New Chiral Catalysts for use in enantioselective synthesis

A series of chiral dirhodium catalysts was previously developed and were found to be very effective in enantioselective transformation of donor/acceptor carbenoids (a class of intermediates). Though those catalysts have braod utility, they require t hat the acceptor group is a methyl ester for best results. The present invention is a group of new catalysts that have been found to be exceptional for a range of other acceptor groups thereby greatly enhancing the range of this chemistry.

Categories: Materials & Chemicals, Research Tool Patents Issues: 7,385,064

Type of Offer: Licensing

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