platform on which was built a multi-segmented, multi-functional film: the first segment provided hydrolytic stability, the second aqueous ...
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Embodiments of the invention include nanoparticulate products of a flash nanoprecipitation process, the products comprising, in combination, pre-formed nanoparticles having properties of an upconversion phosphor and a hydrophobic organic compound having the properties of a photosensitizer, and a met...
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Oxide, oxysulfide, halide or phosphate host particles with a self-assembled organo- phosphonate monolayer covalently bonded thereto. Methods for coating the host particles and use of rare earth ion-doped particles in imaging methods and photodynamic therapy methods are also disclosed....
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Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out ...
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Methods for preparing rare earth doped monodisperse, hexagonal phase upconverting nanophosphors, the steps of which include: dissolving one or more rare earth precursor compounds and one or more host metal fluoride compounds in a solvent containing a tri-substituted phosphine or a tri-substituted ph...
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An optoelectronic device and a method of fabricating a photosensitive optoelectronic device includes depositing a first organic semiconductor material on a first electrode to form a continuous first layer; depositing a layer of a second organic semiconductor material on the first layer to form a dis...
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Nanocomposite materials comprising a metal oxide bonded to at least one graphene material. The nanocomposite materials exhibit a specific capacity of at least twice that of the metal oxide material without the graphene at a charge/discharge rate greater than about 10C....
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A nanocomposite material formed of graphene and a mesoporous metal oxide having a demonstrated specific capacity of more than 200 F/g with particular utility when employed in supercapacitor applications. A method for making these nanocomposite materials by first forming a mixture of graphene, a surf...
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An optoelectronic device and a method for fabricating the optoelectronic device includes a first electrode disposed on a substrate, an exposed surface of the first electrode having a root mean square roughness of at least 30 nm and a height variation of at least 200 nm, the first electrode being tra...
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Low-aspect ratio nanostructures, such as nanocups, nanorings, and arrays of nanocups and nanorings, methods of fabrication of nanostructures, and methods of using nanostructures are disclosed....
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A composition of a crystalline ferromagnetic material based upon nanoscale cobalt carbide particles and to a method of manufacturing the ferromagnetic material of the invention via a polyol reaction are disclosed. The crystalline ferromagnetic cobalt carbide nanoparticles of the invention are useful...
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A non-volatile bistable nano-electromechanical switch is provided for use in memory devices and microprocessors. The switch employs carbon nanotubes as the actuation element. A method has been developed for fabricating nanoswitches having one single-walled carbon nanotube as the actuator. The actuat...
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Nanoelements such as single walled carbon nanotubes are assembled in three dimensions into a nanoscale template on a substrate by means of electrophoresis and dielectrophoresis at ambient temperature. The current-voltage relation indicates that strong substrate-nanotube interconnects carrying mA cur...
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Nanoscale patterns prepared by lithography are used to direct the self-assembly of amphiphilic molecules to form patterned nanosubstrates having a desired distribution of chemical functional moieties. These patterns can be fabricated over a large area and require no special limitations on the chemis...
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Methods and compositions are described for organizing nanoparticles or microparticles into nanostructures or microstructures using collagen as a template....
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Methods and apparatus to generate carbon nanostructures from organic materials are described. Certain embodiments provide solid waste materials into a furnace, that pyrolyzes the solid waste materials into gaseous decomposition products, which are then converted to carbon nanostructures. Methods and...
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Ascorbate-conjugated liposomes and micelles, methods of making such liposomes and micelles, and methods of using such liposomes and micelles, such as for delivery of therapeutic and detection agents to the brain, are described....
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Stable nanoparticles comprising poorly soluble drugs are disclosed, as well as methods of making and methods of using such nanoparticles, e.g., as therapeutics and diagnostics....
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Nanoparticles containing nucleic acid and suitable for use as in vivo delivery agents for nucleic acids are provided. The nanoparticles use a covalent conjugate of a polycation such as polyethylenimine and phospholipids. The final DNA- containing nanoparticle has a vesicular structure with a polyple...
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Anti-angiogenesis agent-linked liposomes and micelles, methods of making such liposomes and micelles, and methods of using such liposomes and micelles, such as for delivery of therapeutic and detection agents to tumor cells, are described....
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Nanosubstrates as biosensors, methods of making such nanosubstrates, and methods of using such nanosubstrates to detect biomarkers are described....
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Libraries of nanoparticles comprising therapeutic agents and/or imaging agents are disclosed, as well as methods of making, customizing, and using such libraries of nanoparticles....
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Stable colloid nanoparticles comprising poorly soluble drugs are disclosed, as well as methods of making and methods of using such nanoparticles, e.g., as therapeutics and diagnostics....
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The invention provides a fast, scalable, room temperature process for fabricating metallic nanorods from nanoparticles or fabricating metallic or semiconducting nanorods from carbon nanotubes suspended in an aqueous solution. The assembled nanorods are suitable for use as nanoscale interconnects in ...
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Provided herein are peptides and nanoparticles conjugates thereof useful for the treatment of diseases and disorders mediated by GIPC/synectin, such as cancer....
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A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracel...
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The embodiments disclosed herein relate to hetero-nanostructure materials for use in energy-storage devices, and more particularly to the fabrication of hetero-nanostructure materials and the use of the hetero-nanostructure materials as battery electrodes. In an embodiment, a Si/TiSi2 electrode 1000...
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An apparatus for detecting the presence of a target molecule is disclosed which includes a conductive nanostructure, a non-conductive polymer coating on at least a portion of the nanostructure, and a cavity formed in the polymer coating having a shape corresponding to the shape of the target molecul...
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The present invention generally relates to nanostructure compositions, as well as methods for the controlled synthesis of nanostructures, such as carbon nanotubes. In some embodiments, methods involving iterative growth of a nanostructure template to homogeneously produce nanostructure compositions ...
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Nanoscopically thin photovoltaic junction solar cells are disclosed herein. In an embodiment, there is provided a photovoltaic film 100 that includes a p-doped region 102, an n-doped region 106, and an intrinsic region 104 positioned between the p-doped region 102 and the n-doped region 106, wherein...
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Nanoscale photovoltaic devices fabricated from nanoscale waveguides that receive, propagate, and convert incident light into electrical neural signals, and methods of using these photovoltaic devices for visual perception are disclosed herein. A visual neuroprosthetic device includes an array of nan...
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The embodiments disclosed herein relate to the fabrication of complex two-dimensional conductive silicide nanostructures, and methods of fabricating the nanostructures. In an embodiment, a conductive silicide includes a plurality of connected and spaced-apart nanobeams linked together at an about 90...
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A device and method is presented for achieving a high field emission from the application of a low electric field. More specifically, the device includes a substrate wherein a plurality of nanostructures are grown on the substrate. The relationship of the nanostructures and the substrate (the relati...
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An apparatus and methods for optical switching using nanoscale optics are disclosed herein. A nano-optics apparatus for use as an optical switch includes a metallic film having a top surface, a bottom surface and a plurality of cylindrical channels containing a dielectric material, the metallic film...
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An apparatus and methods for nanolithography using nanoscale optics are disclosed herein. Submicron-scale structures may be obtained using standard photolithography systems with a de-magnifying lens. A de-magnifying lens for use in a standard photolithography system includes a film having a top surf...
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Nanoscale optical probes for use with nanoscale optical microscopy are disclosed herein. A nanoscale optical probe for use with a near-field scanning optical microscope includes an inner conductor having a top end, a bottom end, and a body; a dielectric material engaging the inner conductor; and an ...
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An apparatus and methods for manipulating light using nanoscale cometal structures are disclosed. A nanoscale optics apparatus for manipulating light includes a plurality of nanoscale cometal structures each comprising a dielectric material located between a first electrical conductor and a second e...
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An apparatus and methods for solar conversion using nanoscale cometal structures are disclosed herein. The cometal structures may be coaxial and coplanar. A nanoscale optics apparatus (100) for use as a solar cell comprises a plurality of nanoscale cometal structures each including a photovoltaic ma...
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An apparatus and method for solar conversion using nanocoax structures are disclosed herein. A nano-optics apparatus for use as a solar cell comprising a plurality of nano-coaxial structures comprising an internal conductor surrounded by a semiconducting material coated with an outer conductor; a fi...
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Disclosed herein too is a method that includes dispersing nanotubes in media that comprises flavin moieties substituted with solubilizing side chains, and/or non-flavin containing molecular species; self-assembling the flavin moieties and other non-flavin containing molecular species in a pattern th...
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Nanowires, films, and membranes comprising ordered porous manganese oxide-based octahedral molecular sieves and methods of making the same are disclosed. A method for forming nanowires includes hydrothermally treating a chemical precursor composition in a hydrothermal treating solvent to form the na...
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The present invention provides biocompatible composite materials that can be fabricated into a scaffold having properties suitable for bone repair and regeneration. These scaffolds have sufficient mechanical strength to be useful for the repair and regeneration of cortical bone....
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A method and corresponding system for providing a uniform nanowire array including uniform nanowires composed of at least three elements is presented. An embodiment of the method includes growing an array of two-element nanowires, and thereafter uniformly doping or alloying each two-element nanowire...
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A method of manufacturing a nanopatterned biophotonic structure includes forming a customized nanopattern mask on a substrate using E-beam lithography, providing a biopolymer matrix solution, depositing the biopolymer matrix solution on the substrate, and drying the biopolymer matrix solution to for...
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A sensor system for detecting a chemical or biological species includes a sensing element and a bias and measurement circuit. The sensing element includes nanochannels, each having an outer surface functionalized to chemically interact with the species to create a corresponding surface potential, an...
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A bundle of drawn fibers that have X-ray scintillating unagglommerated nanocrystallite particles in plastic or glass cores of down to 0.1 micron spacing and claddings of X-ray absorbing compounds in the cladding composition. Optional is a cover to the bundle that blocks light from leaving the bundle...
