New GFT NMR Experiments for Complete Resonance Assignment of Proteins
This invention describes a set of new GFT NMR experiments for the assignment of backbone and side-chain resonances of proteins. The invention applies a Gaussian Matrix to the data acquisition and processing methods, creating the ability to adjust th e investments of NMR sampling time to the actual demands required to detect a signal with digital resolution simultaneously high. The resolution exceeds conventional FT NMR in most cases. A key advantage of this new breakthrough is the ability to o btain complete chemical shift assignment of proteins with high precision and short measurement times.
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