PATENTS
For Sale or License

Crowdsell Your Patent

Notify me of New Entries

Receive an email whenever a new patent is added.
You can unsubscribe at any time.



Sort by category

Subunit Selective NMDA Receptor Potentiators for the Treatment of Neurological Conditions

Provided are compounds, pharmaceutical compositions and methods of treating or preventing disorders associated with NMDA receptor activity, including schizophrenia, Parkinson's disease, cognitive disorders, depression, neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologi
...

Display of Patient-specific Data

Systems, methods, and computer-program products identify clinical data corresponding to a plurality of patients located within a common health care delivery unit, and apply one or more rules to at least some of the clinical data using at least one quality and/or safety measure-specific specification
...

Compounds, Compositions, Methods of Synthesis, and Methods of Treatment

Briefly described, embodiments of this disclosure include compounds as described herein, labeled compounds as described herein, pharmaceutical composition including compounds described herein, methods of imaging, method of forming a compound as described herein, and the like. In particular, embodime
...

Purine Nucleoside Monophosphate Prodrugs for Treatment of Cancer and Viral Infections

The present invention is directed to compounds, compositions and methods for treating or preventing cancer and viral infections, in particular, HIV, HCV, Norovirus, Saporo virus, HSV-I, HSV-2, Dengue virus, Yellow fever, and HBV in human patients or other animal hosts. The compounds are certain 6-su
...

Internet-based Cognitive Diagnostics Using Visual Paired Comparison Task

Disclosed are methods for diagnosing declarative memory loss using mouse tracking to follow the visual gaze of a subject taking a visual paired comparison test. Also disclosed are methods for diagnosing dementia such as mild cognitive impairment and Alzheimer's disease.
...

Catecholamine Derivatives for Obesity and Neurological Disorders

Novel compounds, compositions, and methods related to the activation of the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of a compound containing a catecholamine backbone and pharmaceutically acceptable salts, prodrugs, and deri
...

Polyoxometalate Water Oxidation Catalysts and Methods of Use Thereof

Homogeneous water oxidation catalysts (WOCs) for the oxidation of water to produce hydrogen ions and oxygen, and methods of making and using thereof are described herein. In a preferred embodiment, the WOC is a polyoxometalate WOC which is hydrolytically stable, oxidatively stable, and thermally sta
...

Potent Combinations of Zidovudine and Drugs That Select for the K65R Mutation in the Hiv Polymerase.

Combinations of antiretroviral nucleoside reverse transcriptase inhibitors, and methods for their use in treating retroviral infections, are provided. In one embodiment, the combinations include non-thymidine nucleoside antiretroviral agents, such as tenofovir-DF, abacavir, APD and DAPD, that select
...

Methods and Systems for Screening for and Diagnosing Dna Methylation Associated with Autism Spectrum Disorders

Methods and systems for population screening and diagnostics are provided. In particular methods and systems for population screening of individuals for genetic disorders due to alterations in DNA methylation and for the diagnostic testing for such disorders are provided.
...

Nanocarrier Therapy for Treating Invasive Tumors

Liposomes of a size of less than 200 nanometers target tumors and preferentially deliver imipramine blue to tumors, including brain tumors such as gliomas. The imipramine blue decreases the invasiveness of the tumors, and inhibits tumor metastasis. The liposomes include cholesterol and chemically pu
...

Methods and Devices for Drug Delivery to Ocular Tissue Using Microneedle

Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprach
...

Methods of Identifying Safe NMDA Receptor Antagonists.

Processes are providedfor the identifcation a compound that is useful to treat or prevent a disorder that lowers the pH in a region of affected tissue comprising assessing the difference in potency, or potency boost, of the compound at physiological pH versus disorder-induced pH in a cell that expre
...

Use of Rankl to Induce Differentiation of Microfold Cells (M Cells)

The differentiation of microfold (M) cells is important in mucosal immunity. The differentiation of M cells is desirable, such as in situations in which a host response to an antigen is sub-optimal, or wherein increased uptake of a compound is desired. Methods are provided herein for increasing a mu
...

Alzheimer's Disease Imaging Agents

This invention provides compounds and methods of imaging amyloid deposits using radiolabeled compounds. This invention also provides a method of inhibiting the aggregation of amyloid proteins to form amyloid plaques or deposits, a method of determining a therapeutic compound's ability to inhibit agg
...

