Interventional Devices for Chronic Total Occlusion Recanalization Under MRI Guidance

Recanalization of chronic total occlusion (CTO) is a chanllenging clinical procedure traditionally conducted under x-ray guidance to improve blood flow to patients with symptomatic ischemia. X-ray guidance generally does not provide satisfactory imaging nor geometric information about the artrtial contours, and in the absence of a lumen to fill with radiographic contrast, the recanalization procedure is hazardous. Devices inadvertrntly can exit the native vascular lumen leading to perforation and hemorrhage. Because MRI provides excellent tissue contrast and tomographic information even without angiography, it is an attractive guidance modality for recanalization of CTO. Catheters and other interventional devices are visualized under MRI using passive and active tracking techniques. For devices to be accurately visualized and tracked in an MRI environment active tracking or visualization is the mode of choice. Typically in a clinical setting a guidewire and a catheter assembly is used to recanalize CTO lesions. Guidecatheter and guidewire designs with RF receiver coils built in them so as to enable visualization and tracking are presented in this disclosure. Description (Set) Proposed Use (Set) The devices described will enable various interventional vascular procedures.

Inventor(s): Karmarkar, Parag V.

Type of Offer: Licensing

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