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Prenylated Bisphosphonates As Anti-tuberculosis Agents
The invention provides methods to treat a mycobacterium infection and methods to inhibit mycobacterial polyprenyl pyrophosphate synthesis with a compound of formula I. The invention also provides novel compounds of formula I as well as salts and prodrugs thereof.
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Agr-mediated Inhibition of Methicillin Resistant Staphylococcus Aureus
The present invention involves the use of activators of bacterial Agrquoroum-sensing systems to prevent or reverse biofilm formation in methicillin resistant Staphylococcus aureus (MRSA), or to restore sensitivity of MRSA bio films to antibiotics.
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Schweinfurthins and Uses Thereof
Disclosed is a method for preventing or treating an undesirable condition in a subject carrying cells homozygous null for the neurofibromatosis type 1 gene or subjects that are haploinsufficient for the neurofibromatosis type 1 gene, the method comprising administering to a subject in need thereof a
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Compositions and Methods for Detecting Predisposition to a Substance Use Disorder
The present invention provides screening kits, compositions, and diagnostic methods for determining whether a subject has a predisposition to, or likelihood of having, a substance use disorder by determining a nucleic acid methylation profile from a biological sample from the subject, wherein a give
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Diagnosis of Abdominal Aortic Aneurysm Using Biomarkers
The invention relates to proteins associated with abdominal aortic aneurysm (AAA). These proteins, which are present in blood, are expressed in individuals with AAA at either elevated or reduced levels compared to healthy individuals. The invention provides methods for diagnosing AAA. The invention
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RCA Locus Analysis to Assess Susceptibility to AMD and MPGNII
The invention relates to gene polymorphisms and genetic profiles associated with an elevated or a reduced risk of alternative complement cascade deregulation disease such as AMD and/or MPGNII. The invention provides methods and reagents for determination of risk, diagnosis and treatment of such dise
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Pparatus and Semiconductor Co-crystal
The invention provides a method to enforce face-to-face stacking of organic semiconductors in the solid state that employs semiconductor co-crystal formers (SCCFs), to align semiconductor building blocks (SBBs). Single-crystal X-ray analysis reveals [pi]-orbital overlap optimal for organic semicondu
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Human Protein Acyl Transferases and Methods of Uses Therefor
The present invention provides the identification of human Ras palmitoyl acyl transfersase complexes, and nucleic acids coding therefor. In addition, methods of screening for modulators of human Ras palmitoyl acyl transfersase, including high throughput yeast screens, are also provided.
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Variant TLR4 Nucleic Acid and Uses Thereof
The invention provides methods to identify polymorphisms at the human TLR4 locus, as well as methods to identify individuals at risk of indications that increase their morbidity and mortality.
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Dental Brush Assembly and Method for Making the Same
A dental brush assembly includes an elongate handle having first and second coupling ends sized and shaped to couple with at least a first detachable dental brush. The first coupling end is at a first angle relative to a handle longitudinal axis and the second coupling end is at a second different a
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Immunostimulatory Nucleic Acids
The invention relates to immunostimulatory nucleic acid compositions and methods of using the compositions. The T-rich nucleic acids contain poly T sequences and/or have greater than 25% T nucleotide residues. The TG nucleic acids have TG dinucleotides. The C-rich nucleic acids have at least one pol
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Fiberscopes and Fiber Bundles
An elongate imaging fiber bundle may include a plurality of elongate optical fibers coherently arranged in the bundle, the plurality including peripheral fibers at a periphery of the bundle and deep fibers deep to the peripheral fibers, and a coating surrounding the plurality of fibers. An exposed l
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Semiconductor Heterostructure Nanowire Devices
Nanowire devices comprising core-shell or segmented nanowires are provided. In these nanowire devices, strain can be used as a tool to form metallic portions in nanowires made from compound semiconductor materials, and/or to create nanowires in which embedded quantum dots experience negative hydrost
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Direct Oxidation of Calcium/Calmodulin Dependent Protein Kinase II and Associated Diagnostic and Therapeutic Methods
Calcium/calmodulin dependent protein kinase II (CaMKII) has been found to be directly oxidized, and direct oxidation of CaMKII was observed to result in calcium independent activation of CaMKII. Antibodies that bind specifically to oxidized forms of CaMKII (oxCaMKII) were generated and were utilized
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Diagnosis of Age-related Macular Degeneration Using Biomarkers
The invention relates to proteins associated with age-related macular degeneration (AMD). These proteins, which are present in blood, are expressed in individuals with AMD at either elevated or reduced levels compared to healthy individuals. The invention provides methods for diagnosing AMD. The inv
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Zinc Finger Nuclease for the CFTR Gene and Methods of Use Thereof
The present invention provides new zinc finger proteins and zinc finger nuclease (ZFNs) that find particular using in repairing the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
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Bioactive Sutures for the Treatment of Cancer
The present invention relates to compositions and method for the treatment of cancer using a suture or dressing providing a plurality of tumor cell antigens and/or an immunostimulatory agent to a subject in need of such treatment.