Methods and Compositions for Improved Delivery of Therapeutic and Diagnostic Agents

Among other things, this disclosure provides for compounds having a targeting moiety linked to a therapeutic moiety and/or a diagnostic moiety; the synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and, methods for treating or diagnosing disorders. Som
...

Imaging Agents

This invention provides amino acid derivatives useful in detecting and evaluating brain and body tumors, including (1S,2S) anti-2-[18F]FACPC and (1R,2R) anti-2-[18F]FACPC.
...

Targeting Therapeutic Agents

Provided are devices, systems, and methods for targeted administration of therapeutic agents to a subject. For example, provided are devices, systems, and methods for targeting the administration of peri-urethral bulking agents.
...

Branched Multifunctional Nanoparticle Conjugates and their Use

Disclosed herein are compounds and compositions including a polyglycerol nanocarrier, a therapeutic agent or imaging agent, and optionally a targeting agent. In certain aspects the disclosed compounds include biocompatible hyperbranched polymer nanocarriers. Such compounds and compositions are usefu
...

PH-dependent NMDA receptor antagonists

NMDA receptor blockers, including pH-sensitive NMDA receptor blockers, are provided as neurprotective drugs that are useful in stroke, traumatic brain injury, epilepsy, and other neurologic events that involve acidification of brain or spinal cord tissue. Compositions and methods of this invention a
...

Heterocyclic Peptide Ketoamides

A novel class of peptide a-ketoamides useful for selectively inhibiting calpains, selectively inhibiting cysteine proteases, and generally inhibiting all cysteine proteases, having the formula M-AA2-AA1-CO-NH-(CH2)n-R3. Processes for the synthesis of peptidyl a-ketoamide derivatives. Compositions an
...

Re-engineered UV Damage Endonuclease, Compositions and Methods

Provided are methods and compositions for reducing damage to skin by ultraviolet light and other agents that cause distortion to double stranded DNA and methods for reducing damage to other organs due to such DNA distortion. These compositions comprise a novel truncated UV damage endonuclease (a tru
...

BHC80 - Histone Complexes and Uses Thereof

Provided herein is the tertiary structure of domains of the BHC80 protein, including the PHD finger domain, such as when the BHC80 protein is complexed with an unmodified histone H3 tail in the presence of zinc. The invention provides structural and functional information for use in the identificati
...

Cyanine-containing Compounds for Cancer Imaging and Treatment

This invention relates generally to cyanine-containing compounds; pharmaceutical compositions comprising cyanine-containing compounds; and methods of using cyanine-containing compounds for cancer cell imaging, cancer cell growth inhibition, and detecting cancer cells, for example. Compounds of the i
...

Methods for Determination of Protein Phosphatase Activity, and Uses in Predicting Therapeutic Outcomes

One aspect of the present disclosure encompasses methods for determining a protein kinase or phosphatase activity in a biological sample, comprising: contacting in a reaction mix a first test sample and a fluorescently-labeled peptide substrate capable of being modified by a protein phosphatase or a
...

PREPARATION OF SYNTHETIC NUCLEOSIDES VIA p-ALLYL TRANSITION METAL COMPLEX FORMATION

This invention provides highly regioselective and stereoselective processes for preparing synthetic nucleosides. A process for the preparation of synthetic nucleosides is provided that comprises a) preparing a bicycloamide derivative, b) reacting the bicycloamide derivative with a nucleic acid base
...

Methods of Making Monoclonal Antibodies Using Fusion-Peptide Epitope Adoptive Transfer (F-PEAT) Technology

Disclosed are compositions and methods for related to monoclonal antibodies specific for single amino acid variation in an antigen.
...

Evaluating Magnetic Resonance Spectra

Provided are methods, systems and computer program products evaluating magnetic resonance (MR) signals from a sample. The methods and systems can be used to evaluate MR signals from various constituents (e.g., metabolites, macromolecules) of the sample.
...

Modulation of Sodium Channels By Nicotinamide Adenine Dinucleotide

The present invention relates to the use of oxidized nicotinamide adenine dinucleotide (NAD+) or of its reduced form, NADH, as sodium channel modulators. The present invention also relates to the use of compositions containing NAD+ or NADH to treat conditions associated with sodium channel current,
...

