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Characterization of GRP94-ligand Interactions and Purification, Screening, and Therapeutic Methods Relating Thereto
The presently disclosed subject matter discloses characterization of interactions between ligands and Hsp90 proteins, including GRP94, wherein ligand binding to the N-terminal nucleotide binding domain of GRP94 elicits a conformational change that converts the GRP94 from an inactive to an active con
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Apparatuses and Methods for Manipulating Droplets
Apparatuses and methods for manipulating droplets are disclosed. In one embodiment, an apparatus for manipulating droplets is provided, the apparatus including a substrate, multiple arrays of electrodes disposed on the substrate, wherein corresponding electrodes in each array are connected to a comm
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VHH Antibody Fragments for Use in the Detection and Treatment of Cancer
The presently disclosed subject matter provides ligands for detecting and imaging cancer cells and tumors, and for guided delivery of an active agent to cancer cells and tumors. In some embodiments the ligands comprise an antibody fragment, wherein the antibody fragment comprises a VHH domain. In so
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Methods and apparatus for determining body weight and fat content using computed tomography data
Methods and apparatus for determining body weight and fat content using computed tomography data are provided. One method (60) includes acquiring (62) a pre-scan image using a computed tomography imaging system (10) and segmenting (66) the pre-scan image into pixels representing imaged fat and pixel
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High-Speed Multi-Dimensional Beam Scanning System with Angle Amplification
A beam-steering system having high positional resolution and fast switching speed is disclosed. Embodiments of the beam-steering system comprise a diffraction limited optical system that includes a reflective imager and two controllably rotatable MEMS elements. The optical system is characterized by
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Anti-CD19 Antibody Therapy for Transplantation
The invention relates to immunotherapeutic compositions and methods for the treatment and prevention of GVHD, humoral rejection, and post-transplantation lymphoproliferative disorder in human subjects using therapeutic antibodies that bind to the human CD19 antigen and that preferably mediate human
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Methods and Compositions for Modulating Drug-polymer Architecture, Pharmacokinetics and Biodistribution
Drug-polymer chemotherapeutics are provided having improved therapeutic efficacy and reduced dose-limiting toxicity. Methods are also provided for modulating the architecture, pharmacokinetics and biodistribution of drug-polymers and for reducing the dependence of transition temperature on concentra
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Mobile Remote Control of a Shared Media Resource
Systems and methods for controlling a shared media resource are disclosed. One embodiment includes an edge device adapted to control the media resource based on content selection votes received from users in the shared space who transmit their votes to the edge device over a wide area communication
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Transformation-optical Design of Reconfigurable Optical Devices
The design method for complex electromagnetic materials is expanded from form-invariant coordinate transformations of Maxwell's equations to finite embedded coordinate transformations. Embedded transformations allow the transfer of electromagnetic field manipulations from the transformation-optical
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Chronic Lymphocytic Leukemia Prognosis and Treatment
Provided herein are methods for identifying a subject afflicted with chronic lymphocytic leukemia who is responsive to treatment with a chemotherapeutic agent by detecting the presence or absence of at least one APOE4 allele in the subject, the presence of an APOE4 allele identifying the subject as
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Methods of Screening for Risk of Proliferative Disease and Methods for the Treatment of Proliferative Disease
A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Meth
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Treating Oncogenic Ras Driven Cancers
Oncogenic Ras-driven cancer is treated with agent by interrupting pathway comprising activation of Akt by oncogenic Ras, activated Akt causing phosphorylation of eNOS at S1177 site of eNOS to provide activated eNOS in cancer cells and activated eNOS causing activation of wildtype Ras by nitrosylatio
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Resin Assisted Capture of Cysteine-modified Proteins/peptides and Determination of Presence and Location of Modification
A resin connected by amide bond to pyridyl sulfide or methylthiosulfonate can be conjugated to a post-translationally modified protein/peptide to allow determination of presence and kind and optionally location ofcysteine modification(s).
