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A New Protocol of Diels-Alder Lattice Hardening for Highly Efficient Electro-optic Materials Showing Outstanding Temporal Stability over 200 Degrees C

Introduction Organic electro-optic (EO) materials have attracted much interest in the past two decades because of their extensive potential applications in various fields, ranging from waveguides, switches, emitters, and detectors. Though EO materials have a huge potential in Photonics and Electroni
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Fossil Resin Flotation from Coal by Selective Coagulation and Depression of Coal

Natural resins are generally separated from coal by froth flotation. The resins are important commercially, being used for adhesives, varnishes, coatings, waterproofing, linoleum, etc. Extracting resin from resin-bearing coal is important in Western North America where certain cola fields contain si
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Use of CTLA4Ig for Improved Adenovirus-mediated Gene Therapy

Introduction Gene therapy holds great promise for the treatment of many diseases that now lack specific therapies. The primary goal of gene therapy is to introduce additional genetic elements or to replace missing nonfunctional molecular elements in the DNA of a living cell so as to target and repai
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Production of Palladium Nanostructures with Shape Selection by Adding Bromide

Introduction Single-crystal, one-dimensional nanostructures of palladium are attractive as interconnects for fabricating nanoscale electronic devices. Polycrystalline, mesoscopic wires made of palladium have been utilized for resistance-based detection of hydrogen gas. However, polycrystalline wires
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Method for Generating Human Retinal Neurons and Photoreceptors from Embryonic Stem Cells

Introduction The degeneration of neurons and photoreceptors in the retina occur in a number of disorders for which there are currently few therapies, including retinitis pigmentosa, age-related macular degeneration, and glaucoma. Although retinal regeneration is robust in lower vertebrates, regenera
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Molecular Encoding of Nucleic Acid Templates for Pcr and Sequence Analysis

Introduction The polymerase chain reaction (PCR) allows multiple copies of selected DNA sequences to be produced from limited amounts of a DNA template. Reactions with limited amounts of template, however, increase the risk of amplifying contaminant DNA and can also result in a skewed yield of PCR p
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Method of enhancing expression of recombinant proteins

Introduction Large scale production of industrially and medically important proteins is achieved using “expression systems”, whereby a gene encoding the protein of choice is introduced into a cell (e.g. yeast or bacterial) that is optimized for high-yield expression. Many proteins are poorly produc
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Polymer Solar Cells using Self-Assembled Monolayer modified Zinc Oxide/Metal as Cathodes

Introduction Conjugated polymer-based organic solar cells are considered an essential source of inexpensive renewable energy due to their advantages of being fabricated by low-cost and large-area printing and coating techniques on light-weight flexible substrates. Bulk heterojunction (BHJ) solar cel
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Thin-film Bioreactor

Introduction The large scale production of biological materials requires the use of bioreactors. Bioreactors can also be used in biologically mediated chemical conversions and waste management. Traditionally, bioreactors are difficult to fully automate and require labor intensive maintenance to func
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Intracellular Delivery Vector

Introduction Some drugs require cellular uptake to be effective and methods to increase cellular uptake are desired to improve on the efficacy and reduce the side-effects of certain drugs. One way to increase cellular uptake of a drug is by attaching it to a cellpenetrating peptide (CPP). CPPs, such
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Cycling Ligand Adsorber

Introduction Water contaminated with heavy metals is detrimental to both the environment and human health. Heavy metal contamination commonly arises from many industrial processes. Removal of heavy metals from wastewater is a key part of environmental cleanup operations and is vital for regulatory c
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Electrochromic “Smart” Windows

Introduction Coatings for optical glass and vision products have been on the market for several decades. The older coatings change from transparent to colored under the effect of ultra-violet radiation. Newer coatings have been developed whose transparency can be changed electrically. But these inor
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Coiling/Uncoiling Actuators

Introduction Shape memory alloys (SMA) are metals which can return to their original shape after deformation through the application of heat. They are in wide use for applications ranging from cardiovascular stents to reversible energy-absorbing bumpers for automobiles. SMA’s take advantage of the m
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New Method and Compositions for Improvement of Nuclear Magnetic Resonance Spectroscopy

Highlights New methodology creates ability to easily examine molecular structure of complex mixtures Uses easily available materials as well as novel formulations of specifically tailored solvent mixtures and/or modified chromatographic media Unique application of known molecular chemical princip
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Weaver for Hybrid Nanomaterials