Systems and Methods for Preventing Mistransfusion

In some embodiments, a system and a method for preventing mistransfusion of a patient pertain to obtaining a sample of the patient's blood, obtaining a sample of blood that is about to be infused into the patient, mixing the samples together, determining whether the samples are compatible, and if th
...

Compositions and methods for generating an immune response

We have developed DNA and viral vectors that can be used, alone or in combination, as a vaccine against one HIV clade, subtype, or recombinant form of HIV or against multiple HIV clades, subtypes, or recombinant forms. Moreover, the vectors can encode a variety of antigens, which may be obtained fro
...

Immunogenic Compositions and Methods of Use Thereof

Embodiments of the disclosure encompass compositions and methods for generating immune responses in an animal or human host Embodiments of the compositions encompass proteins derived from the surface proteins of bacteria and protozoa, and in particular the flagellum component flagellin, and which ha
...

Branched Diepoxide Compounds for the Treatment of Inflammatory Disorders

The present invention provides certain diepoxide carbocyclic compounds wherein at least one carbocyclic ring carbon includes two non-epoxide substituents, and pharmaceutical compositions containing the same, for the treatment or prophylaxis of inflammatory, autoimmune and hyper- or abnormally prolif
...

2'-fluoronucleosides

The 2'-fluoronucleoside is provided to treat hepatitis type B, hepatitis type C, HIV(human immunodeficiency virus), and abnormal cell proliferation including tumor and cancer. The pharmaceutical composition for treating hepatitis type B in human comprises the 2'-fluoro-beta-D-nucleoside represented
...

Predictive and Diagnostic Methods for Cancer

The present disclosure encompasses methods of diagnosing the presence of a cancer, and particularly a cancer of prostate or breast tissue, in a human subject, predicting the outcome or severity of the disease and methods of reversing the prostate cell transformation based on the presence or absence
...

Vascular Access to Extra-vascular Space

Provided are methods for accessing tissue in the vicinity of a blood vessel. Also provided are devices for use in a lumen of a patient's organ and methods for shunting interior volumes of organs.
...

Coated Quantum Dots and Methods of Making and Using Thereof

The present disclosure provides embodiments of a new class of hydroxylated quantum dots. The quantum dots have a hydroxylated coat disposed thereon, and which serves to minimize non-specific cellular binding and to maintain the small size of quantum dot probes. Embodiments of the coated quantum dots
...

Steroid Analogues for Neuroprotection

Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the
...

Reduced Dye Probes for the Detection of Radical Oxygen Species

Reduced dyes, such as hydrocyanines, deuterocyanines, and/or other deuterated dyes, such as deuteraled leuco dyes, capable of detecting one or more reactive oxygen species are described herein The reduced dyes are generally prepared by reducing the oxidized dye with a reducing agent, such as sodium
...

Non-myelosuppressive Compounds, Pharmaceutical Compositions Thereof, and Methods of Treatment

The present invention provides microtubule targeting compounds that are myelo-sparing. Particularly, the MTCs of the invention are structurally designed to exhibit specificity for inhibiting ss-tubulin isotypes that are not related to the myelosuppression associated with other known MTCs. The invent
...

Nucleoside Derivatives for Treatment of Caliciviridae Infections, Including Norovirus Infections

A method and composition for treating a host infected with a Caliciviridae virus, such as a Norovirus, comprising administering an effective treatment amount of a described modified nucleoside or a pharmaceutically acceptable salt thereof, is provided.
...

Image-based Control Systems

Image-based control systems and methods automate the adjustment of medical devices. An image based-control system for an endoscope can include, in addition to the endoscope, a processing system and an actuator. The processing system can receive an image from an image capture device of the endoscope.
...

Compositions and Methods for the Treatment of Infections and Tumors.

PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD- 1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subje
...

Modified Factor VIII

Methods of treating patients with Factor VIII deficiency by administration of modified porcine factor VIII are disclosed. The particular modified porcine factor VIII is one in which most of the B domain has been removed through genetic engineering. This modified factor VIII is particularly useful fo
...

Methods of Administering Porcine B-domainless FVIII

The present invention provides a method of administering porcine B-domainless factor VIII (OBI-1) to a patient having factor VIII deficiency to provide more rapid and effective protection against bleeding episodes, compared to formerly available methods, or to provide more effective protection to su
...

