Polymer Micelle Complex Including Nucleic Acid

It is an object of the present invention to provide: a polyion complex that sufficiently retains a photosensitizing substance in serum and is excellent in terms of structural stability; a nucleic acid polyplex as a constituent thereof; and a device and a kit for delivering a nucleic acid into a cell. The nucleic acid polyplex of the present invention comprises a cationic polymer represented by general formula (1) and a nucleic acid. The polyion complex of the present invention comprises the nucleic acid polyplex of the present invention and an anionic photosensitizing substance.

The present invention relates to a polymer micelle complex that contains a nucleic acid and a photosensitizing substance, a device for delivering a nucleic acid into a cell, and a kit for delivering a nucleic acid into a cell. More specifically, the present invention relates to the aforementioned complex, device, and kit, which can be used for a method for photochemically introducing a nucleic acid into a target cell utilizing photodynamic therapy.

Patents:
US 20,090,018,216

Inventor(s): KATAOKA KAZUNORI [JP]; YAMASAKI YUICHI [JP]; NISHIYAMA NOBUHIRO [JP]; JANG WOO-DONG [JP]; ARNIDA ANWAR [JP]

Type of Offer: Sale



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