Diversified Chemical Responses from a Single Chemical Sensor

Chemical sensor arrays are low cost, compact, robust and versatile alternatives to large analytical tools and hence drive the need to rapidly fabricate reusable chemical sensor arrays for simultaneous multi-analyte quantification.

This invention includes the rapid fabrication of reusable chemical sensor arrays for simultaneous multi-analyte quantification by machining a novel array of minature spherical sensor dots atop an LED. The array can be specifically tailored for any known class of a nalytes. LED's provide an inexpensive sensor light source, low power consumption, and automated, customizable fabrication procedure. LEDs have a very long lifetime (>10,000 hrs) are physically robust (solid state) and can be computer controlled f unattended operation. Novel porous chemical xerogels with recognition chemicals (luminophores sequestered within) form the dots. Additionally, diversification (many sensors, with different luminophores for one analyte) provides greater accuracy. This invention provides diversification with one sensor dot by placing different luminophores within it. A modulated excitation source creates distinctive color change profiles from an analyte sample through phase differentiation techniques and mathematical manip ulation of the reaction kinetics equation. These different color profiles represent the same quantity of the analyte present and are computer processed to yield a more statistically accurate measure of the analyte quantity.

The main advantages (ov

Categories: Sensors, Screening

Type of Offer: Licensing

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