Introduction Nanomaterials possess unique qualities (e.g. strength, lightweight) that make them desirable for numerous applications. Hybrid structures combine two or more materials to give the final structure qualities of both component materials. By using an electric field in conjunction with capil
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Electrochromic Smart Window

Introduction Electrochromic materials change color in response to changing voltage. Used in conjunction with glass or plastic, this property allows for complete control over light transmission, easily converting between transparent and opaque and all shades in between. This technology could have a p
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Design of coiled ferromagnetic composite plate spring

Introduction In general, motors are constructed by both electro and permanent magnets, and move due to the attractive magnet using force, which originates from these magnets. The motors rotate infinitely in principal; however the output torque is limited. Technology description Researchers at the UW
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Design of Space Structures Made of Shape Memory Alloys for Stowability and Shape Control

Introduction Shape memory alloy (SMA) materials superelasticity and shape memory facilitate their use in stowable building units for space structures. With tight space allocation restrictions on vehicles, compactable structures present a viable alternative to standard structures whose size cannot be
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Biocompatible Non-fouling Materials with Active Functional Groups

Introduction As combination medical device/pharmaceutical products become more widespread, one big challenge is to find materials that are both biocompatible and chemically active. For example, it is desirable that drug delivery carriers, tissue scaffolds, and biosensor surfaces all have functional
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Design of Bio-Actuator for Medical Treatment Based on Ferromagnetic Shape Memory Alloy Helical Spring

Introduction FSMA (ferromagnetic shape memory alloy) materials provide fast speed of actuation using magnetic fields and large strain and stress capability. Technology description Researchers at the University of Washington have developed applications for FSMA devices in stents encapsulated with mic
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Advanced Biomimetic Surfaces for Surface-Enhanced Raman Spectroscopy (SERS)

Introduction Raman spectroscopy characterizes molecules by their Raman scattering. As incoming light scatters off a molecule, most does so elastically, neither gaining nor losing energy, and this is known as Rayleigh scattering. Some of this light, however, about 1 in 10 million photons, is the subj
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Superlow Fouling Materials and Surfaces Comprising Molecular-Scale Mixed Charged Species

Introduction Superlow fouling materials and surfaces that can resist protein adsorption, cell adhesion, biofilm formation, and microorganism settlement are needed for the improvement of a variety of health-related products. Ideallly, any synthetic surface that comes into contact with body fluids or
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Design of Active Materials and Structures based on Composites of Shape Memory Alloy and Shape Memory Polymer

Introduction Shape memory alloys (SMA) and shape memory polymers (SMP) have shown tremendous promise for a wide variety of applications because of their ability to “remember” a previous state when heated. However, they can only remember a single shape. The ability to remember two shapes would make t
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Energy Harvesting Composite Made of Piezoelectric Energy Harvesting Composite Made of Piezoelectric

Introduction Shape memory alloy (SMA) materials are easily deformed at low temperature and return to their original configuration by heating. Via the piezoelectric effect, some materials will produce an electric potential as a result of stress from changes in temperature. The alternating current (AC
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Crosslinkable Hole Transporting Materials for Organic Light emitting

Introduction High-performance organic or polymer light-emitting diodes comprise multilayer configurations having hole-transporting, emissive and electron-transporting layers to balance the injection and transport of both holes and electrons. In general, holetransporting material is the first applied
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Design of Fish Fin Actuators Based on Shape Memory Alloys

Introduction Shape memory alloys (SMA) are metals which can return to their original shape after deformation through the application of heat. They are in wide use for applications ranging from cardiovascular stents to reversible energy-absorbing bumpers for automobiles. SMA’s take advantage of the m
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Improved Design of FSMA Inchworm Actuator

Introduction There is great demand for new, compact, but powerful actuators in a variety of industries which can replace heavy actuators, such as the hydraulic actuator and the electrical motor with gear box. Technology description Researchers at the UW have developed an improved design of a ferroma
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Production of Thick Microcellular & Thermoplastic Sheets and Components

Introduction Thick microcellular plastics for lightweight, energy efficient building materials and other applications have been developed. Up to 70% reduction in relative density of the materials has been achieved. Technology description Researchers at the UW have developed a process to make thick,
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Nanocellular, Microcellular, and Macrocellular Foams from TPU’s and TPE’s and their Method of Manufacture

