Real-Time Imaging and Monitoring of Laser-Tissue Interaction

Background In laser dermatological and oncology treatments, absorbed radiant energy generates an increase in temperature to heat targeted structures. However, before performing laser therapy, it is important to identify the appropriate laser dosimetry required to heat targeted structures and protect surrounding tissue structures while ensuring target tissue damage.

Invention Description This invention is a method and apparatus to guide and non-invasively monitor laser photothermal therapies. Researchers at The University of Texas at Austin have developed an approach to image and identify the tissue composition under therapy. Furthermore, during the laser therapy, the imaging technique provides real-time monitoring and can be used to generate temperature maps of the tissue.


Real time and noninvasive imaging during laser therapy Monitors temperature elevation during the procedure Provides feedback control during laser therapy Improves treatment planning through identification of tissue structures Increases skin safety and health


Single integrated probe for both imaging and therapy Thermal maps throughout the tissue region of interest Identification of skin-fat boundaries Real-time control in photothermal therapy Visualization of tissue structures

Market Potential/Applications The initial market segments include various applications with multi-million dollar market size: photothermal cancer therapy, laser fat reduction, hair removal, vascular therapy, port-wine stain removal, skin rejuvenation, skin tightening, skin remodeling, and tattoo removal.

Development Stage Lab/bench prototype

IP Status One PCT patent application filed

UT Researcher Thomas E. Milner, Ph.D., Biomedical Engineering, The University of Texas at Austin Stanislav Emelianov, Ph.D., Biomedical Engineering, The University of Texas at Austin Jignesh Shah, Biomedical Engineering, The University of Texas at Austin

Type of Offer: Licensing

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