Tailored Pins for High Density Microarray Production

Chemical sensor arrays are low cost, compact, robust and versatile alternatives to large analytical tools and hence drive the need to rapidly fabricate reusable chemical sensor arrays for simultaneous multi-analyte quantification.

This invention includes the rapid fabrication of reusable chemical sensor arrays for simultaneous multi-analyte quantification by machining a novel array of minature spherical sensor sensor dots atop an LED. The array can be specifically tailored for any known cla ss of analytes. LED's provide an inexpensive sensor light source, low power consumption, and automated, customizable fabrication procedure. LEDs have a very long lifetime (>10,000 hrs) are physically robust (solid state) and can be computer contr led for unattended operation. Novel porous chemical xerogels with recognition chemicals (luminophores sequestered within) form the dots. Additionally, an important goal in sensor microarray design is developing tools to decrease the feature size and inc rease the array element density. This invention reduces sizes and improves natures of the printed dots through better pin materials and structures. It is a new two part pin system (a metallic or polymeric pin mount with a tailored pin) which can be easily retrofitted to existing robotic pin printers. The pin is non-metallic (optical fibers, glass, quartz/polymer precision rods) and could contain a channel.

The specific advantages are:

a)The system can produce features of the order of l

Categories: Sensors, Screening

Type of Offer: Licensing

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