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Obtaining recyclable material from tailings ponds receiving low-valuable industrial sludge, comprises rinsing the sludge in a tailing, where rinsing regime influences the sludge so that the material s
The method for obtaining recyclable material from tailings ponds receiving low-valuable industrial sludge, comprises rinsing the sludge in a tailing, where the rinsing regime influences the sludge so that the recyclable material contained in the sludge sediments in an area (8) of the tailings in ord
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Method for technological sedimentation of low valuable sludge on rising surface of residual stockpile, comprises concentrating the sludge through a controllable rinsing regime in a determined area of
The method for technological sedimentation of low valuable sludge (S) on rising surface (A) of residual stockpile, comprises concentrating the sludge through a controllable rinsing regime in a determined area of the sedimentation of the sludge stream on the rinsing surface at mineral-containing recy
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Pressed Carbonaceous Or Carbon-bonded Fireproof Aluminum Oxide Products, and Method for Producing Same
The invention relates to pressed carbonaceous or carbon-bonded fireproof aluminum oxide products, and to a method for producing same. The fireproof products according to the invention are used, for example, as unitary plugs, immersion castings, and cauldron distribution pipes used for casting metals
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Lubricants for hot glass processes and use of the lubricant to the surface finishing of glass
The invention relates to a lubricant for hot glass processes, in particular in the form of lubrication processes in the hollow glass industry, but also in the role lubrication in the flat glass industry, in the lubrication of flat glass molds, also in use as a plate cooler, where the tube glass manu
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Process for electrolytic deposition of copper
The invention can be in copper refining electrolysis, which operate for a uniform deposition with cathodic additives in the electrolyte, will be applied. The invention is based on the technical task of finding for the electrolytic refining of copper additions, which ensure smooth even at higher curr
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Method and Apparatus for Sorting Particles
Methods and an apparatuses are provided for sorting particles according to the shape thereof in at least two classification stages in a chronological or spatial sequence.
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Method for the Production of Porous, Silicon-based Materials, Composite Ceramic-ceramic and Ceramic-metal Materials Derived Therefrom, and Uses Thereof
The invention relates to a method for producing porous materials from silicon-based polymers or silicon-based inorganic solid materials by forming addition compounds from hydridochlorosilanes and pyridine or pyridine derivatives, followed by pyrolysis.
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Method and Device for the Selective Classification of Particles According to the Size Thereof
The invention relates to a method and to a device for the selective classification of particles according to the size thereof, determined by a maximum main dimension (a, b, c) of the particle geometry, by conducting the classification by means of passages (3) in a screening structure (3, 4, 5, 11) t
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Lubricant for surface refinement of glass for mold lubricating processes in the hollow glass industry, comprises aluminum salt of fatty acids and/or carbon-based solvents and/or suspensions, which con
The lubricant for surface refinement of glass for mold lubricating processes in the hollow glass industry and also for roller lubrication in flat glass industry for the lubrication of flat glass press molds, for the tube glass production using lubricated mandrels or for the lubrication of rollers du
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Implantable System for Determining Accommodation Need
The invention relates to an implantable system for determining accommodation need in an artificial accommodation system by means of measuring eyeball orientation comprising a) at least one optical system (3), b) at least one information recording system (8) having means for recording the eyeball ori
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Microarray-based Spatial Filter
The invention relates to a spatial filter measuring arrangement (1) and a spatial filter measuring device (2) comprising at least one sensor (4, 5; 41I - 41IV; 51) and a spatial filter, wherein electromagnetic radiation, in particular light, that is emitted or reflected by a measurement object (13),
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Suture Anchor System
The invention relates to a suture anchor system for fixing sutures to bone, having a screw, an adjacent anchor, a cannulation in the anchor, and a thread, wherein the anchor comprises two opposite indentations at which the cannulation terminates at each end. In order to provide a suture anchor syste
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Device and Method for Measuring Tibial Translation
The invention relates to a device and a method for measuring tibial translation in mammals under loading. The device has at least a first and a second splint, which can be fastened laterally to the upper and lower leg and have an overlapping region in the area of the knee joint. The displacement of
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Medical Implant for Treating Arthritis in Joints of the Human Or Animal Body
The invention relates to a medical implant for treating arthritis in joints of the human or animal body, in particular in the knee joint of a patient. In order to prevent extensive means for inserting stable plates in the gap of the knee joint, the invention provides two magnet bodies (9, 10; 20) th
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Medical implant i.e. flexible hollow implant, for ventilation of middle ear in head of human, has flexible peristalsis elements assigned to implant and causing pressure balance between openings on imp
The implant i.e. flexible hollow implant (5), has peristalsis elements flexible over entire length and assigned to the flexible hollow implant and causing pressure balance between distal and proximal openings on the flexible hollow implant by peristalsis movements. The peristalsis elements are desig
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Device for testing endurance limit of medical device, has two fixing devices at end cross sections of medical device, and two actuators which are coupled with fixing devices
