Peptide Enhancing Plant Pathogen Resistance

Tech ID: 11175 / UC Case 2009-480-0

Full Description
Innate immunity is the first line of defense against pathogen attack. A plant or animal’s innate immune system is triggered only when its pathogen (or pattern) recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). While PRRs play a significant role in triggering innate immunity in plants and animals, the PAMPs recognized by the receptors have not been well characterized.

Researchers at the University of California, Davis have discovered a short peptide produced by a bacterial pathogen that induces rice innate immunity. Recognition of this peptide by the rice XA21 PRR triggers immunity to normal virulent pathogens.

Suggested uses
Because of the economic importance of cereal crops and the magnitude of disease-related losses, this discovery has significant applications in crop production and protection. By applying this peptide to leaves or seeds of cereals carrying the Xa21 gene as a protectant, the plant’s immunity to pathogens is triggered without the use of harmful pesticides, chemicals, or expensive protective treatments.

* Technology able to trigger bacterial and fungal immunity by simple exposure.
* Can be used as a seed or foliage treatment (e.g., by spraying seeds/leaves or dipping leaves). Easy application to plants.
* Peptide can be easily synthesized.
* Induces immunity without the use of chemicals, pesticides or transgenic plants.

* Patent Pending

Inventor(s): Han, Sang Wook; Lee, Sang Won; Ronald, Pamela C.

Type of Offer: Licensing

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