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IMMUNOGENIC COMPOSITIONS FOR ACTIVATING ?d T CELLS
Disclosed are compositions, kits, and methods for activating, expanding, or stimulating ?d T cells that include recombinant attenuated microbes. The compositions may include pharmaceutical compositions that are used as ?d T cell stimulating vaccines or immunogenic compositions for preventing or trea
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Method for Multi-scale Meshing of Branching Biological Structures
A structural and functional model for a lung or similar organ is virtually defined by encoding aspects of branching passageways. Larger passageways that are visible in medical images are surface mesh fitted to the anatomical surface geometry. Smaller distal passageways, beyond a given number of bran
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Methods and Compositions for Treating Brain Diseases
The present disclosure provides targeting peptides and vectors containing a sequence that encodes targeting peptides that deliver agents to the brain.
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Use of Rpa4 and RPA4/RPA32 Hybrid Polypeptides for Modulating Cell Proliferation
Disclosed are polynucleotides and polypeptides that are useful for modulating cell proliferation. The polynucleotides may comprise coding regions for RP A4 and RPA4/RPA32 hybrid polypeptides. The polynucleotides may be used in gene vectors for inhibiting cell proliferation in a patient in need there
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Hypervirulent Mutant of Agrobacterium Tumefaciens
This disclosure relates to a mutant Agrobacterium tumefaciens that is functionally deleted for the atu1060 gene that codes for the cyclic di-GMP synthase Atu1060, as well as methods for its use in transforming plants with desired transgenes. Such bacteria are more virulent than currently used strain
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Self-assembled Toroidal-spiral Particles and Manufacture and Uses Thereof
Toroidal-spiral shaped particles, their method of manufacture, and uses thereof are disclosed. The toroidal-spiral particles can contain at least one active agent, such as a drug, and provide a controlled, sustained release of the active agent.
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Nicotinic Acetylcholine Receptor Ligands and the Uses Thereof
The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an anim
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Apparatus for Biomedical Imaging
A system that incorporates teachings of the present disclosure may include, for example, a method involving capturing spectral interference from an optical coherence tomography imaging probe comprising a micro-electro-mechanical system (MEMS) scanning mirror, and a partial reflector for supplying im
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Identification and Use of Peptide Inhibitors of Protein Synthesis
The present invention discloses compositions of peptide inhibitors of protein synthesis, and methods of identifying peptide inhibitors that are capable of inhibiting protein synthesis through an interaction at a stem-loop H18 in 16S rRNA of a 30S ribosomal subunit. Screening methods for peptides are
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Method for modulating or controlling sodium channel current by reactive oxygen species (ROS) originating from mitochondria
Method for modulating or controlling sodium channel current of a cell includes inducing mitochondrial reactive oxygen species (ROS) production in the cell.
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Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
Solutions and suspensions comprising polymerized hemoglobin derived from human blood are disclosed. The solutions and suspensions may comprise cell culture medium, an enzyme (such as a protease), and/or a buffer. Processes of preparing the solutions and suspensions are also disclosed. The solutions
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Materials and Methods for Making Improved Micelle Compositions
Provided are methods of treatment of many different diseases and disorders using micelle and sterically stabilized crystalline compounds of the invention.