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Disclosed are methods of manufacturing nanoparticles such as quantum dots at desired nanopore locations in a membrane. The methods disclosed use voltage-driven electrolyte flow to drive the nanoparticle formation....
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Defined nanoparticle cluster arrays (NCAs) with total lateral dimensions of up to 25.4 [mu]m by 25.4 [mu]m have been fabricated on top of a 10 nm thin gold film using template guided self-assembly. This approach provides precise control of the structural parameters in the arrays allowing a systemati...
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A glucose sensor employs a programmable glucose sensor array of a relatively large number of nanoelectronic devices (e.g. semiconductor field-effect devices) having control surfaces functionalized with a glucose-reactive substance and generating sensing signals indicative of sensed glucose level of ...
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The present invention generally relates to nanoantenna arrays and methods of their fabrication. In particular, one aspect relates to nanoantenna arrays comprising nanostructures of predefined shapes in predefined patterns, which results in collective excitement of surface plasmons. In some embodimen...
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Embodiments disclosed herein relate to a method of detecting specific DNA sequences and the application of this method in the detection of pathogens, viruses, drug-resistant pathogens, genomic variations associated with disease/disorder susceptibility etc. based on specific signature sequences uniqu...
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Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof. Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have been used to fabricate synthetic nanopores in thin solid-state membranes with sub-nanometer resolution. A new cla...
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Disclosed are sensors, devices, systems, arrays of sensors and methods, including a sensing device that includes a sensor including one or more nanochannels constructed from semiconductor material and connected at their opposite ends to electrodes, the one or more nanochannels having at least one el...
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Polymer-based nanocomposites and a method for forming polymer-based nanocomposites for EMI shielding includes three nanofillers used in a formation of a hierarchy in structure, length, size, and dimension. The nanofillers formulation comprises 18 wt % of nickel-coated carbon fibers (NCCB), 7 wt % of...
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The disclosure relates to compositions and methods of forming nanoemulsions, e.g., containing an active component, in combination with lipophilic components such as oils, hydrophilic components such as water, and one or more surfactants capable of causing a temperature-dependent phase inversion, suc...
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The present invention relates to methods of fabricating nanostructures using a replacement reaction. In a preferred embodiment, metal particles in an inert atmosphere undergo a replacement reaction to form a layer on the metal particle which is removed to form a high surface area nanostructure. A pr...
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Methods of the invention allow rapid production of high-porous, large-surface-area nanostruetured metal and/or metal oxide at attractive low cost applicable to a wide variety of commercial applications such as sensors, catalysts and photovoltaics....
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Disclosed is a general methodology to create nano fibers of therapeutic molecules that have a dual role, as both the delivery vehicle and the drug itself. It is shown that with proper molecular design, the integration of enzymatic reaction and self-assembly provides a powerful method to create molec...
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The invention relates to synthetic platelet compositions and methods useful in diminishing bleeding and blood loss. The synthetic platelets of the invention can comprise a biocompatible, biodegradable polymer, including, for example, a poly(lactic-co-glycolic acid)-poly-L-lysine (PLGA-PLL) block cop...
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The present invention relates to devices which operate on gradient optical forces, in particular, nanoscale mechanical devices which are actuable by gradient optical forces. Such a device comprises a waveguide and a dielectric body, with at least a portion of the waveguide separated from the dielect...
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Carbon nanotube (CNT)-based compositions for activating cellular immune responses are provided. The CNTs function as high surface area scaffolds for the attachment of T cell ligands and/or antigens. The CNT compositions function as artificial antigen-presenting cells (aAPCs) or as modular vaccines. ...
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The present invention relates to a device and method for determining the presence of a specific compound in solution. The device includes a nanosensor having an electrically conducting pathway between at least a first and second contact. The device also includes a first receptor, suitable for bindin...
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A process for growth of boron-based nanostructures, such as nanotubes and nanowires, with a controlled diameter and with controlled chemical (such as composition, doping) as well as physical (such as electrical and superconducting) properties is described. The boron nanostructures are grown on a met...
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The present invention provides a microfluidic purification chip for capturing a biomarker from a physiological solution. The present invention also provides a method of capturing and releasing a biomarker, wherein the biomarker is originally in a physiological solution. The present invention further...
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Filters comprising a layer of multiwall carbon nanotubes dispersed on a porous substrate, with or without a layer of single wall carbon nanotubes dispersed on top of the layer of multiwall carbon nanotubes, have been fabricated and shown to be useful for removing constituents from fluids....
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The method for cell identification and quantification comprises bonding specific surface proteins of cells immobilised on the surface of the electrochemical transducer with specific antibodies conjugated with gold nanoparticles, and subsequent nanoparticle detection and quantification through hydrog...
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The invention relates to an identification and verification system and to an associated method for the identification and verification of documents, based on the use of nanoparticles embedded or absorbed in the medium forming the document, whereby the different optical reflectance characteristics of...
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The invention relates to multifunctional nanostructures consisting of superparamagnetic magnetoferritin which can also comprise chains of a biocompatible polymer covalently bound to the surface thereof. The invention also relates to a method for obtaining said nanostructures, as well as to the use t...
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The present invention relates to a method for obtaining nanoparticles of a metal selected from the group consisting of Ag, Pt, Pd and Au, which comprises the steps of: a) preparing an aqueous solution of a metallic salt and an aqueous citrate-salt mother solution, respectively; b) preparing an aqueo...
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It comprises the following steps: (i) Depositing on glass a nickel electrode layer; (ii) depositing a layer of photosensitive material (photoresist) on the electrode layer; (iii) conferring a pattern on the photoresist having photolithographic form, covering it with a pattern mask and exposing it to...
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Substrate the melting point whereof is between 1300 DEG C and 1600 DEG C having a layer of micromonocrystals of gold (III), said micromonocrystals having terraces of an area between 1.5 and 10.0 [mu]m2 and a roughness of less than 1 AA. This substrate is manufactured by a preparation procedure compr...
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The invention relates to a method and a device which can be used to modulate an electrically excited light source according to an electric signal and which can be used for silicon photonics. The device includes a field-effect transistor having a dielectric gate means with embedded dopants and nanocr...
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A nano-scale manipulator (10) comprises a mounting deck (11) and a frame (12), the deck (11) being moveably secured to the frame (12) by two flexural joints permitting movement of the deck relative to the frame in first and second respective, mutually orthogonal directions of movement. Manipulator (...
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The present invention relates to the use of atomic layer deposition (ALD) techniques to enhance the acid catalytic activity of nanoporous materials....
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The device comprises a substrate, a layer present thereon and a nanostructure penetrating said layer, which nanostructure defines a nanoscale passageway through which a molecule to be analyzed can pass through the passageway, wherein the nanostructure has, in cross-sectional view, a substantially tr...
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A method involving ion milling is demonstrated to fabricate open-nanoshellsuspensions and open-nanoshell monolayer structures. Ion milling technology allows theopen-nanoshell geometry and upward orientation on substrates to be controlled.Substrates can be fabricated covered with stable and dense ope...
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The present invention refers to a method for the preparation of a reinforced thermoset polymer composite, said thermoset polymer composite comprising coated fibres, the coating being used as a vehicle for the introduction of carbon nanotubes into the thermoset polymer, the preparation of said reinfo...
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The present invention relates to the field of drug delivery nanosystems. More precisely, the present invention concerns a copolymer with advantageous properties for the outer coating of various nanoparticles. Said copolymer comprises at least three types of monomers with stealthy, coupling and thera...
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The invention relates to a chemical reactor having a nanometric structure and including at least one member in which is formed at least one reaction chamber, said chamber being at least partially filled with a high specific-surface material having a specific surface higher than 5 m2/g, characterised...
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The present invention relates to labelled silica-based nanoparticles with enhanced properties, to process for preparing them and to uses thereof....
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The invention relates to a nanoprobe comprising a silica fiber (2) with an end opening having a diameter of less than 100 nm, and a metallic sheath (11). The total diameter of the silica part and the metallic sheath (11) is less than 300 nm. The invention also relates to a method for producing one s...
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The invention relates to a method of manufacturing nanoscale cubic boron nitride and to the nanoscale cubic boron nitride thus obtained. The method according to the invention of manufacturing nanoscale boron nitride of cubic structure is characterized in that it comprises the following steps: a) com...
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The invention provides a new type of transistor comprising a nanowire structure adapted to provide a tunnel barrier such that an applied gate voltage causes a current to oscillate, as the gate voltage is increased, to provide a region of negative transconductance. The device presents oscillations of...
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A process for producing nanoparticles comprises the steps of preparing silver seeds in the presence of a water soluble polyanionic polymer and growing the silver seeds to form nanoparticles. The polyanionic polymer may be poly (sodium styrenesulphonate)....
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A sensor for detecting of an analyte in a solution phase comprises a plurality of functionalised silver nanoplates wherein a functionalising agent is directly bonded to the surfaces of the nanoplates. The nanoplates provide a detectable wavelength shift change in their local surface plasmon resonanc...
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The invention provides a method of making a nano-carbon structure comprising providing a first layer of nano-carbon particles; depositing a second layer of resin on said layer of nano-carbon particles; and annealing said first and second layers to provide a carbon composite nanostructure. The nano-c...
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The invention provides a system and process of patterning structures on a carbon based surface comprising exposing part of the surface to an ion flux, such that material properties of the exposed surface are modified to provide a hard mask effect on the surface. A further step of etching unexposed p...
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The invention provides the use of a membrane comprising a support layer and an electrically conductive porous nanotube layer for generating power from water by pressure retarded osmosis. The electrically conductive nanotubes may be arranged in a mat, alternatively the electrically conductive nanotub...
