Mutational analysis of the tyrosine phosphatome in colorectal cancers
JHU researchers have performed a comprehensive mutational analysis of the protein tyrosine phosphatases super gene family in colorectal tumors and other cancers. It was discovered that the mutated tyrosine phosphatases are tumor suppressor genes, regulating pathways that may be amendable to therapeutic intervention Description (Set) Proposed Use (Set) Provides the basis for new therapeutic and diagnostic approaches for colorectal cancer. Patent (Set) WO2005/113824Inventor(s): Velculescu, Victor
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