Methods and Compositions for the Display of Polypeptides on the Pili of Gram-positive Bacteria

Provided herein are methods and compositions for the display of polypeptides of interest on the tip of pili of Gram-positive bacteria. According to the present invention, the polypeptide of interest is amino terminal to a Gram-positive bacterial pilus tip protein or an active variant or fragment the
...

Haptics and Virtual Reality

Licensing of Software and/or Hardware technologies covering high performance collocated virtual reality and haptics, applicable to a number of fields.
...

Upper Arm Wearable Exoskeleton

An exoskeleton having a first cuff adapted to be coupled to a user's lower limb is disclosed. The exoskeleton also includes a second cuff adapted to be coupled to the user's upper limb and a third cuff adapted to be coupled to the user's body. A first motor is mounted on the third cuff and has a fir
...

Apparatus and Method for Preform Relaxation and Flow Control in Liquid Composite Molding Processes

A vacuum-induced injection molding apparatus is disclosed. The apparatus includes a tool surface having an injection port extending therethrough. A flexible film extends over and is sealingly coupled to the tool surface. The flexible film comprises an outer surface and an inner surface such that the
...

Macromolecular Diffusion and Release from Self-assembled B-hairpin Peptide Hydrogels

A hydrogel for delayed release of an anionic macromolecule, wherein the hydrogel comprises the anionic macromolecule, 150 mM NaCl, and a peptide selected from the group consisting of SEQ ID NO:1 through SEQ ID NO:33 in an aqueous medium at a pH of 7.4; wherein the anionic macromolecule has an isoele
...

Snap-off Blade Knife with Safety Stop

A snap-off blade knife having a handle including a proximal portion, a distal portion, and a handle axis extending between the proximal portion and the distal portion is disclosed. The knife also includes a blade slidingly disposed within the handle along the handle axis. The blade comprises a plura
...

Multijunction High Efficiency Photovoltaic Device and Methods of Making the Same

Photovoltaic devices and methods of making photovoltaic devices are provided. The photovoltaic device comprises a plurality of solar cells electrically coupled to each other. The plurality of solar cells are formed of respective semiconductor material having different band gaps. Each solar cell incl
...

Method for Maximum Power Point Tracking of Photovoltaic Cells By Power Converters and Power Combiners

This invention relates to a method for Maximum Power Point Tracking (MPPT) a photovoltaic cell by a power converter that provides an output current at voltages useful to operate electronics or charge batteries. This invention also relates to a method for Maximum Power Point Tracking (MPPT) multiple
...

Systems and Methods for Obtaining an Image Alpha Matte

Methods and systems for obtaining an alpha matte for an image are disclosed. First and second known portions of an image are determined. The alpha matte for the image is estimated based on an initial fuzzy connectedness (FC) determination between the entire image and the first and second known porti
...

Perlecan Fragments as Biomarkers of Bone Stromal Lysis

A method for the detection in a body fluid of perlecan polypeptide fragments that are biomarkers of tumor metastasis, and antibodies for detecting these fragments are described. An immunoassay kit for detecting the presence of these biomarkers in a body fluid, such as serum or urine, is also describ
...

Nozzle-Based, Vapor-Phase, Plume Delivery Structure for Use in Production of Thin-Film Deposition Layer

A physical vapor deposition effusion method comprising translating a strip material through a physical vapor deposition zone in a deposition chamber and providing first and second substantially closed vessels located serially along the processing path in the same deposition chamber, each vessel emit
...

Pan-Antagonists for the Androgen Receptor and Androgen Receptor Mutants Associated with Anti-Androgen Withdrawal

Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.
...

High Lift Mower for Plastic Mulch

A high-lift mower is disclosed. The mower includes a frame, at least two wheels disposed along opposite sides of the frame and having a space between them, and a blade rotation mechanism, mounted to the frame, for providing a rotational force relative to the frame. A blade assembly is coupled to the
...

Delivery System for Heparin-Binding Growth Factors

A device comprising a scaffold coated with a protein having at least 83% identity to the amino acid sequence of the core protein of domain I of a mammalian perlecan, wherein at least one glycosaminoglycan is attached to the protein is described. The device may be used in vitro or in vivo to induce r
...

