Isolation of GRIP

The invention concerns the discovery of a novel family of proteins named as glutamate receptor interacting proteins (GRIPs). GRIPs interact with non-NMDA glutamate receptors and, in particular, interact selectively with the C-termini of AMPA glutamate receptors. A novel gene that encodes GRIP has been isolated and equenced. GRIPs appear to be involved in the targeting of membrane proteins that may have a critical role in neurotransmitter receptor functions, such as the formation and maintenance of excitatory synapses.

Patent (Set) 6,001,575;

Patents:
US 6,001,575

Inventor(s): Huganir, Richard

Type of Offer: Licensing



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