Respiratory Detection System (RDS)
Introduction Respiration rates are an important indicator of cellular and metabolic states in cells ranging from mammalian to bacterial, from individuals to large populations. Unfortunately, conventional techniques have significant drawbacks: for instance, electrochemical techniques have low sensitivity and consume oxygen and optical techniques are difficult to integrate. With more effective monitoring techniques, the detection of microorganisms, the characterization of disease states, and the characterization of cellular processes and perturbed systems will be greatly enhanced. Technology Description Professor Burgess at the University of Washington has developed a fast and simple technique for directly measuring respiration rate of a variety of cells based on a molecular oxygen sensor. Measurements using this device do not perturb, stress, or contaminate cells and do not suffer from drift. The system has a high sensitivity and results are obtained within minutes. Business Opportunity The ability to easily and rapidly measure respiration rates presents opportunities for monitoring and evaluating a wide variety of cells, including attached or unattached mammalian cells and bacterial cells, single cells and large populations. As a gauge of cellular health, this is important in diagnostics, screening, and drug development. Additional applications include environmental sampling, such as for monitoring the quality of water and wastewater. Stage of Development A working prototype of the device has been developed. Intellectual Property Position The UW has patents pending on this technology.
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