New Method of Collecting Exhaled Breath Biomarkers at Room Temperature
Abstract (Set) A simple method of collecting biomarkers that is fast, simple, and accurate is important for both research investigations and clinical management. There is currently limited number of methods to obtain breath biomarkers noninvasively. This new method of biomarker collection though exhaled breath is easy, quick, and does not require cooling of the breath that previous methods of breath collection have required. This has the effect of increasing the stability of the collected biomarkers and does not involved dilution with water. The concentration of breath biomarkers will be normalized to the volume of carbon dioxide sampled during collection. Description (Set) Proposed Use (Set) This novel adaptation on breath collection will enable the collection of several different types of mediators from throughout the respiratory tract including adenosine, ammonia, hydrogen peroxide, isoprostanes, leukotrienes, nitrogen oxides, peptides and cytokines, and surfactant.
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