Introduction Thermoplastic Elastomers (TPE’s) are a class of flexible materials with a wide range of applications. To date TPE’s, and a subclass of these materials, Thermoplastic Urethanes (TPU’s), have been difficult to foam by conventional means. Technology description Researchers at the UW have d
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Super-low Fouling Zwitterionic-based Materials

Introduction Tin-based antifouling paints are being phased out due to marine pollution concerns. Non-toxic silicone and fluorinated coatings are under development, but these are easy release coatings rather than antifouling. PEG is the most commonly used antifouling polymer coating, but its suscepti
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Electroactive Polymer Using Shape Memory Alloy

Introduction Shape memory polymers have shown tremendous promise for a wide variety of applications for their ability to “remember” a previous state when heated. Unfortunately, they have been slow to develop commercial availability. Many of these polymers also have small compression ratios. However,
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Ferromagnetic Shape Memory Alloys

Introduction Shape Memory Alloys (SMA) are metals which return to their original shape after deformation. Conventional SMAs are thermally activated, requiring heat to change the metal’s crystal structure and allow it to resume its pre-deformation shape. Technology description Material scientists at
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Biochemical Sensor in Open Nanochannel

Introduction Micro and nano-sized biochips are convenient for exploring molecular interactions because of their small feature size. The small size of the chips allows for sensitive detection on the molecular level while reducing testing time and sample volumes. Technology description Researchers at
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Mechanosensor Based on Arrayed Dome-shaped Flemion

Introduction Mechanosensors are found throughout nature, for example, in both plant and animal tissue, specific cells are capable of sensing mechanical movement. Remarkably, some cells sense mechanical forces in three dimensions. Mimicking these types of sensors with human-made materials represents
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Novel Compound Semiconductor Use as a Buffer Layer for Controlled Oxide Growth on Silicon

Introduction An area of research that has gained increasing importance in recent years is the controlled growth of oxides other than SiO2 on silicon. Technology description Researchers at the UW have developed the use of Ga2Se3 as a novel buffer layer preventing SiOx and silicide formation during th
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A novel graded-modulus-interphase material for polymeric composites

Introduction Filler- (e.g., particulate or fiber) reinforced structural polymers or polymeric composites have changed the way things are made. Today, they are found, for example, in air/ground transportation vehicles, sporting goods, ballistic barrier applications and weapons, electronic packaging,
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Microcellular Poly (vinyl Chloride) Structures

Introduction A novel process for continuous production of microcellular foams has been developed and applied to make microcellular profiles from PVC. Technology description Researchers at the UW have developed microcellular poly (vinyl) chloride polymeric structures made in an extrusion or injection
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Methods for Production of Thick Microcellular Sheets and Composite Structures

Introduction Microcellular manufacturing processes have been developed largely for production of thin films (thickness
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3-D Tissue Culture Chamber

UW Ref# 7654 Introduction Many of the seminal findings in cell and molecular biology have come from cultures of cells grown in two dimensions but the limitations of biology in just 2D are becoming clear. Cells in tissue are not just autonomous masses but consist of many interdependent cell types and
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Carbon Nanotube-based Thermal Interface Material

Introduction Thermal management is an increasingly serious challenge for the semiconductor device industry as the density of circuit elements continues to increase in accordance with Moore’s Law. Effective methods to remove heat are essential to proper packaging and operation of next generation inte
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Electrochemical Printing for 2 & 3 Dimensional Rapid Fabrication

Introduction Electrochemical Fabrication is the process of manufacturing a wide array of devices by either electrodeposition of pure metal/alloys on substrates or by selectively producing and/or removing material from the substrate through the use of spatially controlled electrochemical reactions. M
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Toughening Structural Adhesives Using Novel Core-Shell Thermoplastic Nanoparticles

Introduction Structural Adhesives are increasingly replacing traditional fastening methods such as welding, bolts and rivets, in industrial applications. They are used to bond many different material types including ceramics, metals, glass, plastics and composites, and are designed for high strength
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Design of Thermal Interface Material Based on High Temperature Shape Memory Alloy for Connecting Two Thermoelectric Legs

Introduction Efficient heat management is crucial for electronics to optimize performance and to avoid premature component deterioration. An area of primary concern is at the interface of adjoining thermal components, such as with heatsink interfaces and with connections between thermoelectric legs.
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Osmium based Organic Light Emitting Diodes (OLEDs)