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Anti-CD19 Antibody Therapy for Autoimmune Disease
The invention relates to immunotherapeutic compositions and methods for the treatment of autoimmune diseases and disorders in human subjects using therapeutic antibodies that bind to the human CD19 antigen and that preferably mediate human ADCC. The present invention relates to pharmaceutical compos
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Indoles, Derivatives, and Analogs Thereof and Uses Thereof
Indole derivatives and analog compounds and pharmaceutical compositions comprising the same are provided. Also provided are methods of using these compounds to inhibit tubulin polymerization in a cell associated with a proliferative disease or to treat a cancer.
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Compositions for Tissue Repair/regeneration
The invention provides compositions and methods for cardiac repair and/or regeneration of tissues such as myocardium.
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Predicting Responsiveness to Cancer Therapeutics
Provided herein are methods for predicting the responsiveness of a cancer to a chemotherapeutic agent using gene expression profiles. In particular, methods for predicting the responsiveness to 5-fluorouracil, adriamycin, cytotoxan, docetaxol, etoposide, taxol, topotecan, PB kinase inhibitors and Sr
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Geranylgeranyl Transferase Inhibitors and Methods of Making and Using the Same
The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
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Droplet Actuators, Systems and Methods
A droplet actuator with arrays of electrodes electrically coupled to a number of controllable voltage sources that is less than the number of electrodes. A method of defining partitions for pin layouts in a droplet actuator for a specific assay, the method including: defining droplet traces for the
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Compositions and Methods for the Treatment of Seborrhea
Methods and compositions are provided for treating dermatological diseases, disorders, and pathologies, including seborrheic dermatitis, in a subject in need thereof. In some embodiments, methods are provided for the treatment of a dermatological disease, disorder, or pathology comprising, topically
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Method for Augmenting the Effects of Serotonin Reuptake Inhibitors
A method of treating a subject for a serotonergic neurotransmission dysregulation disorder, comprises administering the subject a serotonin enhancer (e.g., a serotonin reuptake inhibitor) in an amount effective to treat the disorder; and concurrently administering the subject 5-hydroxytryptophan in
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Metamaterial Microwave Lens
A metamaterial microwave lens having an array of electronic inductive capacitive cells in which each cell has an electrically conductive pattern which corresponds to incident electromagnetic radiation as a resonator. At least one cell has a first and second electrical sections insulated from each ot
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Use of Ranolazine for Non-cardiovascular Disorders
Disclosed is a method of treating a non-cardiovascular disorder characterized by an abnormal persistent sodium current in a subject in need of treatment thereof, said method comprising administering to the subject an effective amount of a compound of Formula (I): wherein: m is 1 or 2; R1, R2, R3, R4
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Detection Assay Devices and Methods of Making and Using the Same
An article such as a biomolecular detector or biosensor having a nonfouling surface thereon includes:(a) a substrate having a surface portion; (b) a linking layer on the surface portion; and (c) a polymer layer formed on the linking layer; and (d) a first member of a specific binding pair (e.g., a p
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Inhibiting Smad signaling promotes neuron regeneration
Regeneration of a lesioned CNS axon of a mature neuron, determined to be subject to regeneration inhibition by Smad2/3 signaling, is promoted by contacting the neuron with an inhibitor of Smad2/3 signaling sufficient to promote regeneration of the axon.
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Plasmonic Assisted Systems and Methods for Interior Energy-activation from an Exterior Source
A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The i
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Anti-CD19 Antibodies and Uses in Oncology
The invention relates to immunotherapeutic compositions and methods for the treatment of B cell diseases and disorders in human subjects, such as, but not limited to, B cell malignancies, using therapeutic antibodies that bind to the human CD19 antigen and that preferably mediate human ADCC. The pre
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Single-cell biosensor for the measurement of GPCR ligands in a test sample
The present invention is related to the detection of GPCR ligands in a test sample by using a single cell biosensor expressing a GPCR. Preferably, the test sample is derived from a biological or environmental sample. This invention may be used to detect the presence of a disease or to detect the pre
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Methods and Compositions for Predicting Success in Addictive Substance Cessation and for Predicting a Risk of Addiction
The present invention relates to genetic polymorphisms that are associated with dependence on an addictive substance. In particular, the present invention relates to a method for predicting success in addictive substance cessation in a subject, such as predicting success in nicotine cessation. In so
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Aptamer Inhibitors of Osteopontin and Methods of Use Thereof
The present invention polynucleotide aptamers that selectively bind to and inhibit the function of osteopontin, pharmaceutical compositions comprising the same, and methods of use for diagnostics and treatment of diseases and disorders associated with osteopontin.
