Methods of identifying modulators of CFTR/CK2 interaction

A method of identifying a compound capable of modulating CFTR/CK2 interaction and/or CFTR phosphorylation by CK2 comprising exposing CFTR and/or CK2 to a test compound and assessing the effect of the test compound on CFTR/CK2 interaction and/or CFTR phosphorylation by CK2. A method of screening for compounds of use in preventing or treating a secretory state or disorder and/or a cancer and/or cystic fibrosis wherein CFTR and/or CK2 is exposed to a test compound and the effect of the test compound on CFTR/CK2 interaction and/or CFTR phosphorylation by CK2 is assessed.

Attached files:
GB 2437681.jpg

Patents:
GB 2,437,681

Inventor(s): MEHTA ANIL [GB]; CRAWFORD RUSSELL [GB]; TREHARNE KATHRYN

Type of Offer: Sale



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