The device (1) has two fixing devices (3,4) at the end cross sections of a medical device, and two actuators which are coupled with the fixing devices. The device has a guiding element (10) at which the medical device is formed or shaped. A deformation kinematic of the medical device is recreated at
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Method and Device for Cell Sample Diagnosis
The invention relates to a method for cell sample diagnosis on a cell sample or cell culture. In addition, the invention relates to a computer program product, a data storage medium with a computer program product stored or written thereon according to the invention, and a device for cell sample dia
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Bioequivalence Dialysis
The present invention relates to a method for treating blood composition disorders and blood function disorders. Said method comprises steps, in which blood or blood plasma of a patient is brought into extracorporeal contact with a second fluid (bioequivalent), wherein said second fluid is blood or
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Method for Determining the Clamping Force on a Mechanical Joint Connection Connecting At Least Two Components
The invention relates to a method for determining the clamping force on a mechanical joint connection connecting at least two components by coupling sound waves into the joint connection. The invention is characterized by the combination of the following method steps: exciting the mechanical joint c
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Biodegradable Copolymer Comprising Amylopectin Or Glycogen Suitable for Delivering Nucleic Acid Materials Into Cells
The invention is related to a biodegradable copolymer, which is suitable for delivering nucleic acid materials into cells, and which comprises a amylopectin or glycogen and at least one cationic polymer or cationic monomer having amino functions, which is bound to the amylopectin or glycogen by este
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Device for in Situ Milling of Joint Surfaces
The invention relates to a device for in situ milling of joint surfaces, comprising a milling device (20 24) and a joint clamping device (10). The invention further relates to a use of a corresponding device and to a method for in situ milling of joint surfaces. The joint clamp device (10) of the de
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Device for ventilating the middle ear, has stent having hollow cylinder which has funnel-shaped expansion at two ends, where inner diameter of hollow cylinder lies in certain range
The device has a stent (10) having a hollow cylinder (12) which has a funnel-shaped expansion (18) at two ends (14,16). The inner diameter of the hollow cylinder lies in the range of 0.5 millimeter to 10 millimeter. The stent has a length in the range of 1 centimeter to 5 centimeter along the longit
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Repositioning Device for the Handling of Distal Radius Fractures By Means of a T-shaped Osteosynthesis Plate
The invention relates to a repositioning device for the handling of distal radius fractures by means of a T-shaped osteosynthesis plate, comprising a long leg and a short leg, disposed in a T-shaped and angular manner in relation to said long leg, wherein the short, distal leg has a face that comes
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Device and Method for Detecting Falls
The present invention relates to a device and method for detecting falls. The problem of the present invention is to specify a device for detecting falls that ensures the reliable detection of falls at the earliest possible time, wherein the device according to the invention should be designed as co
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Radial Plain Bearing with Optional Hydrostatic And/or Hydrodynamic Function
The invention relates to a radial plain bearing that comprises a shaft (1), a bearing shell (2) having a cylindrical sliding surface (15) in each case, several lubrication pockets (3) distributed over the circumference, to a device for hydrostatically supplying lubricant, and to a device for hydrody
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Insufflator
The invention relates to an insufflator comprising a supply connection (22) and a delivery connection (14) and a pressure and flow measuring unit located between said connections (14, 22) for determining a gas pressure that prevails in the delivery connection and a measuring variable that characteri
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Method for speech recognition in patients with neurological disorder or laryngectomy for e.g. vocal rehabilitation, involves acoustically reproducing output signal and/or converting signal into writte
The method involves receiving noise, which is generated in an oral cavity (6) of patients, during articulation of speech of the patients. An input signal is subjected in a digital form in a signal processing device for detecting linguistic patterns. The detected patterns are converted to an output s
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Root pin for endodontic complex supply, has fibers with longer longitudinal rigidity and smaller longitudinal rigidity arranged in center of root pin and boundary region of root pin respectively
The pin (100) has a base body made of a fiber-reinforced plastic matrix (13) incorporated on two kinds of fibers (14, 15). The two kinds of fibers have different wetting behaviors and/or different mechanical characteristics, and are radially arranged at two-part short-fiber reinforcements. The fiber
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Hull Structure, in Particular for Seagoing Vessels
The shell structure has a primary support structure (14) in form of a grid of interconnected cross members (17), and longitudinal members (18) for carrying a wall (16). A secondary reinforcing system (19) made from parallel profiled braces (20) is fastened to the wall. A sheet covering (22) is fitte
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Magnetically Mounted Artificial Joint
The invention relates to a prosthesis for replacing a joint compound in the same magnetic fields of joint head 10, socket 12 and pivot collar 14 can be superimposed so that the repulsive forces produce a state of suspension of the joint head 10 in the bearing and the damping effect is maximal.The in
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Combination for an Adhesive Bonding of Biological Tissues
The present invention relates to a combination, especially for bonding and / or fixation of biological tissues, the combination of components a) a polysaccharide stickstofffunktionalisiertes and b) a terminally functionalized Oligolacton covers.