Introduction OLED-based displays are being incorporated into digital cameras and cell phones. Bright, vivid colors and a wide viewing angle are the key advantages of these OLED displays. Current OLED technologies and products are susceptible to water and oxygen reactivity damage and exhibit low effi
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Design of Spring Actuators Based on Ferromagnetic Shape Memory Alloys and Composites

Introduction Shape memory alloys (SMA) and ferromagnetic shape memory alloys (FSMA) have shown tremendous promise for a wide variety of applications because of their ability to “remember” a previous state when either heat or a magnetic field is applied, respectively. This is especially important fo
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Thulium-Doped Fiber Laser Amplifier at 1762 nm

Introduction The role of a fiber amplifier is to increase the signal from an optical source, such as a laser, and this function is vital for effective telecommunications. In practice, this fiberoptic component is pumped with energy corresponding to a specific wavelength range, and the original optic
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Quantum Dot Waveguides

Introduction Realization of ultrahigh-density photonic integrated circuits requires the ability to guide light at subdiffraction limit dimensions without extensive loss due to sharp waveguide bending. Existing technologies may be difficult to integrate with optical and electronic components on chip,
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Microcellular Foaming of Cyclic Olefin Copolymer (COC)

Introduction Cyclic olefin copolymer (COC) is a commercially available thermoplastic. It possesses exceptional clarity in its natural form, similar to that of glass, and it has high moisture resistance and low absorption rates. This thermoplastic’s many qualities make it an exceptional candidate for
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Continuous Production of Microcellular Fibers

Introduction In microcellular plastic foams, inert gas is dissolved in thermoplastic under high pressure. The forced evacuation of this gas during processing creates pores (or cells) within the final plastic. The pores are small enough that clarity of the plastic is unaffected, and because of the po
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Neutral Conjugated Surfactants as Electron Injection Layer in Polymer Light-emitting Diodes

Introduction Significant improvements have been made in polymer light-emitting diode (PLED) technology, including improved efficiency, high brightness, and low drive voltage. Despite advances, operational stability remains a challenge for PLED technology. There still remains a need for an efficient
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Solution Processable n-Type polymers

Introduction Conjugated polymers and organic semiconductors promise great advances in electronics because of the benefits they offer over silicon, including being cheaper with less demanding manufacturing requirements and allowing for larger, more flexible, and more robust materials that are more re
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Nanocellular Foaming of Ultra High Molecular Weight Polyethylene using Ultrasound

Introduction Ultra high molecular weight polyethylene (UHMWPE) is a thermoplastic consisting of molecules of incredibly long chains with molecular weights of several million. It has the highest impact strength of any thermoplastic, has a high resistance to corrosion, moisture, and abrasion, and has
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Method of Detecting, Characterizing, and Quantifying Bulk, Light-Element Materials Using High-Energy, Penetrating X-Rays

Introduction X-rays have long been used in the characterization of a wide variety of materials. However, conventional techniques for dealing with light-element (or low-Z) materials, such as those containing nitrogen and carbon, are too low in energy to penetrate significant distances into enclosing
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Electrochemical Method of Reducing Scale on or in Metal Pipes

Nearly all industries rely on hard water transport through pipelines for process water or heat exchange. In most cases the dissolved salts in the water deposit gradually on the pipe walls, restricting fluid flow and increasing pumping cost. Sometimes these deposits become so large that the pipelines
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Novel Adsorbent Systems for Water Purification Using Metal Oxide Bound to Substrate and Heated Metal Oxide Particles

Introduction There is an ever increasing need for potable water. Improvements in conventional purification technologies allow for savings in both time and money and ensure that clean water is available in areas that need it. Technology Description Professor Benjamin at the University of Washington h
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Novel Adsorbent Systems for Water Purification Using Metal Oxide Bound to Substrate and Heated Metal Oxide Particles

Introduction There is an ever increasing need for potable water. Improvements in conventional purification technologies allow for savings in both time and money and ensure that clean water is available in areas that need it. Technology Description Professor Benjamin at the University of Washington h
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A Polymer-Based Integrated Optical Image Acquisition and Display System

Introduction Imaging devices are used in a variety of roles from medical imaging to barcode reading, and as these devices get smaller, their number of potential applications only increases. Endoscopes, for example, allow for real-time imaging inside the body; conventional versions, however, are limi
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Tissue-Engineered Urinary Bladder Using Autologous Cells

