Establishment of a Human Cerebral CortexCell Line

This invention consists of a continuous, non-malignant, neuronal cell line, the cells of which: a) in the undifferentiated form are essentially free of branched process; b) stain positively for neurofilament protein and neurotransmitters; c) do not stain positively for glial fibrillary acidic protein; and d) in the presence of nerve growth factor differentiate into cells with long branched processes. Derivative cell lines of such cell lines are also contemplated. The cell line is useful in the screening andevaluation of chemical and biological compounds.

Type of Offer: Licensing



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