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Method and Device for Controlling Robots for Welding Workpieces
The invention relates to a method for controlling robots for welding three-dimensional workpieces, comprising the following steps: positioning and tacking profiles to a plate in order to form the workpiece to be welded, depicting the workpiece by means of a three-dimensional imaging system in the fo
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Method and Arrangement for Electrically Contacting an Object Surrounded By a Membrane, Using an Electrode
The invention relates in particular to a method for electrically contacting a membrane-object (30) with an electrode (10, 100).According to the invention is provided that is used for contacting at least one electrode (100) with a conductive carrier (110), on which a plurality of nano-needles (120) i
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Combination of an antibody and a bacterium, which expresses Fc-receptors or proteins, which bind the light chain of an antibody, useful for the treatment of tumors and their precursors, preferably col
Combination of at least one antibody and a bacterium, which expresses Fc-receptors or proteins, which bind the light chain of an antibody, is claimed, where at least one antibody is bound via its Fc-region to an Fc-receptor of the bacterium or via its light chain to protein of the bacterium, which b
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Predefined image pattern forming method for photosensitive layer attached on e.g. offset printing plate, involves allowing part of radiation to lie outside incompletely hardenable pixel and within com
The method involves exposing a part of an incompletely hardenable pixel (21) using an amount of energy below a hardening-threshold value (Eth). A radiation is produced on a photosensitive layer (19) attached on a carrier substrate such that maximum energy density of a radiation, which is irradiated
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Bite guard splint i.e. lower jaw bite guard splint, for keeping open of respiratory tract at asleep of patient, has fastening elements provided for connection element to piercing-like implant at regio
The splint (13) has fastening elements (14) e.g. hooks (15), for a connection element (17) e.g. fastening lug, to a piercing-like implant at a region of a tongue body of a patient. The fastening elements are arranged at the lower jaw bite guard splint, and are provided at interior sides of the lower
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Endodontic pin for introducing into a curved root canal with a single-piece base body, comprises a plastic matrix, which is reinforced with fibers that are embedded parallel to a longitudinal axis in
The endodontic pin for introducing into a curved root canal with a single-piece base body (1), comprises a plastic matrix (2), which is reinforced with fibers (3) that are embedded parallel to a longitudinal axis in the plastic matrix. The base body has zones with different flexural and torsional st
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Method for manufacturing root pin for endodontic pin-stump-provision for use in fine grinding device, involves forming elongate semi finished product from glass, ceramics, whisker by fine grinding in
The method involves forming an elongate semi finished product (10) from glass, ceramics, whisker or carbon fiber reinforced polymer by fine grinding in a hollow grinding device. The semi finished product is moved in the hollow grinding device by rotating a tool. A dipping bath is sealed in a low vis
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Bioequivalence Dialysis
The present invention relates to a method for treating blood disorders and blood disorders compensation. This includes steps in which one blood or blood plasma of a patient outside the body brings with a second liquid (bioequivalent) in contact with the second liquid blood or blood is modified, whic
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Use of Plant Extracts Comprising Polyphenol for Treating Adiposity and Diabetes Mellitus Type 2
The present invention relates to the use of plant extracts comprising polyphenol for treating adiposity and diabetes mellitus type 2. The extracts comprise specific polyphenol compounds, in particular procyanidin A3 isomers. The invention further relates to methods for producing extracts of said kin
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Method and Device for Measuring the Concentration of Substances in Gaseous Or Fluid Media Through Optical Spectroscopy Using Broadband Light Sources
The invention relates to a method and to a device for using partially non-stabilized broadband light sources to accurately measure partially broadband-absorbing substances using referencing measuring cells. In order to create a low-cost, high-resolution, and at the same time fast spectrographic devi
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Implant and Bone Screw Having Interlocking Cams
The invention relates to a fixation device for bones, consisting of an implant (1; 11), having at least one through hole (2; 12), to be fastened to the bone, and of at least one bone screw (3; 13) to be fastened in said through hole (2; 12), fastening elements (5; 15) being arranged in the through h
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Method and Arrangement for Detecting a Fall of a Person
An arrangement for detecting a fall of a person (1) has an air pressure sensor (in device 4) and an evaluating device (in device 4 or 8). If the measurement value of the air pressure sensor (11) meets a predefined criterion, a fall of the person (1) is detected.