Fertility Enhancement Using Lipid Carriers and Bioactive Molecules

The invention relates to a composition and method for enhancing fertilization. Fertilization enhancement is achieved by effectively delivering bioactive molecules with a lipid anchor (GPI-linked proteins) to the surface of epididymal or ejaculated sperm. The process may be facilitated or promoted in
...

Biosynthesis of Metalloid Containing Nanoparticles By Aerobic Microbes

Isolated tellurite-resistant or selenite-resistant marine organisms capable of precipitating tellurium or selenium when grown aerobically are described. A method for using these isolated organisms to produce an aqueous suspension of purified nanoparticles comprising tellurium or selenium and the nan
...

Delivery of Hydrogels As Sprays

A method for delivering beta-sheet peptide hydrogels to a target surface by shear-thinning and spraying the peptide hydrogel on the surface is provided. The beta-sheet peptide hydrogels can be applied over a range of thicknesses and can cover broad surface areas. The beta-sheet peptide hydrogels may
...

Emulsification of Concentrated Dispersions of Colloidal and Nanoparticles

A process to coat a shear thickening fluid onto a material which comprises emulsifying dispersions of a shear thickening fluid (STF) dissolved in a miscible carrier fluid or a partially miscible carrier fluid to form an emulsion and applying said emulsion to the material. The invention also relates
...

Ballistic Resistant Fabric Armor

A woven ballistic resistant fabric armor system comprising at least one ply having a yarn-yarn angle between the warp and fill yarns of less than 90 DEG , with each ply oriented relative to an axis along the thickness of the plies such that adjacent plies have a different yarn-yarn angle, a differen
...

Identification of Fat and Lean Phenotypes in Chickens Using Molecular Markers

The present invention provides methods of screening chickens to determine those more likely to have a lean or fat phenotype. The invention also provides methods of screening chickens to identify a polymorphism associated with a fat or lean phenotype.
...

Method of Making Stable, Homogeneous Potassium Hydride Dispersions

A stable, homogeneous dispersion of potassium hydride is formed by reacting a mixture of wax and potassium metal with hydrogen.
...

Systems and Methods for Identifying Structurally Or Functionally Significant Amino Acid Sequences

Methods and computer readable storage mediums for identifying structurally or functionally significant amino acid sequences encoded by a genome are disclosed. At least one structurally or functionally significant amino acid sequence encoded by a genome may be identified by compiling an observed freq
...

Rubbery-block Containing Polymers, Fiber Sizings Thereof and Composites Thereof

The present invention relates generally to sizing compositions for fibers used in composite materials. More specifically, this invention relates to siloxane fiber sizing solutions comprising rubbery-polymers and their use in preparing composite materials. Using the sizings of the present invention n
...

Injectable Beta-hairpin Peptide Hydrogel That Kills Methicillin-resistant Staphylococcus Aureus

A peptide comprising the sequence VKVKVRVKVDPPTKVKVRVKV-NH2 forms a hydrogel which has the ability to shear-thin and recover. The hydrogel, both before and after shear-thinning, is capable of killing bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).
...

Fibers, Tubes and Porous Structures of Metal and Metal Oxide

Nanoscale materials comprised of metal or metal oxide which are in the form of fibers or tubes or which have a porous structure can be prepared using composite fibers containing admixtures of polymers and metal precursors and/or metal oxide precursors.
...

Single-wall Carbon Nanotube Supercapacitor

A supercapacitor comprising a cathode, an anode, a first single-walled carbon nanotube (SWNT) film electrode adjacent the cathode, a second SWNT film electrode adjacent the anode, and separator disposed between the first and second electrodes. The SWNT film electrodes may be manufactured by a non-fi
...

System and Method for Modulator-based Optical Interconnections

Systems and methods for modulator-based optical interconnections are disclosed. An optical interconnect system comprises a substrate, a wave path, a coupling structure, and a modulator. The wave path may be a waveguide disposed on the substrate. The coupling structure is coupled to the substrate and
...

Electromagnetic Detection Apparatus and Methods

Systems and methods for detecting electromagnetic waves are disclosed. A system for detecting such waves includes a device having a first magnetic layer having a fixed magnetization direction, a second magnetic layer having an unfixed magnetization direction responsive to the electromagnetic wave, a
...