Introduction There is a variety of reasons that a person’s bladder may fail or require removal, including bladder acontractility, cancer, and cystitis. Unfortunately, conventional artificial bladders tend to suffer from critical complications, such as inadequate performance, infection, and adverse h
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Micro-Fabricated Thermal Conductivity Sensor for Biomaterials

Introduction Advances in microscale technology are constantly opening doors to new and exciting applications. Of special interest, novel microscale biosensors and other diagnostic devices promise to revolutionize patient care and biomedical research with point-of-care devices, personalized medicine,
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Programmable Ultrasound Back-End System Using Multi-Core Processor

Introduction Ultrasonography is a noninvasive medical imaging technique, which utilizes ultrasonic waves to visualize soft tissue within the body, and advances in this technology have led to various therapies, including those that utilize high-intensity focused ultrasound (HIFU) capable of rapidly
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Thermal Responsive Iron Oxide Magnetic Nanoparticles

Introduction Stimuli-responsive materials and molecules have numerous possible applications in the biomedical/pharmaceutical field, as well as in biotechnology and the related industries. Smart conjugates, smart surfaces, smart polymeric micelles and smart hydrogels have all been studied for a varie
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A flexible polymer based smart skin

Introduction For some applications, it is essential to obtain the real time 2-D profiling of certain physical parameters such as temperature, force, pressure, and shear stress on a 3-D object. If the surface of the object is flat, one can use a monolithic MEMS device with large amounts of sensors. H
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Extrusion of Microcellular Foams and Foam Composites

Introduction Conventional extrusion of microcellular foams using supercritical carbon dioxide as a blowing agent needs expensive equipment or specialized modification in order to operate. High pressure and high temperature seals are required on the extruder barrel at the injection for the supercriti
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Nanoimprint Lithography of Organic Functional Materials

Introduction Organic functional materials offer advantages relative to their inorganic analogs including mechanical flexibility and inexpensive fabrication. Similarly, nanoimprint lithography (NIL) has made much progress as an alternative to conventional photolithography that can provide the same p
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A Novel Means of Measuring Mechanical Shear/Pressure Stress using Flexible Polymeric Sensor

Introduction Diabetes is a significant national health care priority and foot complications are one of the more serious considerations. More than 60,000 amputations of the lower extremities are performed every year due to complications arising from diabetes mellitus. Studies have shown that foot ulc
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Polymer based bendloss waveguide sensor for shear and pressure measurement

Introduction Lower limb complications associated with diabetes include the development of plantar ulcers that can lead to infection and subsequent amputation. Several authors have postulated that shear stress is an important component of ulcer development. While it is known from force plate analyses
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Design of Surface Plasmon Biosensor Based on Self-Referencing and Digital Window System

Introduction Surface Plasmon resonance (SPR) has attracted strong attention as a biosensor in the past two decades because it can provide label-free, real-time detection with high sensitivity. Technology description Researchers at the UW have developed an SPR biosensor with increased accurate refere
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Novel Methods of Creating a True Smart Structure for Stress Monitoring and Active Mechanical Support on Footwear

Introduction Investigation of strain sensing has been an active research area for the past 60 years and has the potential to affect a large number of industries and disciplines. The characteristics of all strain sensors depend, to some degree, on the properties of the deformable contact materials. E
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Conductive Composite Polymer and Its Dielectric Polymer Actuator Application

Introduction Elastomers loaded with electrically conductive powders are commonly used in gaskets for EMI shielding applications in electronic devices such as computers, telecommunication equipment and medical devices. It is a challenge to provide the shielding while meeting application-specific elas
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Larger Area Pressure and Shear Measurement Using Optical Time Domain Reflectometer (OTDR)

Introduction Lower limb complications associated with diabetes include the development of plantar ulcers that can lead to infection and subsequent amputation. Several authors have postulated that shear stress is an important component of ulcer development. While it is known from force plate analyses
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System and Method for Increasing the Efficiency of a Solar Heating System

A modified evacuated tube solar collector is used to improve the performance of refrigerant based heat pumps. During cooler weather, when the heat pump does not draw sufficient heat from the air to heat effectively, the solar collector provides additional heat to the refrigerant boosting the heat pu
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Shockwave Reactor

Introduction Ethylene is a commercially important chemical with many applications, and it is especially important as a building block for other, more complex molecules. It is typically made by cracking various larger hydrocarbons using pyrolysis. The hydrocarbon feedstock for these reactions varies
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Directional Sensitive Shear/Pressure Using Fiber-Optic or Dielectric Waveguide Polarimetric Sensor

Introduction Lower limb complications associated with diabetes include the development of plantar ulcers that can lead to infection and subsequent amputation. Several authors have postulated that shear stress is an important component of ulcer development. While it is known from force plate analyses
...