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High affinity TCR proteins and methods
T cell receptors (TCRs) that have higher affinity for ligand than wild type TCRs are provided. These high affinity TCRs are formed by mutagenizing a T cell receptor protein coding sequence to generate a variegated population of mutants of the T cell receptor protein coding sequence; transforming the
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Pak1 Agonists and Methods of Use
The present invention is directed to Pak1 agonists and methods of use.
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Soybean Gene for Resistance to Aphis glycines
An Aphis glycines resistance Rag2 gene is provided herein, along with methods for identifying its presence using marker-assisted selection. A cultivar of G. max having resistance to Aphis glycines conferred by the Rag2 gene has been identified. The Rag2 gene, as well as the methods, aphid-resistant
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Compositions and Methods for Inhibiting Entry of a Hepatic Virus
The present invention embraces Niemann-Pick C1-like 1 protein antagonists and agents that inhibit hepatic virus infection for use in the prevention and treatment of a hepatic virus infection.
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Nanoconjugates and Nanoconjugate Formulations
The invention provides a drug-polymer nanoconjugate that includes a drug covalently bonded to a polymer. The nanoconjugate can include a block copolymer coating and/or an albumin coating. The drug of the drug-polymer nanoconjugate can be one or more of a variety of therapeutic agents linked to the p
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Fitness assay and associated methods
The present invention provides an assay for determining the biochemical fitness of a biochemical species in a mutant replicating biological entity relative to its predecessor. The present invention further provides a continuous fluorogenic assay for measuring the anti-HIV protease activity of protea
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Antimicrobial Therapy for Bacterial Infections
The disclosure provides compounds and methods to treat bacterial pathogenesis, and demonstrates that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.
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Synergistic Antibiotic Combinations and Derivatives
Improved antibiotic analogs, and synergistic combinations of antibiotics designed based on structural crystallographic analysis, are provided as well as pharmaceutical compositions comprising the improved analogs and the synergistic combinations, and methods for their production and use. The synergi
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Arabinitol Dehydrogenases from Neurospora crassa
Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an arabinose containing substrate. Recombinant and heterologously expressed arabinitol dehydrogenases are use
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Light emitting and lasing semiconductor devices and methods
A two terminal semiconductor device for producing light emission in response to electrical signals, includes: a terminal-less semiconductor base region disposed between a semiconductor emitter region and a semiconductor collector region having a tunnel junction adjacent the base region; the base reg
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Variable Electric Field Strength Metal and Metal Oxide Microplasma Lamps and Fabrication
Preferred embodiments of the invention provide microcavity plasma lamps having a plurality of metal and metal oxide layers defining a plurality of arrays of microcavities and encapsulated thin metal electrodes. Packaging encloses the plurality of metal and metal oxide layers in plasma medium. The me
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Semiconducting Microcavity and Microchannel Plasma Devices
Preferred embodiments of the invention provide semiconducting microcavity plasma devices. Preferred embodiments of the invention are microcavity plasma devices having at least two pn junctions, separated by a microcavity or microchannel and powered by alternate half-cycles of a time-varying voltage
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Gas Purification System and Method for Liquefaction of Dilute Gas Components
The invention provides gas purification methods and systems for the recovery and liquefaction of low boiling point organic and inorganic gases, such as methane, propane, CO2, NH3, and chlorofluorocarbons. Many such gases are in the effluent gas of industrial processes and the invention can increase
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System for Executing 3D Propagation for Depth Image-based Rendering
A system is disclosed for executing depth image-based rendering of a 3D image by a computer having a processor and that is coupled with one or more color cameras and at least one depth camera. The color cameras and the depth camera are positionable at different arbitrary locations relative to a scen
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Regulation of Apoptosis By Neural Specific Splice Variants of IG20
Pro-apoptotic signaling caused by down-modulation of KIAA0358 or expression of IG20-SV4 effectively induces spontaneous apoptosis and sensitization to TNFa-induced apoptosis in neuroblastoma cells. Methods and composition to enhance cell death in neuroblastoma are provided. Methods and compositions
