Formation of 18F and 19F Fluoroarenes Bearing Reactive Functionalities

An iodonium compound of formula (I): where RAR1 is a C5-6 aryl group, bearing at least one substituent selected from formyl, thionoacyl, acylamidocarboxy, thionoester, azo, C2-20 alkenyl, C2-20 alkynyl, and (CH2)nRc, where Rc is selected from ether, amino, azo and thioether; RAR2 is a C5 heteroaryl group, optionally substituted by one or more groups selected from C1-12 alkyl, C5-12 aryl, C3-12 heterocyclyl, ether, thioether, nitro, cyano and halo, and may be linked to a solid support or fluorous tag; and X is a counteranion.

Attached files:
WO 2009138763.jpg

Patents:
WO 2,009,138,763   [MORE INFO]

Inventor(s): CARROLL MICHAEL ANDREW [GB]; YAN RAN [GB]

Type of Offer: Sale



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