A New Protocol of Diels-Alder Lattice Hardening for Highly Efficient Electro-optic Materials Showing Outstanding Temporal Stability over 200 Degrees C

Introduction Organic electro-optic (EO) materials have attracted much interest in the past two decades because of their extensive potential applications in various fields, ranging from waveguides, switches, emitters, and detectors. Though EO materials have a huge potential in Photonics and Electroni
...

Quantitative Inversion of Scanning Capacitance Microprobe (SCM)

With the shrinkage of semiconductor devices to the sub-micron level, a great need exists for direct, quantitative, two dimensional dopant profile measurements on a nanometer scale. Direct measurement of 2-dimensional dopant profile provides a means for improving very large scale integrated process a
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A Three-Dimensional Distributed Sensor using an integrated Optical Waveguide Array

Introduction A flexible shear and pressure sensor array has been developed by researchers at the University of Washington. The sensors are fiber optic-based, and are imbedded in a thin polymer sheet to allow their use in a wide range of pressure & shear sensing applications. Technology description A
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Tractal Erectile Device

Male Erectile Dysfunction (ED) is a condition that affects many men and can have a negative physical and psychological impact on their lives. Stimulation of the penis may be difficult for men suffering from ED, and although attempts have been made to treat ED, those attempts have failed to provide a
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Sectional Folding Up Garage Door

SECTIONAL FOLDING UP GARAGE DOOR US PATENT 8327908 This is a new, patented automatic sectional garage door. The door opening is going up, where it folds up like an accordion, saving considerable space inside promise and reducing the overall design. The working prototype is already running for
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Composition of the reconstitution medium for protein and peptide formulations

Pharmaceutical scientists at the University at Buffalo have developed a rational strategy to design compositions for the reconstitution of freeze-dried protein/peptide formulations. These compositions confer stability to otherwise unstable protein p roducts such as replacement therapies (i.e. factor
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Automatic Phase Calibration of Two-Dimensional Resonant Scanners

Introduction Mechanically resonant scanners are widely used in optical or near-field imaging. The scanner can trace out imaging beam paths in two-dimensional space in response to a drive waveform near the scanner’s mechanical resonant frequency. The mechanical response will not in general be in phas
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Dynamic Change of Focus for True 3-D, Scanned Retinal Displays

Introduction Generating true 3-D computer displays will enable the creation of more realistic and informative images, allowing improved functionality when relying on visual display data. Technology description Researchers at the UW have developed the use of optical elements to dynamically adjust the
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Design and Fabrication of Optical Probes that use Photo- Chemical Neural Stimulation or Inhibition

Introduction Stimulation of neural tissue is typically done with electrodes inserted into or in close proximity to the neurons. Excitation or inhibition of a neural pathway is accomplished by electrically stimulating the neighboring neurons. The lack of longterm functionality of these electrodes is
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Mechanical Transmission for Electric Motors

Most systems use a clutch to change gear - Our system uses brake. The system is unique propulsion system suitable for electric motors, the system includes an innovative combination of an electric motor with a mechanical transmission with two speeds or more in order to increase efficiency and allow
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Active Contact Lens

Introduction The interstitial fluid in the eye over the cornea is in indirect contact with blood serum via capillaries in the eye and is a good target for biomarkers that signal certain health conditions. If sensors and data transmitters could be implanted in a contact lens, the health of the user c
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Use of Adhesion Molecules as Shear-Induced Nanoscale Binding Switches

Introduction Methods, compositions, and devices for using shear-dependent binding switches in a variety of applications would be extremely useful in biomedical and other fields. Applications for this technology include the following: 1) as a non-invasive probe for force fields; 2) to control the agg
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Delivery of PEGylated Drugs from Bioadhesive Formulations

Introduction While significant advances have been made in the field of PEGylated drug delivery, there is still a need for novel and improved PEGylated drug delivery formulations, particularly those that are useful in the area of sustained drug delivery. Technology description Researchers at the Univ
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Flexible Fiber-Optic Scanning Multiphoton or Harmonic Miniature Imaging Probe