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Stabilization of Cells By Ionic Liquids
The present invention relates to the use of ionic liquids and/or compatible solutes for storing and stabilizing eukaryotic cells, above all blood cells such as leukocytes, platelets, or erythrocytes. The invention further relates to compositions which comprise eukaryotic cells and ionic liquids and/
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Implantable System for Restoring Accommodation Capacity Using Internal Energy
An implantable system for restoring accommodation capacity includes at least one ring configured to be implanted in a ciliary sulcus and a capacitor with a first capacitor plate and a second capacitor plate. The first capacitor plate is arranged on an implantable ring and the second capacitor plate
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Device for Osteosynthesis
The aim of the invention is to provide an osteosynthesis plate (100) or a kit for osteosynthesis that clearly reduces the risks associated with the treatment of a bone fracture using the osteosynthesis of a bone plate, in particular the danger of infections and pressure necrosis compared to those of
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Root Pin for the Endodontic Care of a Root-stump
In order to improve a root pin (10) for the endodontic care of a root-stump, in particular combined with occlusal caps, said root pin has a one-piece base body (14) made from a plastic matrix material and it offers increased safety in relation to pin and root fractures. According to the invention, s
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Active Wound Healing Film for Eardrum Perforations
The invention relates to a film for closing a perforation of the eardrum, which comprises a positioning element, which is disposed in the outer ear channel, and a closure element, which consists of a flexible material, which can be resorbed, wherein said closure element is implemented as a spiral at
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Hull Structure, in Particular for Seagoing Vessels
The invention relates to a hull structure, in particular for seagoing vessels, comprising a primary bearing structure (14) that is in the form of a grating consisting of transverse bearings (17; 34) and longitudinal bearings (18; 35) that are connected together for supporting at least one wall (16),
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Implants with membrane diffusion controlled active ingredient release
Implant having a structure for implantation in a human or animal body, comprises implant base body, primer layer applied at least partially to the surface of the implant, active ingredient layer consisting of one or more active ingredients applied to at least a portion of the surface of the primer l
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Method for electrochemical treatment of electrode for electrochemical measurements, involves heating electrode, and applying negative or positive potential to electrode
The method involves heating an electrode (1), and applying a negative or a positive potential to the electrode. A potential of less than minus 1 volt or more than 1.5 volt, particularly less than minus 2 volt or more than 2.5 volt is applied to the electrode. A saturated calomel electrode is applied
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Method for Determining Centers of Mass for Large Structures
The invention relates to a method and a hoisting device for determining centers of mass and mass for large structures. According to the method, a hoisting device is used which has at least two different suspension devices, wherein the suspension devices each comprise a cable element and a suspension
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Hip joint orthosis for e.g. supporting musculature of patient after hip joint implantation, has electro stimulation device for generating electro stimulation, where beginning and ending of stimulation
The orthosis has a hip belt including three parts in the form of shell elements (1), which are movably arranged and fixed on a flexible anti-rotation cable. An orthosis joint (5) includes an adjustable, progressive resistance, which works against movement of a patient at an extreme position. An elec
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Method and Device for Controlling Robots for Welding Workpieces
The invention relates to a method for control of robots for welding of three-dimensional workpieces comprising: positioning and stapling profiles (3) on a plate (2) the formation of the welded workpiece (1), Mapping the workpiece by means of a three-dimensional imaging system into form of three-dime
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Implantable System for Determining the Accommodation Requirement By Measuring the Eyeball Orientation Using an External Magnetic Field
The present invention relates to an implantable system for determining the Akkommodationsbedarfs in an artificial accommodation system by measuring the Augapfelorientierung using an external magnetic field, comprising a) at least one optical system (3), b) at least one to the ciliary non-contact inf
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METHODS AND COMPOSITIONS FOR IDENTIFYING INHIBITORS OF MUTS-alpha OR MUTS-beta INTERACTION WITH MUTL-alpha
Disclosed are methods and kits for screening potential inhibitors of MutS[beta] by screening agents for the ability to selectively inhibit interaction between MutS[beta] and MutL[alpha]. Also disclosed are kits for performing the methods of the invention.