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Vaccine Vectors
The present invention relates, in general, to recombinant viral constructs expressing a protective antigen and to vaccine compositions comprising same. The invention further relates to a method of inducing an immune response, for example, to human immunodeficiency virus (HIV).
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Antidotes for Agonistic Aptamers
The present invention relates, in general, to aptamers and antidotes therefor and, in particular, to aptamers capable of binding to and activating molecules, such as receptors (e.g., the OX40 receptor) and enzymes. The invention further relates to antidotes to such agonistic aptamers. The invention
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Biomolecular nano device
Methods for measuring environmental parameters using chemical recording are provided. In some embodiments, the methods include generating a polymer comprising an ordered series of chemical units, wherein the position and number of each chemical unit in the polymer is indicative of a reading of the e
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Fluorescent Prochelators for Cellular Iron Detection
Fluorescent probe compound of Formula Ia or Formula Ib: are described, along with methods of using the same to detect iron, copper, and hydrogen peroxide.
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Signatures of Radiation Response
The present invention relates, in general, to gene expression profiles, and in particular, to a peripheral blood gene expression profile of an environmental exposure, ionizing radiation. The invention further relates to methods of screening patients for radiation exposure based on gene expression pr
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Non-invasive Systems and Methods for In-situ Photobiomodulation
Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extra
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Anti-Tumor Antibodies
Chondroition sulfate proteoglycans represent excellent targets for anti-tumor immunotherapy. Antibodies which target such proteoglycans can be used alone, in combinations, armed with a cytotoxic payload or unarmed. Combinations of such antibodies can target different epitopes of the proteoglycans. I
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Dual Specific Immunotoxin for Brain Tumor Therapy
We tested the in vitro and in vivo efficacy of a recombinant bispecific immunotoxin that recognizes both EGFRwt and tumor-specific EGFRvIII receptors. A single chain antibody was cloned from a hybridoma and fused to toxin, carrying a C-terminal peptide which increases retention within cells. The bin
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Dose of an Angiogenic Factor and Method of Administering to Improve Myocardial Blood Flow
The present invention has multiple aspects. In one aspect, the present invention is directed to a unit dose pharmaceutical composition comprising from about 5 ng/dose to less than 135,000 ng of an angiogenic agent, typically from 5 ng to 67,500 ng. Preferably, the angiogenic agent is FGF, more prefe
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Near Infrared Doped Phosphors Having an Alkaline Gallate Matrix
Phosphors based on doping of an activator (an emitter) into a host matrix are disclosed herein. Such phosphors include alkaline gallate phosphors doped with Cr3+ or Ni2+ ions, which in some embodiments can exhibit persistent infrared phosphorescence for as long as 200 hours. Such phosphors can be us
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Near Infrared Doped Phosphors Having a Zinc, Germanium, Gallate Matrix
Phosphors based on transition metal-activated gallates, particularly Cr3+- and Ni2+-activated zinc germanium gallates, are disclosed herein. In some embodiments such phosphors can exhibit persistent infrared phosphorescence for as long as 400 hours. Such phosphors can be used, for example, as compon
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Method of identifying therapeutic agents
The present invention relates to a method of identifying agents suitable for use in treating epilepsy and other brain disorders, including but not limited to bipolar disorder, schizophrenia and depression. The invention further relates to methods of treatment based on the use of agents so identifiab
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Coded Aperture Snapshot Spectral Imager and Method Therefor
The present invention enables snap-shot spectral imaging of a scene at high image generation rates. Light from the scene is processed through an optical system that comprises a coded-aperture. The optical system projects a plurality of images, each characterized by only one of a plurality of spectra
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Genetics Variants Associated with HIV Disease Restriction
The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to genetic variants associated with restriction of HIV disease progression.