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Provided herein is a method for the isolation or removal of a cellular component from a cell that comprises the steps of applying a pulse of nanoparticles to the cell, allowing the nanoparticles to traffic through the cell for a period of time sufficient to allow the nanoparticles locate to and inte...
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A light emitting or detecting device (41) with a substrate (44) with a surface, an array of elongate nanostructures (42) having a first end supported by the substrate (44), and a second free end projecting away from the surface; a thin insulating layer (45) formed on the surface and about the nanost...
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A label is disclosed comprising a nanoparticle wherein the nanoparticle surface is functionalised to comprise at least one dendrimer having at least one activatable functional group for conjugating a target analyte to the functionalised nanoparticle, wherein the dendrimer has a stabilising effect on...
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The present invention provides nanoparticles for treatment of inflammatory diseases. The nanoparticles preferably comprise chitosan and a siRNA targeting a mRNA encoding a pro-inflammatory cytokine, such as e.g. tnf-alfa. A preferred route of administration of the nanoparticles is by injection intra...
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The present invention relates to nanoparticles comprising osteopontin and a polymer carrier, preferably a cationic carrier. Preferably, the cationic carrier is chitosan. Osteopontin and/or the cationic carrier may have bioactivity and/or the nanopar-ticle may comprise an additional component with bi...
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The present invention relates to dehydrated nanoparticles comprising chitosan and a nucleic acid. Preferably, the nucleic acid is a siRNA. Dehydrated nanoparticles of the invention have improved storage characteristics. The particles may be used in screening methods, e.g. where they have been dried ...
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The present invention relates to nanostructured composites comprising a nanotube network which is at least partially embedded within a carbon layer. The present invention particularly relates to conducting nanostructured composites for use in the fields of energy conversion, energy storage and also ...
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The present invention relates to a process for the preparation of graphene which can be used in the development of graphene paper or films, graphene-based composites and articles for nanoelectronics, nanocomposites, batteries, supercapacitors, hydrogen storage and bioapplications. This process compr...
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The present invention relates to an electrode useful in electrochemical nanobiosensors for determining the presence or concentration of analytes in aqueous samples. In particular, the electrode comprises a biocatalyst or other bioreceptor entrapped in a conducting polymeric film deposited on a condu...
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A method of coating nanoparticles comprising subjecting nanoparticles, a coating precursor and one or more reagents to shear, wherein the coating precursor and the one or more reagents react to provide a coating on the nanoparticles....
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The present invention relates to a process for the preparation of calix[n]arene derivatives, in particular phosphonated calix[n]arenes. The present invention also relates to nano-structures of phosphonated calix[n]arenes....
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A method of separating at least one carbon nanotube having a desired diameter and/or chirality from a mixture of carbon nanotubes having different diameters and/or chiralities is provided. A calixarene of formula (I): wherein n>=4; X is PO3H2, Ra-PO3H, SO3H, or Ra-SO3H; Y is Rb, OH, or ORb; and Ra a...
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The present invention provides a method of fabricating a device for detecting an analyte, the method comprising depositing a solution or suspension of two or more components of a material responsive to an analyte on a response platform to form said material on the response platform, wherein said mat...
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The present invention relates to polymer microgel beads having a polymeric matrix with nanomagnetic particles dispersed substantially uniformly therethrough, wherein a steric stabiliser is associated with the particles, the steric stabiliser being a polymeric material that (i) does not form part of ...
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The present invention relates to polymer microgel beads having a polymeric matrix with nanomagnetic particles dispersed substantially uniformly therethrough, wherein a steric stabiliser is associated with the particles, the steric stabiliser being a polymeric material that (i) forms at least part of...
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A method of manufacturing a bulk heterojunction device having a first charge transport material (250) and a second charge transport material (252). The method includes the step of forming a nanoscale relief structure (256) in the device by an embossing process. At least one of the charge transport m...
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The present invention relates to a method for preparing a radiolabeled macromolecule, the method comprising contacting a macromolecule with a carbon encapsulated nanoparticle composite having a radioactive particulate core in an aqueous medium comprising a pH selected to promote short-range attracti...
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The present invention relates to a method for preparing a radiolabeled synthetic polymer, the method comprising contacting a synthetic polymer with a carbon encapsulated nanoparticle composite having a radioactive particulate core in an aqueous medium comprising an electrolyte concentration or pH se...
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The invention relates to an imprinting device for imprinting nano/micro structures. The imprinting device comprises a second expandable cavity constituted in part by a membrane of the stamp. The membrane is flexible and formed in such a way so that when fluid is pumped into the expandable cavity the...
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A system is provided for forming carbon nanotubes comprising growing carbon nanotubes using a hot filament CVD system....
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A photovoltaic device includes a built-in electric field generated by electric dipoles of nanoparticles embedded in a photoconducting host....
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Anti-biofouling nanocomposite material at least partially loaded with copper or silver ions and methods for making same are disclosed. Metal affinity ligands are covalently bound to the polymers that are charged with the metal ions to allow for slow release of metals.
The present invention relate...
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A three-dimensional milling method and apparatus is disclosed for milling micrometre and a nanometre scale three-dimensional structures. The apparatus includes an ion column (12) operable to generate a milling beam onto a substrate (20) held on an instrument stage (18). A patterning computer (22) is...
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The invention concerns a process for the continuous treatment of an emulsion and/or a micro-emulsion assisted by an "expanded liquid' for the production of micro- and/or nano-particles or micro- and/or nano- spheres containing one or more active ingredients. In particular, a liquid solvent expanded ...
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The present invention relates to a process for preparing a new nanoporous crystalline form of syndiotactic polystyrene, to the thus obtained crystalline form, to molecular-complex crystalline phases obtained by exposition of such crystalline form to low- molecular-mass molecules, and to the related ...
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The invention concerns a system based on polymeric composites with carbon nanotubes to obtain low-cost and high accuracy temperature sensors. The composite material is obtained by homogeneously dispersing a suitable amount of carbon nanotubes having conductive characteristics within a polymer matrix...
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The present invention introduces a small-size temperature sensor, which exploits a random or oriented network of un-functionalized, single or multi-walled, carbon nanotubes to monitor a wide range of temperatures. Such network is manufactured in the form of freestanding thin film with an electric co...
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The invention relates to a system for delivering biologically active molecules to the cytosol of cells. In particular, the invention relates to substantially spherical nanoparticles comprising two polyvalent components of opposite charge....
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Methods, compositions and kits for analyzing a chemical analyte using an electrochemical cell connected to a measuring apparatus are provided. The electrochemical cell contains a solution having one or more conductive or redox active NPs (nanoparticles), one or more chemical analytes, and an indicat...
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A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communica...
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Solar cells having at least one N-type material layer and at least one P-type material layer forming a patterned p-n junction are described. A conducting layer may provide electrical communication between the p-n junction and an electrode layer....
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The present invention provides a composition and method of forming an amorphous drug-loaded particle by forming one or more amorphous drug-loaded nanoparticles comprising one or more active agents stabilized by one or more polymers, desolvating the one or more amorphous drug-loaded nanoparticles to ...
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Disclosed are nanoparticles for delivery of drugs and/or nutraceuticals that include a fibroin polypeptide and a drug or nutraceutical, wherein the nanoparticle has a diameter of about 1 nm to about 500 nm, and compositions of the nanoparticles. The nanoparticles may further include a chitosan, or a...
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A near-infrared mediated drug delivery system comprising a plurality of microspheres made of polymeric material, each sphere containing a plurality of hollow gold nanospheres together with drug product, wherein upon NIR irradiation, the drug product is released from the microsphere....
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A method of producing a monolithic metal or metal composite having a hierarchic pore structure, the method comprising the steps of: selecting a template material, said template material having a porous structure; contacting the template material with a solution of the or each metal to be structurali...
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A method of forming a stable nanodispersion comprising the steps of: (a) providing a host fluid, a particle fluid to be dispersed in the host fluid and a stabiliser; and (b) subjecting the host fluid, the particle fluid and the stabiliser to a high shear comminution process whereby a dispersion of p...
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A method of forming granules, the method comprising forming a suspension of a nanopowder such as a nano zirconia powder containing yttria. The powder is formed from a suspension, and freon is added directly to the suspension as an additive. The suspension is then granulated by spray freeze drying, a...
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Quantum cascade lasers (QCLs), and methods of manufacture of QCLs, comprising an active portion. In some embodiments, the active portion can comprise: a plurality of tensiley strained quantum barrier layers, each comprising Ga y In1- y As; and a plurality of compressively strained quantum well layer...
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A material comprising elongate filamentous peptide- or protein-based nanostructures. The nanostructures are assembled to be connected together and aligned substantially parallel with respect to each other. The alignment of the nanostructures (at least within one domain) is nematic alignment. The ind...
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A semiconductor device which comprises a channel layer formed from a semiconductor channel component material in the form of crystalline micro particles, micro rods, crystalline nano particles, or nano rods, and doped with a semiconductor dopant....
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A method for forming an organic or partly organic switching device, comprising: depositing layers of conducting, semiconducting and/or insulating layers by solution processing and direct printing; defining microgrooves in the multilayer structure by solid state embossing; and forming a switching dev...
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An inventive quantum cascade laser structure comprises a number cascades (100), each comprising a number of alternately arranged quantum well layers (110a-110j) and barrier layers (105-105J). Both the material at least one quantum well layer (110a-110j) and the material at least one barrier layer (1...
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A quantum well structure according to the invention includes a quantum well layer ( 107 ) arranged between two barrier layers ( 109, 112 ). It is distinguished in that at least one of the barrier layers ( 109 ) includes nanostructures ( 110 ) which compensate or modulate a lateral homogeneity of the...
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Disclosed is an organic-inorganic hybrid nano particle comprising a conjugate of a nucleic acid and a polyethylene glycol chain bound covalently to the nucleic acid and a calcium ion (Ca2+) and a phosphate ion (PO4 3-). The particle can be used as an effective delivery system for delivering a nuclei...