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Up and Down Conversion Systems for Production of Emitted Light from Various Energy Sources
A system for energy upconversion and/or down conversion and a system for producing a photostimulated reaction in a medium. These systems include 1) a nanoparticle configured, upon exposure to a first wavelength ?1 of radiation, to generate a second wavelength ?2 of radiation having a higher energy t
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Combination Therapy in the Treatment of Cancer
Disclosed herein is a method of treating a tumor by administering to the subject a treatment effective amount of a therapeutic antibody and an alkylating agent.
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Delivery Method
The present invention relates, in general, to RNA silencing and, in particular, to a method of effecting targeted delivery of an RNA silencing moiety using a targeting moiety that binds to a cell surface receptor and mediates internalization of the RNA silencing moiety to be accessible to Dicer. Als
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Affinity Displacement Molecular Separation
Provided herein are methods for identifying molecules that compete with a ligand for binding to a protein. The method comprises contacting a ligand with a proteome to allow protein members of the proteome to bind with the ligand, followed by the removal of the unbound ligand. At least one test molec
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Monoclonal Antibody Production in B Cells and Uses Therof
The presently disclosed subject matter provides methods of inhibiting a host innate response to activator-mediated proliferative signals in a primary B cell. In some embodiments a method is provided for immortalized primary B cells. In some embodiments a method is provided for increasing efficiency
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Droplet-Based Surface Modification and Washing
The present invention relates to droplet-based surface modification and washing. According to one embodiment, a method of splitting a droplet is provided, the method including providing a droplet microactuator including a droplet including one or more beads and immobilizing at least one of the one o
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Methods of Inhibiting Cancer Cell Growth with Hdac Inhibitors and Methods of Screening for HDAC10 Inhibitors
Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibitor, and methylpyruvate is also
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Peripheral Reticular Pigmentary Change and Age-Related Macular Degeneration
Examination of 956 age-related macular degeneration cases showed that the complement factor H variant (Y402H, C allele at rs1061170) increases risk for the development of peripheral reticular pigmentary change. AMD phenotypes of 796 carriers of the CFH Y402H variant were compared to the AMD phenotyp
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Methods and Compositions for Treating Disorders Caused By a Deficiency in a Gene Product of a CLN Gene
The present invention provides methods and compositions for treating a disorder associated with a deficiency in a gene product of a CLN gene in a subject (e.g., neuronal ceroid lipofuscinosis (NCL)), comprising administering to the subject an effective amount of a sphingolipid (e.g., galactosylceram
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Cross-species Chimeric RNA Molecules
Methods to reduce the expression of at least one gene of an intracellular pathogen in a host cell are provided, wherein the method comprises introducing into a host cell a heterologous polynucleotide comprising or encoding a miRNA that fuses with at least one mRNA of the pathogen and reduces the tra
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Manassantin Compounds and Methods of Making and Using Same
Provided are manassantin compounds and methods of using the compounds. Provided are methods of treating a disease, the method comprising administering a compound according to Formula I. Further provided are pharmaceutical compositions comprising compounds according to Formula I. Also provided are me
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Predicting Cancer Risk and Treatment Success
Provided herein are methods for predicting the likelihood of recurrence of a cancer using gene expression profiles. Methods for developing treatment plans for individuals with cancer are also provided. Kits including gene chips and instructions for predicting recurrence of a cancer and computer read
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Prevention of Flap Necrosis in Plastic Surgery
PROBLEM TO BE SOLVED: To provide a method for resolving or preventing vasoconstriction and preventing depletion of blood flow or restoring blood flow in a pedicle flap or any other microsurgery. ; SOLUTION: The method for preventing necrosis in a pedicle flap or in any microvascular surgery comprise
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Sour Taste Receptor Compositions and Methods
The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory pr
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Methods, Systems and Computer Program Products for Characterizing Structures Based on Interferometric Phase Data
Structure profiles from optical interferometric data can be identified by obtaining a plurality of broadband interferometric optical profiles of a structure as a function of structure depth in an axial direction. Each of the plurality of interferometric optical profiles include a reference signal pr
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Methods of Subclassification of Ductal Carcinoma of the Breast
Provided herein are methods of determining the aggressiveness or indolence of a ductal carcinoma in situ lesion. Also provided are methods of developing treatment plans for subjects with a ductal carcinoma in situ lesion based on the aggressiveness of the lesion.