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Methods and Compositions for Molecular Imaging
Methods for imaging a target cell, tissue, or organ in a subject. In some embodiments, the methods include the steps of (a) administering to the subject a contrast agent that includes a paramagnetic or superparagmanetic material and a targeting moiety that targets the contrast agent to the cell, tis
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Aptamers as agonists
Nucleic acid aptamers are described herein which can transduce a signal into cells by crosslinking a cell surface molecule, thereby inducing of one or more biological activities by the cells; in serving as agonists.
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No-modified hemoglobins and uses therefor
Nitrosylhemoglobin can be produced by introducing gaseous NO into an aqueous solution of hemoglobin. It has been demonstrated that nitrosylhemoglobin in aqueous solution can be converted to SNO-hemoglobin upon introduction of oxygen to the solution, as is postulated to occur in the lungs. Nitrosylhe
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Glycoprotein Cancer Biomarker
The invention relates to glycoproteins having a cancer-specific glycoform. Cancer-specific glycoforms are useful in diagnostics and therapeutics.
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Prophylactic and Therapeutic Immunization Against Protozoan Infection and Disease
Polypeptide and polynucleotide vaccines effective to treat or prevent infection of a mammal, such as a dog, a cat, or a human, by a protozoan. Methods of treatment and prevention are also provided, including therapeutic administration of the vaccine to an infected mammal to prevent progression of in
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Microbial Production of Pyruvate and Pyruvate Derivatives
Microbial production of pyruvate and metabolites derived from pyruvate in cells exhibiting reduced pyruvate dehydrogenase activity compared to wild-type cells. Acetate and glucose are supplied as a carbon sources.
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Anti-trypanosomal Peptides and Uses Thereof
The present invention provides methods of killing, inhibiting the growth, and/or inhibiting the reproduction of kinetoplastid protozoan with hydrophobic signal sequence peptides and compositions including such hydrophobic signal sequence peptides.
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Mixotrophic Algae for the Production of Algae Biofuel Feedstock on Wastewater
The disclosure encompasses, among other aspects, mixed algal populations able to survive and proliferate on culture media that have a high proportion of an industry wastewater. In particular, at least one strain of an alga in the algal population proliferates mixotrophically. Embodiments further enc
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Heparan Sulfate Synthesis
The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in numerous ways to produce a range of oligosac
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Method to Alter Sex Ratios in Avian Offspring
The present invention includes methods of influencing the sex chromosome ovulated by a female bird and altering the sex ratio in avian offspring by altering the exposure of an ovulating female bird to one or more stress hormones. In some aspects, the method includes exposing an avian female to a glu
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Roduction of Higher Quality Bio-oils By In-line Esterification of Pyrolysis Vapor
The disclosure encompasses in-line reactive condensation processes via vapor phase esterification of bio-oil to decease reactive species concentration and water content in the oily phase of a two-phase oil, thereby increasing storage stability and heating value. Esterification of the bio-oil vapor o
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Protein Markers Identification for Gastric Cancer Diagnosis
Methods for detecting cancer as well as methods of diagnosis of cancer by detecting proteins secreted into biological fluids are disclosed The invention was first applied to detecting proteins secreted into serum and urine However, it is understood that the methods have broader application to develo
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Methods and Compositions for Ophthalmic Treatment of Fungal and Bacterial Infections
The present invention provides methods and compositions for use in the methods for contacting an eye of a patient with an effective amount of therapeutic composition comprising a pharmaceutically acceptable chelating agent, a pharmaceutically acceptable pH buffering agent, and an antimicrobial agent
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Modified Peptides Having Toxin-enhancing Effects.