Method and Apparatus for Measuring Microrelief of an Object

An apparatus for determining microrelief of an object periphery, comprising a ring for attachment to the object, a carriage adapted to traverse the ring; a non-contact measurement system mounted on the carriage; an advancement mechanism for incrementally advancing the carriage to a plurality of loca
...

Dynamic Vibrational Method and Device for Vocal Fold Tissue Growth

Dynamic vibrational methods and devices for inducing differentiation of stem cells into vocal fold fibroblast-like cells or for generating vocal fold-like tissue from cultured cells. Also provided are matrices providing sustained release of growth factors, and bioreactors generating and delivering a
...

Terahertz Emitter with High Power and Temperature Operation

Terahertz emitting devices are disclosed. The terahertz emitting device comprises a wafer and a current source. The wafer includes silicon carbide and a dopant. In particular, the wafer may consist of 6H silicon carbide; a nitrogen dopant having a concentration of approximately 1018 cm-3; a boron do
...

Processes for Fabricating All-back-contact Heterojunction Photovoltaic Cells

Processes for fabricating back contacts for photovoltaic cell devices are disclosed. The processes involve depositing a passivation layer on the back surface of a wafer, depositing an emitter layer on the passivation layer, depositing a metal layer on the emitter layer, laser firing selected areas o
...

Method of Solution Preparation of Polyolefin Class Polymers for Electrospinning Processing Included

A process to make a polyolefin fiber which has the following steps: mixing at least one polyolefin into a solution at room temperature or a slightly elevated temperature to form a polymer solution and electrospinning at room temperature said polymer solution to form a fiber.
...

Formation of Reflective Surfaces in Printed Circuit Board Waveguides

The present invention relates to an apparatus and method for creating an printed circuit board including one or more waveguides having one or more reflective surfaces. Waveguides are embedded within a printed circuit board. A reflective surface is formed within the embedded waveguides by mechanicall
...

Computer Controlled Flow Manipulation for Vacuum Infusion Processes

Methods and apparatus for vacuum infusing resin into a fabric preform within a mold. The methods comprise deploying a VIPR chamber to increase permeability in a desired location identified by predictive modeling as best to achieve a desired flow front geometry. Suitable apparatus comprise a VIPR cha
...

Novel Hydrogels and Uses Thereof

The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution.
...

Process and System for Manufacturing a Customized Orthosis

A process and system for fitting, customizing and manufacturing an orthosis for a subject. 3-dimensional coordinates for a plurality of landmarks corresponding to anatomical characteristics of the subject, means for attachment of the orthosis to the subject, and a reference plane are digitally acqui
...

Compositions and Methods for Repair of Tissues

Biomaterials providing sustained release of growth factor for repair of tissues such as bone and cartilage are disclosed. The biomaterials comprise a proteoglycan derived from domain I of perlecan and a growth factor, and, optionally, collagen.
...

Ferromagnetic Resonance and Memory Effect in Magnetic Composite Materials

Magnetic devices incorporating magnetic composite materials are disclosed. A tunable magnetic device includes magnetic composite material and a magnetic field source. The magnetic composite material includes an insulator and magnetic material embedded in the insulator. The magnetic material has a re
...

Molecular Markers for Identification of Fat and Lean Phenotypes in Chickens

The invention provides molecular methods of screening chickens to determine those more likely to have a lean or fat phenotype by identifying the presence of at least one polymorphism in genetic material of a chicken in the thyroid hormone repressible gene (THRG) or its 3' untranslated region (SEQ ID
...

Shear thickening fluid containtment in polymer composites

Shear thickening fluid suspoemulsions are shown to exhibit unique material properties that have potential application in a broad range of fields of use. Suspoemulsions containing shear thickening fluids as immiscible blends exhibit a nontrivial shear thickening response for volume fractions as low a
...

Eo Polymer-based Dual Slot Waveguide Modulators

Electro-optic modulators are disclosed. An electro-optic modulator comprises an electro-optic polymer layer, semiconductor layers, ferroelectric material layers, and electrodes. The semiconductor layers are positioned on each surface of the electro-optic polymer layer. The refractive index of the se
...

