MTAP KO Lines for Drug Discovery

Methylthioadenosine phosphorylase (MTAP) plays an important role in the salvage pathway for the synthesis of adenosine. The loss of MTAP function has been implicated in a variety of cancers. JHU researchers have created MTAP knock out cell lines. Description (Set) Proposed Use (Set) The cell lines described in this invention can be used in screens for novel molecules that target the deficiency of MTAP

Inventor(s): Vogelstein, Bert

Type of Offer: Licensing



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