The Transcriptome Interaction Database (TID): a Novel Bioinformatic Method and Software Package for Analysis of MicroRNA-mRNA Interactions and their Consequences

Researchers at JHU have developed the Transcriptome Interaction Database (TID), a centralized relational database and analysis toolset for combining microRNA (miRNA) data with large scale microarray mRNA data, to make predictions of miRNA-mRNA interactions in a given cell type. The TID uses a simplified and automated user interface to allow a researcher to efficiently make predictions concerning miRNA function within a cell population, or to compare miRNA expression and function among multiple cell populations. The current state-of-the-art enables researchers to achieve the same results only by manually and sequentially entering data into different software programs in a laborious manner. Description (Set) Proposed Use (Set) The TID software and method are widely applicable to scientists working with any source of mRNA and miRNA expression data. Therefore the software will be able to construct miRNA-mRNA target predictions and interactions for any cell type.

Inventor(s): Georgantas, Robert

Type of Offer: Licensing



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