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Modulation of immune response by non-peptide binding stress response polypeptides
A recombinant stress response polypeptide that lacks an antigen binding domain, and methods for using the recombinant stress response polypeptide to elicit an immune response, for example an anti-tumor response, in a subject.
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Method for Distinguishing Follicular Thyroid Adenoma (FTA) from Follicular Thyroid Carcinoma (FTC)
Follicular thyroid adenoma (FTA) is distinguished from follicular thyroid carcinoma (FTC) by comparing amount of an expression product of at least one gene selected from the group consisting of DDIT3, ARG2, ITM1, C1orf24, TARSH, and ACO1 in a test follicular thyroid specimen to a normal control thyr
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Multiscale Optical System
A means of enabling an imaging lens system that overcomes some of the costs and disadvantages of the prior art is disclosed. A lens system in accordance with the present invention reduces or eliminates one or more aberrations of an optical input by separating image collection functionality from imag
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Substituted Porphyrins
Discloses are compounds according to Formula I. Further provided are methods of reducing oxidative stress in a cell, methods of treating a disease including cancer, and methods of treating a subject with a disorder associated with oxidative stress, the methods including administering a compound acco
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Methods for single-pass volumetric bidirectional blood flow imaging Spectral Domain Optical Coherence Tomography using a modified hilbert transform
The present subject matter relates to in vivo volumetric bidirectional blood flow imaging using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting
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Asymmetric Alpha Functionalization and Alpha, Alpha Bisfunctionalization of Aldehydes and Ketones
The present invention relates, generally, to asymmetric a-functionalization and to asymmetric a,a-bisfunctionalization of ketones and aldehydes and, in particular, to chiral auxiliaries suitable for use in effecting such functionalizations and to methods of using same.
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Compositions and Methods for Modulating Biomass in Energy Crops
Methods for modulating plant biomass are provided. In some embodiments, the methods include the step of modulating in a plant cell the expression of an UPBEAT1 gene product. Also provided are improved energy crop plants, and seeds and parts thereof, which contain a heterologous nucleic acid that enc
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Systems and Methods for Performing Optical Spectroscopy Using a Self-calibrating Fiber Optic Probe
Systems and methods for performing optical spectroscopy using a self- calibrating fiber optic probe are disclosed. One self-calibrating fiber optic probe includes a sensing channel for transmitting illumination light to a specimen and for collecting spectral data of the specimen. The spectral data i
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Autoantibodies in the Detection and Treatment of Cancer
Methods, kits, and compositions for detecting and/or treating cancer based on detecting and/or administering an antibody, which can optionally be a bispecific antibody, having the immunoreaction characteristics of a cancer-associated autoantibody; an antigen for a cancer-associated autoantibody; or
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COMPOSITIONS AND METHODS USING siRNA MOLECULES FOR TREATMENT OF GLIOMAS
The present invention provides small interfering RNA (siRNA) molecules, compositions containing the molecules, and methods of using the compositions to treat gliomas.
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Nicotinic Acid Receptor Ligands
The present invention relates, in general, to nicotinic acid receptor ligands and, in particular, to ligands that have a relative efficacy for activating a G- protein-coupled receptor function (e.g., signaling) that is greater than their relative efficacy for stimulating ss-arrestin function (e.g.,
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RF Controlled Devices to Increase Compliance with Handwashing Protocols
A system for monitoring compliance with handwashing protocols by a plurality of workers, each worker carrying a wireless tag having a worker identifier, the monitoring being performed in a facility having a plurality of areas, the system comprising a plurality of wireless tag reader/transmitters eac
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Fabrication of Metamaterials
An example method of fabricating a metamaterial comprises providing a first metamaterial layer, the first metamaterial layer including a first plurality of conducting patterns, such as electrically coupled resonators. A second metamaterial layer is then formed, including a second plurality of conduc
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Radiolabled Cyclopamine Assay for the Smoothened Receptor
The present invention discloses novel methods for screening compositions for both agonist and antagonist activity on the smoothened receptor. The assay tests ligands on the activity of the receptor using a cyclopamine binding and ultra high receptor expression.