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Tech ID: 21232
Brief Description
Researchers have developed a Laplace pressure trap that can fuse droplets from different inlets and fuse droplets generated at different frequencies. The device traps and fuses droplets passively by balancing the driving hydrostatic pressure with increasing Lapla...
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Background
Bioresponsive materials offer a promising commercial opportunity and demonstrate great potential in the medical diagnostics and drug delivery sector. Compared with conventional chemistry, they are more sensitive, simple to use and more compatible with biological samples. Enzymes in pati...
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Electrochemical biosensors based on nanotubes or nanowires could be widely used in diagnostic, research, and security applications. However, the problems associated with functionalizing and placing these nano-elements on a device have prevented the practical application of this technology.
Univer...
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BACKGROUND: A light-emitting diode (LED) is a semiconductor device that emits visible light when an electric current passes through it. Traditionally, LEDs were made with inorganic materials. However, inorganic semiconductor LEDs lack ease of processibility on large and flexible substrates. In the ...
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BACKGROUND: Gold nanoparticles, particularly with dimensions less than 10 nm, exhibit unexpectedly high catalytic activities toward different types of reactions, a property not revealed in bulk gold. In order to obtain high catalytic activity, gold nanoparticles are generally dispersed on support m...
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Objective/function
The laboratory is active in the field of investigation of colloidal systems and applications of new colloids, with a focus on formation and characterization of dispersed systems, ranging in size from nanoparticles and nanocapsules through microparticles and microcapsules, up to...
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Highlights
This unique film process is a breakthrough technology, enabling organic layers of molecular thickness to be laid directly on a silicon die without loss of performance and with stable electronic properties for the mass production of inexpensive, advanced semiconductors Provides a soluti...
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ighlight
Electroplating method for preparing sol-gel thin films Allows coating of complex shaped objects Successfully demonstrated ability to include metals and nano-particles in sol-gel Platform technology for thin film deposition Our Innovation
An improved method for forming sol-gel films by...
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Highlights
Optical fibers that carry information for telecommunications and military applications are most transparent in near infra red wavelengths Polymer-based electronic components that emit visible light are lower cost and provide greater adaptability, but until now their development has bee...
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Highlights
Semiconductor nanocrystals replace conventional dye molecules as FRET (fluorescence resonance energy transfer) donors for enhanced optical resolution in near field scanning optical microscopy (NSOM)
Applications in high resolution microscopy for biology and materials science FRET is w...
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Highlights Gold-tipped nanocrystals – nanodumbells – for nano sized transistors Building blocks for miniature computers, nanosensors for chemical and biological molecules, and for biomedical applications Prototypes of gold-tipped rods and tetrapods demonstrated in the lab. Our Innovation
A simpl...
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Highlights
Nanoparticles of metals, semiconductor material, magnetic materials such as Fe2O3, Co, Mn, biological materials, etc. trapped in sol-gel derived glass or ceramic composite microparticles Size, composition and shape-dependant properties of the nanoparticles are preserved For such applic...
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Highlights
Ultra clean, fast and environmentally friendly process for patterning metallic thin films For producing conducting wires for micro- / nano-electronics and bio-sensing applications Simulation demonstrated production of conducting wires at widths of less than 50 nm can be obtained over a...
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A homogeneous population of fully double stranded nucleic acid molecules having blunt ends, each of the molecules being at least 100 base pairs long, and having the same repetitive core sequence selected from the group consisting of mono, di-, or tri-nucleotide, with the proviso that the repetitive ...
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Highlights
Electrical and chemical communication (functional linking) between cells such as neurons and the surfaces of substrates that are part of electronic devices Generic technology can serve as the basis for the construction of biomedical devices that can, for example, be used to link nerves...
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Highlights
Provides methods for the manufacture and use of core-heteroshell nanocrystals Covers the visible to near-infrared (NIR) ranges Leverages the layer-by-layer in-solution growth techniques Environmentally benign character makes them ideal for large-scale implementation and biological and ...
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Highlights
Provides a simple method of producing nanoparticles from nanoemulsions Improves on earlier methods dependent on expensive high-shear homogenizers Enhances the production rate of nanoparticles Can be used with heat-sensitive materials such as drugs, agrochemicals and cosmetically active...
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Highlights
Development of nanocrystals on a variety of surfaces such as the inner surface of a cylindrical microcavity, a planar surface, a waveguide, or optical cavity structure on a chip Lower threshold for lasing than spherical dots Leverages quantum confinement effect for development of broad...
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Objective
Develop and operate user-oriented analytical facilities Aid researchers from the University and external customers in performing a variety of characterization measurements Support multidisciplinary research and "hands-on" technological education at The Hebrew University Services provide...
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Highlights
Hybrid nanoparticles consisting of metal and semiconductor material produce efficient photocatalysts for chemical reactions, splitting water, decontamination and other applications Can be used to harness solar energy and generate hydrogen from splitting water or produce electrical ener...
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Highlights
Method for coating conducting surfaces with nanoparticles bearing functional materials May be used for coating medical implants, stents, and other medical devices The nanoparticles may be carriers for drugs, antibacterials, anti-corrosives and more New technology for preparing drug-elu...
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Highlights
Copper nanoparticles for ink-jet inks New, much lower cost than conventional silver-based inks Nanoparticle inks lower the costs of printed electronics by reducing the need for high-temperature processing and enabling less material to be used. Because lower temperatures are needed to c...
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Highlights
Novel method for producing polymer-coated DNA Precise control and flexibility of method enables fabrication of products for a wide variety of applications DNA biosensor developed with enhanced sensitivity Ongoing work to develop chemical sensors for specific compounds Our Innovation
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This technology is simulation software that predicts the formation of carbon nanoparticles during combustion process, in a chemically specific way. The code is a combination of methodologies that describe the soot formation process by accurately modeling the reactions taking place at different time...
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The area of microfluidics is developing with many new sensors, separation devices, drug delivery systems, and other small-scale and micro-scale fluidic devices. For many of these devices, there is a need to circulated or move fluid through macroscale and microscale channels. At very small scales, ...
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This invention involves the fabrication of sub micrometer to nanometer scale particles in large quantities. It makes use of the nucleation of solute molecules or atoms in a homogeneous solution. By controlling the nucleation at below critical size for growth, and subsequently brining the solution sy...
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Background
Microfluidics is behind the processing and manipulation of small (10-9 to 10-18 L) amounts of fluids, in channels with dimensions of tens to hundreds of microns. Microfluidic emulsification, for example, allows for the generation of droplets with precisely controlled composition, morph...
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Technology
This platform technology is based on new materials composed of core-shell spherical particles which can be organized in 3-D arrays, melting the shells and leaving the spherical cores suspended in a perfect lattice within a solid or porous matrix. A wide variety of different core/shell...
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Background
Researchers in nanotechnology require manipulators with a nanometer positioning resolution, micrometer motion range, high repeatability, and large force output (i.e. payload driving capability). Current manipulators are often too large for applications inside SEM (scanning electron mic...
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Background
Intelligent manipulation (e.g., grasping/gripping) of micro- and nanometer-sized objects requires the use of miniaturized micro grippers with integrated force sensors. Currently, mirco- and nano manipulation relies purely on visual feedback either from an optical microscope or an elect...
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In the field of bioaerosol detection, there is a distinct need for an inexpensive, low power, robust trigger used to alert inhabitants of an increase in aerosol activity, thereby allowing the triggering of more sophisticated systems to determine the source. The JHU/APL concept, similar to the ringin...
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Abstract:
Aerogel is the lightest and lowest-density solid known to exist, composed of up to 99.8 percent air. However, it can hold 500 to 4,000 times its weight in applied force. Aerogel is 39 percent more insulating than the best fiberglass insulation, but without proper care it can break or crum...
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Abstract:
NASA Langley Research Center is actively seeking partnerships and collaborations to commercialize its Templated Growth of Carbon Nanotubes technologies...
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Abstract:
NASA Langley Research Center is actively seeking partnerships to commercialize its Controlled Deposition and Alignment of Single Walled Carbon Nanotubes technology....
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Abstract:
Carbon nanotubes (CNTs) offer great potential for advanced sensing devices due to their unique electronic transport properties. However, a significant obstacle to the realization of practical CNT devices is the formation of controlled, reliable and reproducible CNT to metallic contacts. I...
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Abstract:
This invention synthesizes carbon nanotube/silica nanocomposites via a templating method to control carbon nanotube diameter. The carbon nanotubes are isolated by removing the silica framework. This invention could lead to a low-cost method for growing aligned carbon nanotubes with contro...
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U.S. Patent 7,233,034
Technology Description Nanostructures and methods for production thereof by phase separation during metal organic vapor-phase epitaxy (MOVPE). An embodiment of one of the methods may comprise providing a growth surface in a reaction chamber and introducing a first mixture ...
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U.S. Patent 7,233,034
Technology Description Nanostructures and methods for production thereof by phase separation during metal organic vapor-phase epitaxy (MOVPE). An embodiment of one of the methods may comprise providing a growth surface in a reaction chamber and introducing a first mixture ...
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Background Electrochromism is the phenomenon displayed when some type of matter reversibly changes color when a burst of charge is applied. Recent applications of electrochromic materials include electrochromic windows which darken when voltage is added and are transparent when voltage is taken away...
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Background Individual carbon nanotubes have already exhibited excellent properties such as high electrical conductivity, high Young's modulus and a high thermal conductivity. However, for practical applications, dense bundles of carbon nanotubes must be used. Vertically aligned dense carbon nanotube...
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Background While timing-related failures are becoming increasingly common in nanometer technologies, and the importance of delay testing is becoming apparent, performing at-speed delay tests is still a challenge due to the limitations on the clock frequencies that can be provided by external test eq...