This invention relates in part to modifying BtBooster (BtB) peptides, in part to increase their stability in insect midgut digestive juices. Some preferred embodiments of BtB have removed proteinase cleavage sites resulting in increased stability of the modified BtB in the insect gut, while retainin
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Non-invasive Methods and Apparatus for Detecting Insect-induced Damage in a Plant
Lesions caused by insects feeding on plants are associated with the generation of regions of blue-green fluorescence in such as the cotton boll carpel wall and in the lint region. The present disclosure now provides methods and devices to rapidly and non-invasively detect and measure the insect-rela
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Composition À Base De Mycoplasma Gallisepticum
The present invention provides a formulation that prevents virulent Mycoplasma galHsepticum infection in birds of the order GaIHf ormes. The formulation comprises live Mycoplasma galHsepticum strain K5831 or derivatives thereof in a pharmaceutically acceptable carrier. A vaccine that prevents virule
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Vaccine for Runting-stunting Syndrome
The present invention includes polypeptides, polynucleotides, antibodies, and vaccines associated with Runting Stunting Syndrome (RSS) in poultry. The present invention also includes methods of protecting poultry, including chickens, against RSS by immunization with such polypeptides and vaccines.
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Preparation of Alkenes By Mild Thermolysis of Sulfoxides
Embodiments of this disclosure, among others, encompass methods for generating alkenes under mild thermolytic conditions that can provide almost total conversion of a precursor compound to an alkene without isomerization or the need to chromatographically purify the final product By selectively bloc
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Biochars, Methods of Using Biochars, Methods of Making Biochars, and Reactors
Embodiments of the present disclosure provide for biochar impregnated with microbes, methods of making biochar impregnated with microbes, methods of using biochar impregnated with microbes, methods of using biochar to produce gas, reactors using biochar and/or biochar impregnated with microbes, meth
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Recombinant Avian Paramyxovirus Vaccine and Method for Making and Using Thereof
The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV; modified APMV prepared by such methods; DNA
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Antimicrobial Composition and Use
Antimicrobial compositions are provided comprising a pharmaceutically acceptable organic acid and a pharmaceutically acceptable surfactant. This synergistic combination allows compositions to be formulated at low concentrations that have efficacy in reducing bacterial counts by greater than 3 log wi
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Development of Herbicide-resistant Grass Species
The invention relates to a selected and cultured ACCase inhibitor herbicide-resistant plant -resistant plant from the group Panicodae, or tissue, seed, or progeny thereof, and methods of selecting the same. The invention also relates to methods for controlling weeds in the vicinity of an ACCase inhi
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Substrate-selective Co-fermentation Process
Biological method for conversion of a sugar-containing organic material into a desired biochemical product. Use of a plurality of substrate-selective cells allows different sugars in a complex mixture to be consumed concurrently and independently. The method can be readily extended to remove inhibit
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Vectors Comprising a Magnum-specific Promoter for Avian Transgenesis
This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which e
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Methods and Compositions for Degrading Pectin
The present invention provides enriched polynucleotides, and enriched polypeptides having pectinase activity. The present invention also includes methods of using the polynucleotides and polypeptides described herein. For instance, the methods include producing a metabolic product, such as ethanol.
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Yeast Cells and Methods for Increasing Ethanol Production
Provided herein are methods for producing ethanol using yeast to ferment pretreated solid lignocellulosic materials such as pretreated solid lignocellulosic materials obtained from softwoods like pine. The pretreated solid lignocellulosic material is present at a concentration of at least 12% solids
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2'-fluoro-6'-methylene Carbocyclic Nucleosides and Methods of Treating Viral Infections
The present invention relates to 2'-Fluoro-6'-methylene carbocyclic nucleosides, pharmaceutical compositions containing these nucleosides and their use in the treatment or prophylaxis of a number of viral infections and secondary disease states and conditions thereof, especially including Hepatitis
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Pyridinone Hydroxycyclopentyl Carboxamides: HIV Integrase Inhibitors with Therapeutic Applications
New chiral and achiral oxy- substituted cyclopentyl pyridinone diketocarboxamides and their derivatives and methods for their preparations are disclosed. The compounds include tautomers, regioisomers and geometric isomers. These complex carboxamides are designed as inhibitors of HIV replication thro
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Antimicrobial Compositions and Methods of Use
Disclosed herein are antimicrobial compositions, kits, and articles of manufacture. Further disclosed herein are methods for treating surfaces, including tissue, inter alia, wounds, with the disclosed compositions.