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Nonequilibrium Chemovoltaic Fuel Cell
A chemovoltaic cell converts chemical energy generated by an in-situ molecular hydrogen oxidation reaction into electrical energy by creating a chemically induced nonequilibrium electron population on a catalytic surface of a Schottky structure, followed by charge separation and electric power gener
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Colorimetric Sensor Arrays Based on Nanoporous Pigments
A colorimetric array includes a substrate, a first spot on the substrate, and a second spot on the substrate. The first spot includes a first nanoporous pigment that includes a first nanoporous material and a first immobilized, chemoresponsive colorant. The second spot includes a second nanoporous p
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Systems for Applying a Thermal Barrier Coating to a Superalloy Substrate
Systems for applying a thermal barrier coating to a superalloy substrate including at least one target for supplying a materia) for making ihe thermal barrier coating; at least one laser operably directed toward the target for liberating atomic particles from the target: and a plasma torch for gener
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Hybrid Plasma-semiconductor Optoelectronic Devices and Transistors
The invention provides combination semiconductor and plasma devices, including transistors and phototransistors. A preferred embodiment hybrid plasma semiconductor device has active solid state semiconductor regions; and a plasma generated in proximity to the active solid state semiconductor regions
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Fluorescence detection enhancement using photonic crystal extraction
Enhancement of fluorescence emission from fluorophores bound to a sample and present on the surface of two-dimensional photonic crystals is described. The enhancement of fluorescence is achieved by the combination of high intensity near-fields and strong coherent scattering effects, attributed to le
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Selective Aliphatic C-H Oxidation
A composition including a complex of a metal, a tetradentate ligand, at least one ancillary ligand, and a counterion may be used for selective sp3 C-H bond oxidation. The tetradentate ligand may include a N-heterocyclic-N,N'-bis(pyridyl)-ethane-1,2-diamine group or a N,N'-bis(heterocyclic)-N,N'-bis(
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Directed Assembly of Three-dimensional Structures with Micron-scale Features
Polyelectrolyte inks comprising a solvent, a cationic polyelectrolyte dissolved in the solvent, and an anionic polyelectrolyte dissolved in the solvent, are described. The concentration of at least one of the polyelectrolytes in the solvent is in a semidilute regime.
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Optical frequency up-conversion of femtosecond pulses into targeted single bands in the visible and ultraviolet
An apparatus and methods for generating a substantially supercontinuum-free widely-tunable multimilliwatt source of radiation characterized by a narrowband line profile. The apparatus and methods employ nonlinear optical mechanisms in a nonlinear photonic crystal fiber (PCF) by detuning the waveleng
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Temperature-Dependent Nanoscale Contact Potential Measurement Technique and Device
The present invention provides a microcantilever capable of independently measuring and/or controlling the electrical potential and/or temperature of a surface with nanometer scale position resolution. The present invention also provides methods of manipulating, imaging, and/or mapping a surface or
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Mechanical Nanoresonator for Extremely Broadband Resonance
In an embodiment, provided are nanoresonators, nanoresonator components and related methods using the nanoresonators to measure parameters of interest. In an aspect, provided is a nanoresonator component comprising an elongated nanostructure having a central portion, a first end, and a second end an
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Hydrothermal Processing (HTP) of Algae Grown in HTP Waste Streams
A process for the conversion of organic waste to biofuel is provided comprising cultivating organisms in the aqueous product of the HTP conversion process.
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Method of Forming an Array of High Aspect Ratio Semiconductor Nanostructures
A new method for forming an array of high aspect ratio semiconductor nanostructures entails positioning a surface of a stamp comprising a solid electrolyte in opposition to a conductive film disposed on a semiconductor substrate. The surface of the stamp includes a pattern of relief features in cont
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Microcavity Plasma Devices with Non-uniform Cross-section Microcavities
An embodiment of the invention is an array of microcavity plasma devices having microcavities of non-uniform cross-section. The array includes a first electrode that is a thin metal foil or film including a plurality of non-uniform cross-section microcavities therein that are encapsulated in oxide.