Introduction Endoscopes are increasingly involved in performing common surgical procedures and in diagnosing cancer and other medical conditions. New technologies can demonstrate significant cost savings by moving these procedures from an inpatient to an outpatient setting. Technology description Re
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Clutter Rejection Filters for Doppler Optical Coherence Tomography

Introduction Doppler optical coherence tomography (DOCT) is a recently developed technology that can image blood flow with high special and temporal resolution. Technology description Researchers at the UW have developed techniques to improve the sensitivity of DOCT for real-time flow imaging by usi
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Precision coating of macromolecules on Surfaces

Introduction Production of chemically modified surfaces by ion deposition allows for unique chemistries on those surfaces, providing functionalities that are critical to medical devices such as stents and vascular grafts. Sophisticated materials are now required for complex medical applications such
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Fluid flow assisted dielectrophoretic alignment and sorting of dielectrophoretic alignment and sorting of

Introduction The accurate and precise sorting and deposition of nano/bio materials within a nano- or micro-environment is critical for the functionality of devices such as biochips. Fluid flow in a microchannel is one method of controlling long-range transport and electric fields may be employed to
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Sun block applicator

Skin cancer is the most common form of cancer in the United States. Here are the American Cancer Society’s estimates for melanoma in the United States for 2014: About 76,100 new melanomas will be diagnosed (about 43,890 in men and 32,210 in women). About 9,710 people are expected to die of melano
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Intraocular Drug Delivery System

Introduction 10 million intraocular lenses are implanted each year worldwide in which infection is a major concern. In order to prevent serious infections that can lead to blindness, antibiotic drops are prescribed to be administered after surgery by the patient. Antibiotics are applied to the eye u
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New biocompatible and biodegradable polymers

Introduction Porous biodegradable scaffolds are ideal materials on which, new tissue may be grown. These new tissues are used as graft material to replace damaged tissue removed during surgery. These polymers may also be used in drug delivery systems and for medical device coating. Technology descri
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Automated laboratory system and analytical module

Our invention: Fast Lab Technology is a cornerstone in preventive and lower cost health care of USA Government program: http://www.codebuildingblocks.com/Michael/FastSpin Our technology intends to decrease time and cost of routine and esoteric tests and comprises some new engineering methods and
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Process for making reinforcing elastomer-clay nanocomposites

A process for producing a natural rubber nanocomposite containing exfoliated organically modified montmorillonite and maleic anhydride grafted elastomer in a dispersion of natural rubber and reinforcing filler/inert filler wherein the cured nanocomposite has improved mechanical properties compared t
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PEO Coated IOL

Introduction Intraocular lenses (IOL) are well established in the area of ophthalmology, and are often used to replace a natural lens affected by cataracts or to compensate for refractive errors. IOL implantation is considered to be surgically advantageous, particularly in the treatment of cataracts
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BioFuel-based Penetrating Oil - Petroleum Free

BioFuel-based Penetrating Oil - Petroleum Free

1. A kerosene replacement, consisting of a biodiesel and ethanol mixture, wherein said mixture is between 70 and 90 percent ethyl-ester fatty acid derived biodiesel by volume, and between 10 and 30 percent ethanol by volume, and is suitable for use as penetrating oil. 2. A composition as in clai
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“Artificial nose” based on surface plasmon resonance sensor derivatized with specific biofilms

Introduction Surface plasmon resonance (SPR) sensors can be used for the detection of target chemical, biochemical, and biological analyte binding in a very specific and sensitive manner. One of the biggest limitations to this technology is the speed with which detection can take place. Slow rates o
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Water Flow and Temperature Controller for a Bathrub Faucet

SHOWER, BATHTUB, OR SPA MONITOR. I.E. "THE SHOWER MONITOR" A temperature and flow controller for a bath tub or shower is disclosed. The device includes a panel that replaces or surrounds the standard bath tub water valves. Within the panel is a control assembly in communication with temperature s
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Engine Block Component Brace

Valley Girdle™, Valley Girdle Pro™, United States Patent for Engine Block Component Brace : Patent # 7,258,094 One or more component braces may be installed into the upper valley of a V-styled engine block to provide resistance to deformation of the block when used in an operating motor. The comp
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