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Background Based on prior work for development of angstrom-scale measurement standards for the semiconductor industry, this innovation has made significant advancements in the alignment and control for etching lines/channels in silicon and silicon-on-insulator (SOI) structures. Prior alignment and e...
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Self-assembling siloxane fabrication of extremely thin nanostructurally ordered, pinhole-free, ultra-high-capacitance/low leakage organic dielectrics has been achieved by Northwestern University scientists. These organic nanoinsulators can be efficiently integrated into large thin film transistor (T...
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Electric field poled polymers are currently used to fabricate organic based modulators. The present invention provides a chemical process, employing self-assembly molecules to create the electro active layer in organic based modulators,without electric field poled polymers. This affords greater devi...
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A “wet-chemical” process affording molecule-based electro-optic (EO) material refractive index tuning in self-assembled superlattice (SAS) organic structures. The process retains essential microstructural acentricity, without electric field poling. Application potential exists in a wide range of EO ...
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Northwestern researchers created a new family of designed molecular chromophores that afford acentric films essential to non-linear electro-optic applications. These novel materials exhibit excellent physical and non-linear optical properties for waveguiding modulator applications. Intermolecular hy...
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Researchers at Northwestern University have isolated a novel molecular motor molecule, Prestin, from outer hair cells (OHCs) of the mammalian cochlea. This unique biological motor is capable of direct, rapid, electro-mechanical conversion without dependence on ATP. The ability of this molecular moto...
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The invention is a set of methods that a supplier of nano-indentation systems can incorporate into its proprietary software. A new version of software could then provide existing and prospective customers with the unique capability to report elastic modulus and Poisson’s ratio for coatings and their...
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The “BioChip” invention electronically detects biomolecules and toxic agents. When a target species chemically binds to the surface of a tiny cantilever probe, the probe deflects and the BioChip electronically measures and reports that deflection. The BioChip presents the following advantages over c...
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INVENTION: Scientists at Northwestern have created surface-enhanced Raman biosensors for detection of in vivo and ex vivo analytes. In particular, the present invention provides a technology for the in vivo detection of blood glucose.>/p>
ADVANTAGES: A potentially faster, easier, and less pain...
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Northwestern University has developed a unique & advantageous way to fabricate an array of carbon nanotubes. The Northwestern invention can deposit a single carbon nanotube and obtain a highly oriented and particle-free carbon nanotube deposition. The invention is feasible for mass production.
T...
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The high-speed nano fountain pen continuously feeds ink to an array of tips that deposit ink on a surface. The high-speed nano fountain pen incorporates special dispensing nanotips with micro-channels to transport fluid from reservoirs to nanotips.
Improvements over existing technology include: ...
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Self-assembling siloxane fabrication of extremely thin nanostructurally ordered, pinhole-free, ultra-high-capacitance/low leakage organic dielectrics has been achieved by Northwestern University scientists. These organic nanoinsulators can be efficiently integrated into large thin film transistor (T...
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Northwestern researchers have created new wear-protective ultralow friction coating compositions, with reduced affinity for water adsorption, affording decreased surface friction in humid environments. The amorphous films are generated by conventional sputtering techniques on a variety of material s...
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The invention is an ultra-hard, ultra-sharp diamond probe and tip for applications such as AFM and Nano-Lithography. A single stage fabrication process integrates tip and probe chip body as a single contiguous piece of diamond. The invention’s advantages over currently available methods include:
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A facile top-down process for fabricating anisotropic mesoscale (100-300 nm) metallic pyramids, with nanoscale tips (radii of curvature < 2 nm), has been devised by Northwestern researchers. Mesoscale holes in a chromium film are used as an etch mask to fabricate pyramidal pits in a silicon substrat...
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A novel high throughput method for fabricating free-standing hole array films with precise dimensions and spacing has been developed by Northwestern researchers. Enhanced transmission and standing wave patterns are generated by coupling light to the subwavelength hole arrays using surface plasmon re...
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Northwestern researchers have developed processes to produce stable dispersions of graphite nanoplatelets in aqueous or organic media. The treated nanoplatelets can be distributed in various matrices affording unique composite materials with useful mechanical, electrical and chemical properties.
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Novel SAND organic dielectrics suitable for high-performance III-V semiconductor devices such as metal-insulator-semiconductor field effect transistors (MISFETs).
ADVANTAGE: New process for manipulating the complex GaAs surface chemistry and thin film organic dielectrics for III-V semiconductor d...
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Northwestern researchers have developed a substrate independent multifunctional surface modification affording adherent nanofilms on all natural and synthetic surfaces tested, including metals, oxides, semiconductors, polymers and ceramics. The nanofilm chemically combines with a wide range of organ...
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The invention is a ceramic composite design that mimics features of Mother of Pearl (“Nacre”) in order to increase ceramic toughness. Ceramic materials have many attractive engineering qualities such as stiffness, hardness, wear resistance, and resistance to high temperatures. The primary obstacle t...
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Multilayer tool coatings that generate, at elevated service temperatures, an oxidized lubricous material that reduces surface friction and the need for additional lubricant or cooling.
ADVANTAGES: Stable machine tool coatings suitable for high temperature operation with reduced or no lubricant.
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Novel graphene oxide paper material possessing unique structure with excellent mechanical properties and chemical tunability.
ADVANTAGE: Inexpensive paper-like material with superior physical properties compared to similar vermiculite, graphite foil and carbon nanotube materials.
SUMMARY: Inor...
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Transparent, conductive composite silica thin films produced by a sol gel process incorporating exfoliated graphene.
ADVANTAGE: Simple process to create conductive, highly transparent, robust thin films on variety of substrates versus current complex deposition techniques.
SUMMARY: Electricall...
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A system to effect field induced oxidation (FIO) nanopatterning of hydrogen passivated silicon surfaces with an atomic force microscope (AFM) controlled by laser irradiation.
ADVANTAGES: Local oxidation on H:Si(111) surfaces can be fully suppressed or activated by toggling a laser luminating a l...
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Cement compositions and processing to enhance mechanical strength and minimize nanoscale crack formation.
ADVANTAGE: Simple process suitable to existing cement fabrication with potential for significant property improvement.
SUMMARY: Most construction cements today are hydraulic, and generally...
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The simple semiconductor and dielectric film fabrication afford TFTs with properties suitable for a variety of higher performance applications
SUMMARY: Fabrication of high performance thin-film transistors (TFTs) by solution phase processes promise commercially viable, low-cost, large-area elec...
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Substrate independent multifunctional coatings adherent to a wide range of natural and synthetic materials including polymers, metals and oxides, providing adhesive properties without surface pretreatment. The coatings employ a simple layer by layer process for the surface attachment of organic and ...
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Well dispersed graphite-polymer nanocomposites with enhanced physical properties are readily produced with the continuous solid state shear pulverization (S3P) process.
ADVANTAGES: Graphite-polymer nanocomposites with superior properties versus identical melt extruded compositions are manufactur...
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A continuous, solventless, scalable process (S3P) in concert with melt mixing producing well-dispersed polymer/multiwall CNT nanocomposites.
ADVANTAGES: A scalable process to produce well dispersed polymer / carbon nanotube nanocomposites with enhanced thermal and mechanical properties
SUMMA...
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The invention is a low-cost, "maskless" photolithography method to produce highly uniform arrays of nanopillars and nanoholes over a large area. The invention has the following advantages over existing methods by which to form nanoholes and nanopillars:
Single Stage: The process is maskless Hig...
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An effective method for the spatially-controlled writing of embedded, optically transparent, electrically conducting oxide nanowires and other patterns via focused ion beam implantation into highly resistive transparent metal oxide thin films.
ADVANTAGES: Nanoscale, spatially-controlled doping o...
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The integrity of electrode/organic interfacial contact is crucial to the performance and stability of organic light-emitting diodes (OLEDs). This invention addresses the problem by employing a well defined self-assembly strategy that improves the ITO anode / hole transport layer (HTL) interface morp...
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Researchers at Northwestern University invented a process that significantly improves Blue polymer light emitting diode (PLED) performance, efficiency, and stability. Blue PLED devices generally require anode coating with a conductive polymer hole transport layer (HTL), which can adversely impact de...
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Northwestern University researchers invented a new hole transport system for polymer light emitting diodes (PLEDs) with negligible visible light absorption, stability to ITO, solvent resistance and tunable electronic properties.
ADVANTAGE: Superior PLED performance and efficiency is observed ve...
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The invention is a switchable nano-electromechanical system (NEMS) for memory applications. Whereas current nano-switches of this type can “stick” irreversibly in the lower (closed position), the invention is stable in both switch positions – top and bottom. For this invention, a carbon nanotube (CN...
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An advanced cryogenic variable temperature ultrahigh vacuum (UHV) scanning tunneling microscope (STM) has been developed at Northwestern University. Incorporation of a new design and materials provides a robust instrument capable of high atomic resolution at 8.2 to 300 K, critical for single molecul...
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A conductive atomic force microscopy (cAFM) adjunct has been developed by Northwestern scientists that is capable of quantitatively measuring the magnitude and phase of alternating current flow through the tip/sample junction with a five order of magnitude improvement in sensitivity. Significant imp...
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An atomic force photovoltaic microscope (AFPM) has been developed to characterize spatially localized inhomogeneities in organic photovoltaic (OPV) devices. A biased conductive atomic force microscopy (cAFM) probe is raster-scanned over an array of illuminated solar cells enabling the determination ...
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The simple semiconductor and dielectric film fabrication afford TFTs with properties suitable for a variety of higher performance applications
SUMMARY: Fabrication of high performance thin-film transistors (TFTs) by solution phase processes promise commercially viable, low-cost, large-area elec...