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Method and System Having Adjustable Analog-To-Digital Conversion Levels
An adaptive Analog to Digital Converter (ADC) that adjusts the representation levels used in the conversion process so as to optimize system performance. By establishing system performance criteria by which to select or adjust the signal value range associated with each digital representation and/or
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Highly Permeable Polymer Membranes
Provided are substantially flat membranes that include a block or graft co-polymer and a water transport protein, such as Aquaporin-Z, or a synthetic mimic of such proteins. Also provided are methods of removing contaminants from a liquid, by contacting the liquid with a substantially flat membrane
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System for Cyber Investigation and Data Management
A system for executing a cyber investigation by a non-expert user, including a computer having a processor, a memory, and a display; a computer-readable medium having stored thereon instructions for execution of a wizard application, the processor adapted to execute the instructions when the compute
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Methods for Producing Fertile Crosses between Wild and Domestic Soybean Species
Methods for producing hybrids between domestic and wild soybean that are fertile and can be further bred with other soybean plants are provided, thus allowing transfer of desirable traits and genes from the wild soybean into the domestic soybean. This invention also provides novel media for producin
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Hdac Inhibitors and Therapeutic Methods Using the Same
Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, traumatic brain injury, stroke, malaria, an aut
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Methods for Diagnosing Endometriosis
Provided herein is a method for diagnosing and monitoring endometriosis in a subject by measuring levels of the [beta]-subunit of fibrinogen.
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Method and Composition for Potentiating an Opiate Analgesic
Composition and methods of treating pain and reducing or reversing tolerance to opiate analgesics are disclosed. The composition and method utilize an opiate analgesic and an endothelin antagonist as active agents to treat pain in mammals, including humans.
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Compositions and Methods for the Treatment of Krabbe and Other Neurodegenerative Diseases
Provided are compositions and methods for the treatment of Krabbe and other neurodegenerative diseases, including storage diseases such as GMl gangliosidosis, Niemann-Pick disease, Tay-Sachs disease, Sandhoff disease, metachromatic leukodystrophy, Canavan disease, Pelizaeus-Merzbacher disease, and s
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Activated Mesenchymal Stem Cells for the Prevention and Repair of Inflammatory States
Inflammatory cytokines e.g. IFN-? serve as initiating stimuli for MSC immunosuppresive activity in vivo. Other inflammatory cytokines, such as TNF alpha, the molecule hemoxygenase I, and TLR ligation of MSC may also provide such a response.
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Methods of Inhibiting Tumor Cell Proliferation
The invention provides methods for inhibiting tumor cell proliferation by inhibiting FoxM1B activity, expression, or nuclear localization in a tumor cell. The invention also provides methods for preventing tumor progression in an animal comprising inhibiting FoxM1B activity, expression, or nuclear l
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Methods of Treating Diastolic Dysfunction and Related Conditions
The invention provides a method of treating diastolic dysfunction, e.g., diastolic dysfunction with preserved ejection fraction, in a subject. The method comprises administering to the subject in an amount effective to treat the diastolic dysfunction a cardiac metabolic modifier comprising a structu
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COMPOSITIONS AND METHODS FOR INHIBITING Ga PROTEIN SIGNALING
The present invention comprises compositions and methods for specifically inhibiting signaling through Ga13, Gai and Gaq subunits.
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Compositions and Methods for Treating Neurodegenerating Diseases
This invention provides agents, compositions, pharmaceutical compositions and methods for treating or slowing the progression of a neurodegenerating disease, such as Alzheimer's disease and a demyelinating disease.
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Modulation of MLCK-L Expression and Uses Thereof
In various aspects and embodiments the invention provides methods and reagents for controlling gene expression, and for treating disorders and diseases. Embodiments provide methods and reagents specifically for the regulation of MLCK expression and for the use thereof in treating disorders and disea
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Method of Regulating Cell Growth Using a Proteasome Inhibitor
This invention provides methods and pharmaceutical compositions for regulating cell growth or inducing apoptosis in a cell, particularly a mammalian tumor cell. Specifically, the invention provides methods for inducing apoptosis in a tumor cell comprising contacting the tumor cell with a proteasome
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Apparatus for Managing a Neurological Disorder
A system that incorporates teachings of the present disclosure may include, for example, a Neuro Sensing and Stimulation Device having a conductive lead for implanting in a brain of a living entity, a sensor coupled to the conductive lead for collecting data associated with one or more electrical si
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Use of polypeptides of cupredoxin family in cancertherapy.
Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death or uncontrolled growth. The pres
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Portable Active Fluid Powered Ankle-foot Orthosis
A portable active pneumatically-powered ankle foot orthosis. A lower leg mount and a foot bed are pivotally coupled at or proximate to an ankle position. A pneumatically powered rotary actuator is configured to receive power from a wearable fluid power source and provide controlled force and resista
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Non-invasive Optical Imaging for Measuring Pulse and Arterial Elasticity in the Brain
An optical imaging system and a method for generating a report regarding elasticity of arteries in the brain of a subject under test. Light output from the light source of the imaging system non-invasively illuminates at least one blood vessel or region of interest in the brain and, upon the interac
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Compositions and Methods for Quantitatively Monitoring Lipids
Provided herein are fluorescent lipid binding proteins (FLBPs). The FLBPs comprise a lipid binding domain linked to a fluorophore, whereby the fluorophore's fluorescence emission undergoes a spectral change upon lipid binding.
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Methods of Diagnosing Diastolic Dysfunction
Diagnostic methods relating to a cardiac ventricular dysfunction are provided. In some embodiments, the diagnostic method is a method of diagnosing diastolic dysfunction in the absence of systolic dysfunction in a subject. The method comprises assaying a sample obtained from the subject for evidence
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Enzyme Inhibiting Compounds and Methods
The invention provides compounds, compositions, and methods for studying the Rohmer pathway and for treating bacterial infections or parasitic infections. The parasitic infection can be a protozoan infection, such as malaria. The compounds and compositions can also be used as antibiotics, for exampl
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Human Single-chain T Cell Receptors
A soluble human single-chain T cell receptor (TCR) having the structure: Va2-L-Vss or Vss-L-Va2, wherein L is a linker peptide that links Vss with Va, Vss is a TCR variable ss region, and Va2 is a TCR variable a region of the family 2 is provided. The provided scTCR is useful for many purposes, incl
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Device for Determining Vertebral Distances of the Spinal Column of a Patient
The invention relates to devices for determining vertebral distances of the spinal column of a patient. The devices are characterized in particular in that vertebral distances of the patient while walking in a building or outdoors can be easily detected. For this purpose, at least two marks are appl
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X-ray Marker for Visually Comparing and for Controlling the Image Processing in Digital X-ray Recordings, in Particular for a Thorax X-ray Recording for a Patient Lying Down
The invention relates to an X-ray marker (1) that is also to be X-rayed in an X-ray recording of an organ of a patient (3) to be examined. The X-ray marker (1) has such a geometric X-ray weakening structure, so that the associated X-ray image (R) approximately shows the expected X-ray image structur
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Method for Detecting the Existence of Renal Calculi And/or Inflammation of the Excretory Urinary Tracts
The invention relates to methods for detecting diseases of the excretory urinary tracts. The aim of the invention is to provide a method for detecting the existence of diseases of the excretory urinary tracts, which can be carried out non-invasively, thus allowing first indications of disease, e.g.
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Spect Gamma Camera, Spect Scanner, and Uses of a Spect Gamma Camera
The invention relates to a SPECT gamma camera (10) comprising a scintillator (1) to convert incoming gamma quanta (?) having radiation energy especially in the 100 keV to 250 keV range into secondary quanta of light (h v ), a focusing device (2) mounted upstream of the scintillator to focus the inco
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Method of Determining Sensitivity of Human Or Non-human Animal Cells to an IAP Antagonist
cFLIP serves as a biomarker for efficacy of treatment with IAP antagonists, including Smac peptidomimetics.
