Development of a Novel Confocal Laser Scanning Microscope for Functional Recording of Fast Neuronal Activity

Dendrites of neurons in the central nervous system are the principal sites for excitatory synaptic input. These neuronal dendrites are known to possess active computational properties also. Currently, these properties are mainly studied using well-known �patch clamp� techniques. However, the small number of sites that can be simultaneously accessed limits this approach. The inventors have developed an imaging system that allows for high-speed, multi-site optical recording from single neurons in living brain tissue by combining acousto-optic (AO) beam deflection with addressable spatial filtering. This combination allows for fast random-access positioning (

Type of Offer: Licensing



« More Biotech Patents

---