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Chemical Sensors and Methods for Making and Using the Same
A van der Pauw (VDP) sensor comprising an electronic circuit electrically coupled to a surface, the surface comprising a type III-V material, and the electronic circuit measuring a sheet resistivity of the surface using a VDP technique. The VDP sensor may further comprise a macromolecule, such as a
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Xanthine Derivatives for the Treatment of Vascular Depression
Methods and compositions are provided for treating vascular depression. The methods involve administering to a subject in need thereof a xanthine derivative in a therapeutically effective amount to treat vascular depression, particularly the xanthine derivatives pentoxifylline or propentofylline. Th
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Reagent for Autoimmune Disease and Treatment
PROBLEM TO BE SOLVED: To provide a reagent for the treatment of autoimmune diseases and a method. ; SOLUTION: This invention relates to a treatment method using an anti-CD22 monoclonal antibody having specific physiological characteristics. Especially, this invention relates to a method of treating
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Optical Isolator
Various optical isolator embodiments are disclosed. Embodiments comprise a waveguide section utilizing materials that induce a propagation constant shift that is propagation-direction-dependent. Embodiments are characterized by a cutoff frequency for forward propagating waves that is different than
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Photolabile Caged Transition Metal Complexes and Methods of Using the Same
The present invention provides compounds of Formula I: ( I ) along with compositions comprising the same and methods of using the same, such as for photodynamic therapy in the treatment of cancer.
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Cancer Therapy
PROBLEM TO BE SOLVED: To provide cancer therapy. ; SOLUTION: A method for preventing or treating cancer is provided. In the method, low molecular weight antioxidants [e.g., mimetics of superoxide dismutase (SOD)] are generally used in cancer therapy, especially as an active agent or as a chemo- and/
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Single-cell Biosensor for Measuring GPCR Ligand in Test Sample
PROBLEM TO BE SOLVED: To provide a method for measuring the presence and concentration of a GCPR ligand in a test sample including a biological or environmental sample. ; SOLUTION: Provided is the method for the detection of the GPCR ligand in the test sample by using a single cell biosensor express
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Methods and Compositions for Identifying Individuals At Reduced Risk of Sepsis
The present invention provides a method of identifying a subject having a reduced risk of developing sepsis, comprising detecting at least one APOE3 allele in nucleic acid from the subject.
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Methods and Compositions to Identify Increased Risk of Breast Cancer by Detection of CPG Island Methylator Phenotype (CIMP)
The present invention is directed to kits and methods for identifying a female subject as having an increased risk of developing breast cancer, comprising detecting a CPG island methylator phenotype (CIMP) in nucleic acid of the subject.
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Magnetic Resonance Imaging And/or Spectroscopy Contrast Agents and Methods of Use Thereof
The presently disclosed subject matter demonstrates that a spin state which has zero magnetic resonance signal, but an extremely long lifetime, can be used to store magnetization, which can then be recovered into an observable transition. Coupled with hyperpolarization techniques, this permits the p
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Compositions and Methods for Treating Hair Loss Using Non-naturally Occurring Prostaglandins
A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss, reverse hair loss, and promote hair growth.
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Hedgehog Signaling and Cancer Stem Cells in Hematopoietic Cell Malignancies
The present disclosure relates generally to methods of treating hematopoietic cell malignancy in a subject by administering to the subject a Hedgehog (Hh) pathway antagonist, such as a Smoothen (Smo) antagonist alone or in combination with an ABL-kinase antagonist. Specifically, the disclosure relat
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Method of modulating the activity of a nucleic acid molecule
The present invention relates, in general, to agents that modulate the pharmacological activity of nucleic acid molecules and, in particular, to agents that bind therapeutic or diagnostic nucleic acid molecules in a sequence independent manner and modulate (e.g., inhibit or reverse) their activity.
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IgG Fc/HIV-gp120/C3d FUSION PROTEIN
PROBLEM TO BE SOLVED: To provide an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates, and a method for inducing anti-HIV antibodies using the immunogen. ; SOLUTION: There is provided a fusion protein comprising an IgG Fc component, an HIV envelope component,
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