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Hybridoma Cell Lines and Monoclonal Antibodies Recognizing Anthrose Saccharide of Bacillus Anthracis
The present invention includes hybridoma cell lines and monoclonal antibodies that bind to the anthrose tetrasaccharide of Bacillus anthracis and methods using said antibodies.
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Induction and Stabilization of Enzymatic Activity in Microorganisms
Provided herein are methods for inducing and stabilizing an enzyme activity. Optionally, the enzyme is in a microorganism capable of producing the enzyme. In some embodiments, the enzyme can be nitrile hydratase, amidase, or asparaginase I. Provided are compositions comprising enzymes or microorgani
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Biological-based Catalyst to Delay Plant Development Processes
The present invention is directed to methods for delaying a plant development process comprising exposing a plant or plant part to one or more bacteria or enzymes. In specific embodiments, the one or more bacteria are selected from the group consisting of Rhodococcus spp., Pseudomonas chloroaphis, B
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PROKARYOTIC RNAi-LIKE SYSTEM AND METHODS OF USE
Provided herein are methods for inactivating a target polynucleotide. The methods use a psiRNA having a 5' region and a 3' region. The 5' region includes, but is not limited to, 5 to 10 nucleotides chosen from a repeat from a CRISPR locus immediately upstream of a spacer. The 3' region is substantia
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Microbial production of alanine
Microbial production of pyruvate and metabolites derived from pyruvate in cells exhibiting reduced pyruvate dehydrogenase activity compared to wildtype cells. Acetate and glucose are supplied as a carbon sources.
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Enhancement of Bacillus Thuringiensis Cry Toxicities to Lesser Mealworm Alphitobius Diaperinus
The subject invention relates in part to the discovery that BtBooster (BtB) peptides enhance Bt strain and Cry protein toxicity to the lesser mealworm. The subject invention also relates in part to the discovery that Bt tenebrionis producing Cry3Aa crystals and Bt japonensis BuiBui producing Cry8Ca
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Fabrication of microstructures integrated with nanopillars along with their applications as electrodes in sensors
This invention presents microstructures enhanced with nanopillars. The invention also provides ways for manufacturing nanopillar-enhanced microstructures. In some embodiments, the invention also provides methods of use for the nanopillar-enhanced microstructures.
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L- OddC Prodrugs for Cancer
The main drawback in the use of most nucleoside anticancer agents originates from their hydrophilic nature, of which property requires a high and frequent dosage for an intravenous administration. Unlike other nucleoside anti-tumor agents, troxacitabine appears to predominantly enter tumor cells by
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Southern Highbush Blueberry Plant Named 'TH-682'
The new variety 'TH-682' is provided. The new and distinct variety ripens early compared to rabbiteye varieties generally available to homeowners and produces an abundance of attractive, light blue fruit that are generally large and have good flavor. The plant of the new variety 'TH-682' is vigorous
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Litter Receptacle
A litter receptacle system, including: a support frame; a container for receiving and storing litter; a coupler; and a retention device; wherein the coupler rotatably couples the container to the support frame; the retention device is in communication with the support frame and the container; and th
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Pennisetum 'Tift-23'
The new variety Pennisetum 'Tift-23' is provided. The new and distinct variety has increased tillers under drought conditions; superior Helminthosporium leaf spot resistance; high ornamental value; narrow canopy; narrow base; and narrow leaves. The asexually reproduced inter-specific variety is reli
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Pyridinone Diketo Acids: Inhibitors of HIV Replication in Combination Therapy.