Method and system for detecting damage in aligned carbon nanotube fiber composites using networks

Methods and structural defect detectors for detecting a structural defect in composites are presented. An exemplary method includes forming a nanocomposite including a plurality of nanotubes mechanically aligned in a principal direction within a polymer matrix. A voltage is applied to the nanocompos
...

Scanning Optical Microscope with Long Working Distance Objective

A scanning optical microscope, including: a light source to generate a beam of probe light; collimation optics to substantially collimate the probe beam; a probe-result beamsplitter; a long working-distance, infinity-corrected objective; scanning means to scan a beam spot of the focused probe beam o
...

Power Converter and Power Combiner for Power-limited Power Sources

This invention relates to a hysteretic input-regulating high-output impedance power converter for converting the energy output of power-limited power sources such as solar cells to provide output current at voltages useful to operate electronics or charge batteries. This invention also relates to a
...

Tetrazine-based Bio-orthogonal Coupling Reagents and Methods

Coupling reactions, suitable for use in organic or aqueous media, are performed by contacting a 1,2,4,5-tetrazine with a dienophile. The dienophile may be covalently bonded to a protein, and the coupling reaction may be performed in biological media such as those containing cells or cell lysates. Th
...

Isolation of quiescin-sulfhydryl oxidase from milk

Methods for isolating a highly purified QSOX enzyme from milk or whey are described. The enzyme may be used to generate intermolecular and intramolecular disulfide bridges and to facilitate oxidative protein folding.
...

Method of Fabricating Monolithic Nanoscale Probes

A monolithic pair of nanoscale probes, including: a substrate having a cavity that extends from a surface of the substrate into its body; a dielectric layer formed on the substrate; a pair of nanoscale probe precursors formed over the dielectric layer; a plurality of sub-monolayers of electrode mate
...

High Efficiency Hybrid Solar Cell

This invention relates to a high efficiency hybrid solar cell comprised of a dichroic mirror, a first cell stack comprising two cells, the first cell being a GaInP cell and the second cell being a GaAs cell and a second cell stack comprising three cells, the first cell being a Si cell, the second ce
...

I-III-VI2 Photovoltaic Absorber Layers

The invention provides a film having a composition AgWCu1-WInrGaxKySe2(I-Z)Q2Z; wherein K is Al or Tl or a combination of these; Q is S or Te or a combination of these; w is in a range from 0.01 to 0.75; x is in a range from 0.1 to 0.8; and r, y and z are each independently in a range from 0 to 1, p
...

Intelligent Powered Mobility for Infants and Special Needs Children

A powered mobility device for advancing cognitive, perceptual and motor abilities of a child lacking natural mobility is disclosed. The device includes a seat sized for the child to be secured therein and a motorized drive assembly coupled to the seat. A local operating instrument is operably couple
...

Thermal Evaporation Sources for Wide-area Deposition

A thermal evaporation source includes: a crucible configured to contain a volume of evaporant and a vapor space above the evaporant; a manifold body having within it a hollow expansion chamber that is flowably connected to the vapor space via one or more restriction orifices; one or more effusion no
...

Anti-whiplash Vehicle System with Active Head Restraint

An active head restraint system includes a fluid driver assembly coupled to a vehicle seat assembly. The fluid driver assembly is actuatable in response to a predetermined movement of the vehicle seat assembly. A fluid driven assembly is in fluid communication with the fluid driver assembly. The flu
...

Photovoltaic Cell

A photovoltaic cell has two electrodes and a hole injection layer. A liquid crystal material and a plurality of particles can be disposed between the electrodes.
...

Method for Switching Magnetic Random Access Memory Elements and Magnetic Element Structures

A method for storing data in a magnetic memory element of an array of elements which avoids inadvertent switching of other elements is disclosed. First and second magnetic fields are applied to a selected magnetic element for a first time interval to switch the element into an intermediate state whe
...

Preparation of Cobalt-boron Alloy Catalysts Useful for Generating Hydrogen from Borohydrides

A method of making a cobalt-boron alloy includes contacting an aqueous suspension of an oxide of cobalt, particularly a highly crystalline cobalt oxide, with a borohydride such as sodium borohydride. The resulting alloy may be used as a catalyst to produce gaseous hydrogen by hydrolysis of aqueous s
...

Page: 1  -  <10  -  98  99  100  101  102  103  104  -  10>  -  117   Next»