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This invention presents a new route to the fabrication of multilayer heterojunction devices useful for large and small, multicolored display applications by means of molecular self-assembly techniques. The technology addresses major coating issues in organic light-emitting diode (OLED) construction,...
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Consumers operate numerous devices and machines to assist in daily activities. This requires some form of contact with an interface sensor as to translate the human intent into an electronic response. Typical interface or input sensors range from simple push buttons to highly sensitive strain gauge ...
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Northwestern´’´s Thin Membrane Transducer (TMT) invention is an ultra sensitive biosensor. The TMT has significant advantages over the cantilevered biosensor – another approach that has been previously implemented:
Highly Sensitive: The TMT detection sensitivity is on the order of a picomolar (1...
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The “BioChip” invention electronically detects biomolecules and toxic agents. When a target species chemically binds to the surface of a tiny cantilever probe, the probe deflects and the BioChip electronically measures and reports that deflection. The BioChip presents the following advantages over c...
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The invention is a low power light assisted sensor to detect Volatile Organic Compounds (VOC’s).
BACKGROUND: Metal oxide gas sensors must normally operate at high temperatures. This is undesirable in applications where safety and power consumption are primary concerns. Moreover, sensors operati...
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NanoNose™ is a software tool developed in LabView to enable rapid prototyping, test and evaluation of high-density sensor arrays. NanoNose™ characterizes sensors by exercising them through varied ambient conditions, concentration levels and flow rates. NanoNose™ is currently used for gases and gas m...
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The invention is a revolutionary approach which provides non-invasive nanoscale imaging capabilities for deeply buried and embedded structures in physical sciences, engineering systems as well as biological structures under physiologically viable conditions. The invention has operated in near-contac...
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The Johns Hopkins University seeks a partner to commercialize a new technique for fabricating Magnetoresistive Random Access Memory (MRAM). The fabrication method creates asymmetric ferromagnetic nanorings, a novel nanotechnology with unique properties. The nanorings form the basis for MRAM chips t...
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In the present invention, nanowires are fabricated by electrodeposition using semi-metallic bismuth. In this novel form of nanowire, positive magnetoresistance (MR) as high as 300% at low temperatures and 70% at room temperature, with a quasi-linear field dependence has been achieved. The MR effect ...
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Advantages Robust method for producing SWNT arrays with high aspect ratios High Yields Filament length and diameter can be controlled by changes in growth conditions Aligned SWNT arrays impart improved properties to composite materials Minimum post-growth processing required
The Technology ...
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The invention is a micro-machined device that can be used, in conjunction with a quantitative nanoindenter, to perform ex situ or in situ nano-mechanical testing experiments within an SEM or TEM chamber. The device, and the technique in general, can perform nano-mechanical characterization of 1-dime...
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This technology is a new synthetic method for manufacturing MCMNP. MNMNP are an enabling component of optical spectroscopic techniques, which are currently limited because of their relative susceptibility to spectral interference from chemicals present in the sample matrix and/or from low detection ...
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As a result of advanced printing ink technology, invisible inks have found a new venue in business and commerce as a means of protection against fraud, counterfeiting, and theft. The most useful inks are those that are invisible after printing, but which can be made visible through various means to ...
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In the treatment of osteoporosis and other bone disorders, it is desirable to deliver therapeutic compounds to the bone. However, it is known that certain substances, although therapeutic, are too toxic to be transported in the human body in free form. For example, fluoride anion (F–) is known to be...
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Large-scale production of tetrapodal CdSe nanoparticles Advantages . Method produces tetrapodal CdSe nanoparticles of uniform size with high selectivity . Production costs (relative to existing methods) reduced approximately 200-fold . Method does not require use of highly toxic alkyl phosphonat...
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This technology describes novel, comprehensive techniques for efficient synthesis of monodisperse, consistently-shaped and uniform-sized II-VI Compound Semiconductor (CS) nanoparticles like ZnSe & CdSe. Different shaped nanocrystals constitute an im portant research tool in several emerging areas in...
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The invention describes a novel generic process to synthesize II-VI (ZnSe, CdSe, etc.) semiconductor nanocrystals of uniform size by bubbling a gas through a preprepared colloidal suspension. The several bubbles formed are of uniform size and functio n as nanoreactor receptacles in which the nanocry...
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This technology describes the synthesis of 19F containing silica nanoparticles for 19F-Magnetic Resonance Spectroscopy and Imaging applications, an area marked by requirement and paucity of non-toxic fluorine-containing compounds that can administere d in sufficiently high quantities. The synthesis ...
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Proteins broken-up into peptide components (using proteolytic enzymes) are injected into mass spectrometers for analysis using Nano-Electrospray Ionization (Nano-ESI) techniques. During capillary electrophoresis, one of the most favored techniques in the ionization-spray phase, some portions of pept...
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The delivery of genetic material into living biological cells is currently done through several viral and non-viral techniques with their own unique sets of values and challenges. This invention describes a process to create surface amino-functionali zed ORMOSIL (organically modified silicate) nanop...
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Organic semiconductors are increasingly replacing silicon-based materials in many nanoimprinted integrated electronic and photonic devices such as flat-panel and flexible displays, solar cells, microsensors for medical devices, and the like. New deve lopments in these fields require substances that ...
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This technology describes novel, comprehensive techniques for efficient synthesis of monodisperse, consistently-shaped and uniform-sized II-VI Compound Semiconductor (CS) nanoparticles like ZnSe & CdSe. Different shaped nanocrystals constitute an im portant research tool in several emerging areas in...
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Most state-of-the-art solution based techniques to synthesize uniformly sized and distributed nanoparticles use reduction reactions of metal ions consisting of multiple complex steps that use organic solvents, produce undesirable by-products and requ ire additives to protect and stabilize the colloi...
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An earlier disclosure (technology no. 5824) revealed an in situ surfactant generation method to synthesize core semiconductor III – V nanocrystals (Indium Phosphide, Gallium Phosphide and Indium Arsenide). Those nanocrystals exhibited excellent surfa ce characterization and used a non-coordinating s...
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An earlier disclosure (technology no. 5824) revealed an in situ surfactant generation method to synthesize core semiconductor III – V nanocrystals (Indium Phosphide, Gallium Phosphide and Indium Arsenide). Those nanocrystals exhibited excellent surfa ce characterization and used a non-coordinating s...
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The invention describes a novel generic process to synthesize II-VI (ZnSe, CdSe, etc.) semiconductor nanocrystals of uniform size by bubbling a gas through a preprepared colloidal suspension. The several bubbles formed are of uniform size and functio n as nanoreactor receptacles in which the nanocry...
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The invention is a method of creating luminescent silicon nano particles. Particles as small as 3nm have been successfully prepared. These particles can be produced rapidly and economically. Moreover the process is very easy and highly efficient. The process is actually a two phase process wherein t...
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This invention describes the process to achieve a patterned growth of freestanding carbon nanotube(s) on submicron dot(s) on silicon by plasma enhanced hot filament chemical vapor deposition (PE-HF-CVD). Using this method, devices requiring freestan ding vertical carbon nanotube(s) such as scanning ...
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This invention describes a novel way to make well-aligned carbon nanotubes on a variety of substrates such as Ni,Fe,Co, etc. - coated Si or glass at temperatures below 666 degrees C.
Good alignment is very important not only for fundamental rese arch but also for applications such as flat panel ...
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It’s a “Novel” method aimed to- a) Produce highly luminescent CdSe/CdS/ZnS Quantum Dots. b) Enable transfer of these Quantum Dots from Organic to Aqueous (Essential requirement for Bio Imaging, biosensors and other optoelectronic applications ) Phase with Colloidal and Optical stability intact
C...
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The present disclosure combines broad spectral access enabled by semiconductor nanocrystallites (different compositions and sizes having different band gaps) with enhanced carrier transport via high-mobility organic semiconductors, in a polymeric mat rix, to realize hybrid nanocomposite photodetecto...
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This technology describes a 3-phased process to synthesize luminescent silicon nanoparticles in different colors. 3nm to 15nm diameter nanoparticles are synthesized at a high-rate by laser decomposition of silane. Wet chemical etching is done using a combination of acids (HF and HNO3) resulting in r...
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This technology describes two methods to synthesize blue luminescent silicon nanoparticles. The first is a 3-phase process. In the first phase, laser decomposition of silane and wet chemical etching using a combination of acids (HF and HNO3) yields photoluminescent nanoparticles of diameter 10-15 nm...
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This technology explains the formulation of a nanosized drug delivery carrier and the method of delivering photodynamic drugs, which are free from the external agents. From the results obtained for significant photosensitizing efficacy in vitro and in vivo conditions, it is believed that upon admin...
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Photodynamic therapy (PDT), following health agency approvals throughout the world for various cancers and other diseases, is slowly being accepted as a standard treatment for the treatment of obstructive esophageal and lung cancers as well as e arly stage lung cancer, and actinic keratoses. However...
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Using a rational design strategy, compositions (LINAP) have been developed for the targeted delivery of cancer vaccine antigens. Designed to target Dendritic cells (DC), LINAP is able to facilitate more potent T-cell immune responses than immunizing with antigens alone. In addition, LINAP confers st...
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Introduction Lower limb complications associated with diabetes include the development of plantar ulcers that can lead to infection and subsequent amputation. Several authors have postulated that shear stress is an important component of ulcer development. While it is known from force plate analyses...
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Summary Developed at Harvard Medical School, this invention provides nucleic acid arrays specifically designed for the assay of DNA-dependent protein:protein binding and/or physical interactions between proteins and nucleic acid molecules. Intermolecular analyses enabled by this technology are advan...
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Summary Colloidosomes are spherical shells of micron-sized particles made by the simple technique of self-assembly onto emulsion droplets. These hollow, elastic capsules are ideal for efficiently encapsulating active agents for selective and timed release because they are highly controllable in stre...