A new class of diketo acids constructed on pyridinone scaffolds, designed as inhibitors of HTV replication through inhibition of HIV integrase, is described. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS and ARC, either as the compounds, o
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Reverse Restriction Fragment Length Polymorphism Assay and Uses Thereof
The present invention presents a Reverse Restriction Fragment Length Polymorphism (RRFLP) method for the detection of the presence of an informative restriction enzyme site in a nucleotide sequence. The method includes digesting a sample with the informative restriction enzyme; performing polymerase
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Phosphorescent Compositions, Methods of Making the Compositions, and Methods of Using the Compositions
Compositions, methods of making compositions, materials including compositions, crayons including compositions, paint including compositions, ink including compositions, waxes including compositions, polymers including compositions, vesicles including the compositions, methods of making each, and th
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Nanostructure-Enhanced stereo-electrodes for fuel cells and biosensors
This application provides nanostructure-enhanced stereo-electrodes. The application also provides novel ways to manufacture nanostructure-enhanced electrodes. In some embodiments, the invention also provides methods of use for devices equipped with the nanostructure-enhanced stereo-electrodes.
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Neuronal progenitors from feeder-free human embryonic stem cell culture
The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder cell-free neuroprogenitor cells, preferably human cells themselves, as well as methods for producing feede
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Paenibacillus Ssp. and Methods for Fermentation of Lignocellulosic Materials
Provided herein are methods for producing a fermentation product, such as ethanol, by co-culture of a member of the genus Paenibacillus and an ethanologenic microbe, such as yeast or E. coli. Also provided are methods for making enzymes useful in the saccharification of a pretreated lignocellulosic
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Synthesis and Stabilization of Neutral Compounds with Homonuclear Bonds
The present invention is directed to the synthesis and stabilization of neutral molecules containing homonuclear single or multiple bonds, methods of preparation, and uses thereof.
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Nematode Resistant Transgenic Plants
Compositions and methods for providing nematode resistance are provided. One aspect provides transgenic plants or cells comprising an inhibitory nucleic acid specific for one or more nematode esophageal polypeptides. Other aspects provide transgenic plants or cells resistant to at least two differen
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Compositions and Methods Useful for Site-directed Recombination in Plants.
This invention relates generally to useful compositions and methods related to plant site-directed recombination. In particular, the invention relates to novel nucleic acid sequences unique to a portion of the sorghum NBS-LRR region, as well as vectors, seeds, plant parts and plants comprising these
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Methods, Microorganisms, and Compositions for Plant Biomass Processing
Disclosed herein are methods of degrading plant biomass, and microorganisms and polypeptides used in such methods, hi certain embodiments, the methods include growing Anaerocellum thermophilum on a substrate that comprises plant biomass under conditions effective for the A. thermophilum to convert a
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Biotin-facilitated transport in gram negative bacteria
Biotinylation of compounds such as peptides and peptidomimetics facilitates illicit transport of the compounds into Gram negative bacteria.
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Switchgrass Cultivar EG1101
A switchgrass cultivar designated EG1101 is disclosed. Also disclosed are seeds of switchgrass cultivar EG1101, plants of switchgrass EG1101, plant parts of switchgrass cultivar EG1101 and methods for producing a switchgrass plant produced by crossing switchgrass cultivar EG1101 with itself or with
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Cas6 Polypeptides and Methods of Use
Provided herein are methods for cleaving a target RNA polynucleotide. The target RNA polynucleotide includes a Cas6 recognition domain and a cleavage site, and may be based on a repeat from a CRISPR locus. The methods may be practiced in vivo or in vitro. Also provided are polypeptides that have Cas
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Photocatalytic Structures, Methods of Making Photocatalytic Structures, and Methods of Photocatalysis
Embodiments of the present disclosure include structures, photocatalytic structures, and photoelectrochemical structures, methods of making these structures, methods of making photocatalysis, methods of splitting H2O, methods of splitting CO2, and the like
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Plant Production and Delivery System for Recombinant Proteins As Protein-flour Or Protein-oil Compositions
The present invention relates to a plant flour material comprising a ground, dried plant material, wherein the plant material contains a recombinant protein comprises a bactericidal or an insecticidal protein toxin, or combinations thereof. The present invention further relates to a seed oil body co
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Methods and Systems for Analyzing Ratiometric Data
Systems and methods for analyzing ratiometric data, e.g., ratiometric image data such as fluorescent image data.
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