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Method and Apparatus for Calibrating a Digital X-ray Radiation Detector
The invention relates to a method and to an apparatus (1) for calibrating a digital X-ray radiation detector (4, 14), which is irradiated with X-rays for creating at least one calibrating image, wherein the calibrating image is linked to an X-ray image recorded with the digital X-ray radiation detec
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Safety Binding for a Snowboard
The invention relates to a safety binding (1) for a snowboard, particularly a safety binding to be attached in pairs to a snowboard. The invention solves the problem of reducing force peaks on the lower extremities of the athlete, which, for example, in the event of a fall exceed a force value which
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Marking Clip for an Area of the Inside Wall of the Stomach Or Intestine
The invention relates to marking clips for an area of the inside wall of the stomach or intestine. These are characterized in particular by the fact that damaged or treated areas of the inside wall of the stomach or intestine can be easily identified and in this way can be easily found again. For th
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Connector with a configuration aid on its outer shell or an insulative body disposed in the outer shell
An electronic connector comprises an outer shell having a first side and a second side, an insulative seat body having a first side and a second side, a plurality of terminals extending along the first side of the insulative seat body, and a configuration aid formed on the outer shell. The insulativ
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Construction diagram and construction of KOLEV MOTORS internal combustion engine
Engine layout
With the innovative layout KOLEV MOTORS internal combustion engines provide for:
• Reduced overall dimensions of constructions;
• Reduced specific mass рег power unit;
• Reduced friction losses and increased mechanical efficiency;
• Reduces production and operational costs;
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Method for the Synthesis of A-ring Aromatized Acetyl Minocyclines
The invention relates to a process for production of A-ring aromatized acetyl-minocycline.The object of the invention, a resource-light process for the production of A-ring aromatized acetyl-Minocycline Formula $ F1 where R to R = acetyl and / or H to provide, it is also feasible on an industrial
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Method for Detecting the Existence of Renal Calculi And/or Inflammation of the Excretory Urinary Tracts
The invention relates to methods for detecting diseases of the excretory urinary tracts. The aim of the invention is to provide a method for detecting the existence of diseases of the excretory urinary tracts, which can be carried out non-invasively, thus allowing first indications of disease, e.g.
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Method for the Synthesis of A-ring Aromatized Acetyl Minocyclines
The invention relates to a method for the production of A-ring aromatized acetyl minocyclines. The aim of the invention to provide a less complex method for the production of A-ring aromatized acetyl minocyclines of the formula (I), wherein R1 to R5 = acetyl and/or H, which can also be used on an in
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An Apparatus and a Method for Automatic Treatment Adjustment After Nervous System Dysfunction
The present invention relates to an apparatus for automatic adjustment of a treatment of a target person to be treated based on calculated recovery prediction data for predicting a change of a sensory function of said target person in response to said treatment.
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Two/three-dimensional multi-layer circuit carrier producing method for e.g. automobile industry, involves applying layer of strip conductor and dielectric layer on topmost dielectric layer alternative
The method involves applying a dielectric layer (4) i.e. thermoplastic polymer layer, on certain regions of a set of electrical strip conductors (2) and the surface of a two/three-dimensional basebody (1) by injection moulding. Another set of electrical strip conductors (6) is applied on the surface
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Electrically operated valve used as a pilot valve for controlling gas and liquid streams comprises media connections arranged in a housing close to a front or side surface of a control head
Electrically operated valve comprises media connections (4) arranged in a housing close to a front or side surface of a control head (1). A radial or axial gap of a constant width is formed between the control head and the media connections. The discharge direction of the media connections is orient
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Stroboscope Light for Subwoofers and Low Frequency Speakers
This is a brand new invention illuminating subwoofer speaker and allowing the spectator to see the rhythm and customizable speaker movement! The device is used to illuminate the subwoofer in an (car) audio system. By analyzing audio signal it enhances the visual rhythm of the speaker and could be us
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Light Emitting Semiconductor Methods and Devices
A method for producing light emission from a two terminal semiconductor device with improved efficiency, includes the following steps: providing a layered semiconductor structure including a semiconductor drain region comprising at least one drain layer, a semiconductor base region disposed on the d
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Solvent Removal and Recovery from Inorganic and Organic Solutions
A process for recovering solvents from inorganic and organic solutions is disclosed. The process utilizes a polymer capable of selectively extracting the solvent from the inorganic or organic solution. Introduction of the polymer into the solvent solution creates formation of a polymer-rich phase an
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Light Emitting and Lasing Transistor Devices and Methods
A method for producing light emission from a semiconductor device includes the following steps: providing a semiconductor base region disposed between a semiconductor emitter region and a semiconductor collector region that forms a tunnel junction adjacent the base region; providing, in the base reg
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