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Summary This invention concerns devices and methodology to control the positioning and movement of magnetic and non-magnetic nanoparticles in a fluid with nanometer precision. The devices allow for the independent and simultaneous control of many particles. The devices utilize a grid of current carr...
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Summary Signal intensities between samples on a microarrary typically vary by as much as three to four orders of magnitude, frustrating efforts at comparative analysis of samples assayed in parallel. At any given laser power or photomultiplier tube gain (PMTG), some signals will be below detection t...
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Summary This invention describes a microfluidic electro-flow focusing device. The essence of the device is the application of an electric field at a flow focusing junction between two immiscible fluids. The electric field creates charged drops and large forces necessary for emulsification, while the...
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Summary The invention is a microfluidic device for focusing and/or breaking fluid sections and drops. The subject fluid flows in the device's central channel as the dispersing fluid flows in the two outer channels. The outer fluid exerts pressure and viscous stresses that focus the inner fluid into ...
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Summary The invention consists of means of charging droplets and then using that charge to choose which channel a droplet will enter at a bifurcation.
There is a need to have fast, accurate means of precisely sorting and directing materials in an automated way on a microfluidic device. Examples o...
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Summary Everyday emulsions have drops of one liquid dispersed in an immiscible continuous liquid. A multiple emulsion has immiscible droplets dispersed in drops dispersed in an immiscible continuous liquid (double emulsion). The IP describes a simple apparatus that can make multiple emulsions with a...
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Summary The invention enables multiplex gene synthesis in a single reaction, using very low concentrations of oligonucleotides. The method, which employs a unique temporary tagging strategy, offers significant advantages in terms of speed and economy over existing methods for building genes, and eve...
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Summary Foundational work of Dr. George Church has enabled the production and use of replicable arrays of polymerase-amplified nucleic acid colonies (so-called "polonies") on semisolid support matrices (see Harvard Case No. 1438). The present invention extends the polony technology to provided minia...
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Summary Scientists encounter difficult obstacles in attempting to develop vaccines against malaria. For example, malaria parasites of the same species but isolated from different geographic locations may be genetically and immunologically distinct, so vaccines that protect against one geographic iso...
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Summary The invention constitutes microfluidic methods of forming particles that are substantially monodisperse. The technology builds on the technology disclosed in Harvard Case: 2215 – "Method and Apparatus for Fluid Dispersion", which creates monodisperse fluid droplets in a microfluidic flow f...
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Summary Background:
Colloidal particles absorbed on liquid interfaces have long been reported to stabilize emulsions and foams. Recently, individual droplets densely covered with small particles have been proposed as a possible means of obtaining a variety of composite particles and hollow locked...
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Summary Micro- and nanofabricated rotation and translation devices usually rely on the possibility to support the moving part on small dimples in order to reduce the contact area with the substrate. Nonetheless, large forces must be applied to overcome the residual friction. Furthermore, results lar...
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Background:
The development and application of microfluidic systems have increased dramatically in recent years. The systems that typically involve controlled fluid flow through a number of microfluidic channels can provide unique platforms useful in both research and production. Flow through a m...
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Summary Background Optical antennas are single or coupled metallic nanoparticles in which optical excitation of surface plasmons can produce very high intensities in the optical near field. The field enhancement relative to the incident field is maximum when the wavelength is suitably matched to the...
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Summary Differential scanning calorimetry (DSC) is a primary technique for measuring the thermal properties of materials. A typical DSC system requires relatively large amounts of test material, making thermal measurements on nano-scale samples difficult if not impossible. Thus, while traditional DS...
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Summary Emulsions—dispersions of two immiscible fluids—have many applications in industry and everyday life. These range from paints, to crop protection, chemical synthesis, and production of latices. They are also increasingly attractive for analytical applications. Traditional emulsions consis...
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Summary Creating Nano-Wrinkles of Virtually any Design on the Surface of Polymers
Elevator pitch: A new method has been developed at Harvard to design and create virtually any type of nano-wrinkle patterns on the surfaces of polymers. Anticipated applications for these hard-skin nano-wrinkled s...
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Summary Background:
Non-spherical colloidal particles are useful in advanced applications beyond those that regular spherical colloidal particles exhibit. For example they are useful for modifying optical properties, controlling suspension rheology, and engineering colloidal composites. However c...
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Summary The need: Corrosion of metals hamper the performance and safety of products ranging from medical implants to large-scale naval vessels, aircraft, bridges, and oil pipeline structures. A 2002 study of the US Federal Highway Administration estimated the cost of corrosion of metallic materials ...
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Summary Since they were first demonstrated over twenty years ago, optical tweezers have been widely used for the manipulation and measurement of many microscale particles, particularly in the biological sciences. However, many of these systems require large, high-powered laser systems along with bul...
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Summary This invention describes a method to directly write optical elements in three dimensions inside a transparent material using an unamplified femtosecond laser. Ultrashort pulses from a laser oscillator are tightly focused into the material, causing localized heating and subsequently producing...
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Summary Colloidosomes are spherical shells of micron-sized particles made by the simple technique of self-assembly onto emulsion droplets. These hollow, elastic capsules are ideal for efficiently encapsulating active agents for selective and timed release because they are highly controllable in stre...
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Summary This invention concerns devices and methodology to control the positioning and movement of magnetic and non-magnetic nanoparticles in a fluid with nanometer precision. The devices allow for the independent and simultaneous control of many particles. The devices utilize a grid of current carr...
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Summary This invention provides a one step process for reading magnetic data and converting the magnetic digital signal directly into an optical signal. This invention enables an electronic system, which includes a three terminal device having a light emitting portion and a magnetically sensitive po...
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Summary This invention describes a microfluidic electro-flow focusing device. The essence of the device is the application of an electric field at a flow focusing junction between two immiscible fluids. The electric field creates charged drops and large forces necessary for emulsification, while the...
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Summary The invention provides methods for rapid fabrication and use of replicable, high-density nucleic acid arrays. Array features are produced through amplification on a support matrix of nucleic acid templates of interest. A significant advance over conventional DNA array technologies, the so-ca...
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Summary Developed at Harvard Medical School, this invention provides nucleic acid arrays specifically designed for the assay of DNA-dependent protein:protein binding and/or physical interactions between proteins and nucleic acid molecules. Intermolecular analyses enabled by this technology are advan...
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Summary Signal intensities between samples on a microarrary typically vary by as much as three to four orders of magnitude, frustrating efforts at comparative analysis of samples assayed in parallel. At any given laser power or photomultiplier tube gain (PMTG), some signals will be below detection t...
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Summary Foundational work of Dr. George Church has enabled the production and use of replicable arrays of polymerase-amplified nucleic acid colonies (so-called "polonies") on semisolid support matrices (see Harvard Case No. 1438). The present invention extends the polony technology to provided minia...
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Summary The invention comprises a novel method and an apparatus to manipulate, segregate, detect and analyze biological samples on a microfluidic CMOS chip. This technique offers sub-micrometer precision and fast processing speeds for a cheap, easily accessible lab-on-a-chip system. The technology i...
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Summary Background:
The development and application of microfluidic systems have increased dramatically in recent years. The systems that typically involve controlled fluid flow through a number of microfluidic channels can provide unique platforms useful in both research and production. Flow thr...
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Summary This is a fluidic all-optical switch that alters the path of a light beam by controlling the geometry of a reflective surface that is defined by the interface between two fluids. The device has also been described as a "deformable mirror," since it employs conducting polymers and fluids.
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Summary This invention concerns devices and methodology to control the positioning and movement of magnetic and non-magnetic nanoparticles in a fluid with nanometer precision. The devices allow for the independent and simultaneous control of many particles. The devices utilize a grid of current carr...
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Summary Micro- and nanofabricated rotation and translation devices usually rely on the possibility to support the moving part on small dimples in order to reduce the contact area with the substrate. Nonetheless, large forces must be applied to overcome the residual friction. Furthermore, results lar...
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Introduction Caged compounds are biologically active molecules rendered inactive by a link to a chemical group (the "cage") through a photolabile bond. They are useful in the study of the spatiotemporal dynamics of cellular systems. Currently used caged molecules can only be photoactivated in the UV...
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Introduction Organic functional materials offer advantages relative to their inorganic analogs including mechanical flexibility and inexpensive fabrication. Similarly, nanoimprint lithography (NIL)
has made much progress as an alternative to conventional photolithography that can provide the same p...
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Introduction Nanomaterials possess unique qualities (e.g. strength, lightweight) that make them desirable for numerous applications. Hybrid structures combine two or more materials to give the final structure qualities of both component materials. By using an electric field in conjunction with capil...
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Automatic handling of porous and soft materials The Norwegian University of Science and Technology (NTNU) is actively seeking companies to license an exciting novel gripping technology for robotic applications. The Coanda gripper opens new opportunities and enables increased quality and cost reducti...
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Research into CO2 technology is receiving increased attention due to the rapid increase in concentration the last 100 years, and the problems that it may cause for our environment. This technology is developed to clean biogas to reach fuel quality, but can be used for virtually any CO2 separation pr...
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Production of hydrogen from natural gas sources (methane) is energy consuming and this technology enables the manufacturing of a sorbent material that has the potential to reduce this energy cost by 10 – 30% depending on process (PSA, SESMR).
The material has applications for other areas as long ...
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Research into CO2 technology is receiving increased attention due to the rapid increase in concentration the last 100 years, and the problems that it may cause for our environment. This technology is developed to clean combustion gases of CO2 so that it can be stored or used for enhanced oil recover...
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Recycling of aluminium is highly energy efficient compared to making virgin metal, but still the recycling process can be improved upon. By avoiding the problems related to melting of scrap aluminium, even more energy can be saved and more material can be recycled (less loss to oxidation).
DESCRI...
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In the field of medical systems, removing CO2 contributes to a more effective recycling of anaesthesia gas, thereby reducing costs and improving the working environment in the operating room. Gas separation membranes offer a more cost-efficient and less complex alternative to traditional gas separat...
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Introduction The impact of metal nanostructures is continually increasing as we become more capable of producing them with well-controlled sizes and shapes for fine-tuning their properties and further development of emerging applications. Silver has been one of the most studied materials for nanostr...
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Introduction There is a need in the medical industry for cost-effective, non-invasive methods of sampling biological fluids that often contain bio-markers such as nucleic acids, which can be indicative of disease states; thus, sensitive and specific diagnostic tests to locate bio-markers are needed....
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Introduction Non-invasive manipulation of micro- and nano-scale objects with rotational capability is attractive for various biomedical applications such as constructing biofims, human tissue engineering, and in vitro fertilization. The technology is also uselful for nano-fabrication such as alignin...
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Introduction Fabrication of structures at dimensions below 45 nanometers (nm) is a challenge facing commercial semiconductor and emerging nanofluidic devices. The ability to create nanochannels, nanowires, nanodots, and nanogaps will open up a new generation of components for electronic and biotechn...
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PPLICATIONS OF TECHNOLOGY:
Micromachining of sensors, detectors and actuators Quantum devices Heat sinks High aspect ratio lithography Medically implanted and surgical devices and sensors Non-destructive microcircuit inspection Packaging and integration of miniaturized components
ADVANTAGES:
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APPLICATIONS OF TECHNOLOGY:
Detection of contamination in semiconductor processing Detection of liquid films affecting wetting and adhesion on surfaces Imaging of liquids interacting with organic material in biological systems Characterization of biomaterials:
o Hydrophilic and hydrophobic r...
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APPLICATIONS:
High throughput and high content nanotoxicity screening Discovering new nanotoxicology profiles and new targets for nanotherapy Nanomaterial toxigenomics and high content imaging analysis
ADVANTAGES :
Minimizes the need for expensive and controversial animal studies Enables ra...
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APPLICATIONS OF TECHNOLOGY:
Early stage screening of cancers via detection of proteases and proteolytic activity in fluid or biopsy samples Prostate cancer detection, and possibly the detection of other protease-related cancers such as breast, colon, kidney, skin, stomach, ovary, and lung cancer ...
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APPLICATIONS OF TECHNOLOGY:
Ultra-sensitive biological and chemical sensing Microchips Catalysis Nanocomputing and nanoelectronics
ADVANTAGES:
Uses standard semiconductor fabrication equipment and techniques to produce nanosize semiconductors on a wafer scale
Produces smaller feature siz...
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APPLICATIONS OF TECHNOLOGY:
Precise cutting and tailoring of small scale structures and devices Tailoring nanostructures/nanomaterials to create field emitters, quantum dots, nanoscale resonators, electrical interconnects and circuitry, linear and rotational bearings, NEM/MEMS components, sca...
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APPLICATIONS OF TECHNOLOGY:
Generating defect-free nanotubes or nanowires with superior mechanical, thermal, and electrical properties for devices such as MEMS/NEMS, ICs, and resistors, as well as for ultimate-strength materials Creating sophisticated heterojunctions in a MWNT by refining specifi...
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APPLICATIONS OF TECHNOLOGY:
Manufacturing MEMS and NEMS devices, e.g. arrays, solar collectors, nanoscale memory and optical switching devices, field emitters, chemical or mass sensors, LEDs, flexible interconnects, mechanical filters, microfluidic pumps and gates
ADVANTAGES:
Allows precis...
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APPLICATIONS OF TECHNOLOGY:
Manufacturing MEMS and NEMS devices, e.g. arrays, solar collectors, nanoscale memory and optical switching devices, field emitters, chemical or mass sensors, LEDs, flexible interconnects, mechanical filters, microfluidic pumps and gates
ADVANTAGES:
Allows precis...
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Drug delivery to tumors with increased LDL-cholesterol requirements and LDL receptor activity, including: brain, colon, prostrate, liver, lung, adrenal, hormone unresponsive breast, leukemia
ADVANTAGES:
Targets the LDL receptor for selective drug delivery and entry into the lysosome Contains m...
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APPLICATIONS OF TECHNOLOGY:
High-contrast electron microscopy, especially for radiation-sensitive materials and weak phase objects like:
whole-mount subcellular organelles and thin areas of whole cells isolated biological macromolecules thin crystals thin sections of cells and tissues Single-par...
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APPLICATIONS OF TECHNOLOGY:
Thermal management of small devices and systems, whether semiconductor electronics, nanofluidics, or photovoltaics Design, prototyping and characterization of new circuit models High-resolution measurement at extreme temperatures
ADVANTAGES:
Does not interfere wi...
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APPLICATIONS OF TECHNOLOGY:
Solid-based storage and capture of hydrogen, carbon dioxide or other gases
ADVANTAGES:
Promises higher storage capacity than carbon materials, better environmental stability than metal-organic, and faster kinetics than direct use of metal hydrides Demonstrated fabric...
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APPLICATION OF TECHNOLOGY:
Organic/nanomaterial hybrid solar cells
ADVANTAGES:
Introduces a new parameter for controlling solar cell morphology Improves conversion efficiency by increasing mobility and photon absorption and reducing electron/hole recombination
DESCRIPTION:
In order to attai...
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APPLICATIONS OF TECHNOLOGY:
Biological imaging Electronics production Catalyst production Photovoltaics LCDs Photonic band gap materials Mechanical structural support in polymer films High-surface-area catalysts
ADVANTAGES:
Can synthesize whole branched inorganic nanocrystals with well-defi...
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Berkeley Lab researchers have developed two approaches for increasing the charge efficiencies of electrodes used to produce flexible organic light emitting diodes (OLEDs) and solar cells. Both approaches will reduce manufacturing and packaging costs. These technologies have patents pending and are ...
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APPLICATIONS OF TECHNOLOGY:
- Thermal management of small devices and systems, whether semiconductor electronics, nanofluidics, or photovoltaics - Design, prototyping and characterization of new circuit models - High-resolution measurement at extreme temperatures
ADVANTAGES:
- Does not interfer...
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APPLICATIONS OF TECHNOLOGY:
Filter or amplifier for microwave frequency and RF electronics, e.g. cell phones, personal music devices Mass sensor
ADVANTAGES:
- Frequencies over 4 GHz - Operates at ambient temperatures and pressures without significant loss of resonance quality - Individually tun...
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APPLICATIONS OF TECHNOLOGY:
- All-in-one radio receiver for cell phones/wireless networks/GPS and other electronic devices - Radio controlled devices that can exist inside the body, e.g. used as drug release triggers, diagnostic instrumentation, interfacing with muscle or brain function - Ultra sma...
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APPLICATIONS OF TECHNOLOGY:
- Mechanical reinforcements and composites, e.g. cell phone cases, structural elements of aircraft - Batteries, supercapacitors - Fuel cell components - Transistors, biosensors - Field emission sources - Electronic circuits - Scaffolds for novel chemistries - Deep ultr...
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APPLICATIONS OF TECHNOLOGY:
- Electronic and thermal circuit design and operation - Solar energy collection - Heat pumps and internal combustion engines - Hybrid biological/inorganic systems - Phononic information processing - Energy-efficient buildings and appliances, such as refrigerators
AD...
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IB-1910
APPLICATIONS OF TECHNOLOGY:
• Understanding the dynamic changes in the microstructure of thin films as a function of biaxial strain
• Inducing biaxial strain in thin films for failure analysis
• Improving the reliability and performance of devices such as microactuators, biological mi...
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IB-2501, 2502
APPLICATIONS OF TECHNOLOGY:
• Using electron-beam induced deposition (EBID) on graphene membranes to create nano-scale doping patterns for electronic circuits lithography etch masks diffraction gratings (for monochromators, spectrometers, wavelength division multiplexing devices, ...
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JIB-2121
APPLICATIONS OF TECHNOLOGY:
Nanoscale fabrication and manufacturing of:
• Medical micro- and nano-devices including components for implants
• Materials and structures for microelectronics and optoelectronics
• Contacts, circuit lines, interconnects, and integrated circuits for semic...
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IB-2374
APPLICATIONS OF TECHNOLOGY:
• Removes soluble nanoparticles from water by aggregation and precipitation in solution
• Can be used to clean up metal, metal oxide, and semiconductor nanoparticles
• Inhibits growth of organisms in wastewater
• Provides a means for assessing the toxicity...
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IB-2419
APPLICATIONS OF TECHNOLOGY:
• Determining the toxicity and biological effects of nanoparticles
• Assessing health, occupational, and environmental risks of nanomaterials
• Establishing safety standards for the use of nanomaterials in biomedical and clinical applications
• Fine-tun...
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IB-2323, IB-2333
APPLICATIONS OF TECHNOLOGY:
Transfection of foreign molecular-scale cargoes into cells (e.g. DNA, RNA, polymers, dendrimers, nanoparticles, etc.)
Insertion of probes into cells to observe physical and biochemical interactions. (e.g. quantum dots-probes)
ADVANTAGES:
Unlike...
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Abstract
This invention provides a heat dissipation structure for use in optoelectronic devices. More specifically, this technology is an innovative heat dissipation thick/thin organic-inorganic coating containing active molecularly functionalized vibrational lattice modes designed to act as a mol...
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Palladium nanoparticle and polymer matrix catalyst that exhibits high substrate conversion and stability
TECH FIELD(S)
Palladium metal catalyst invention
FEATURES
Pd catalysts are used in the hydrogenation and oxidation of many industrial products. For example, Linalool (LN), a fragrance ...
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New Market Opportunity:
Silver nanoparticles have applications in a wide number of fields across the electronics, physics, chemistry and biomedical fields. The optical absorption and fluorescence characteristics of the silver nanoparticles are critical to their functionality in all applications. Th...
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