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Electrochromic-Photovoltaic Film for Light-Sensitive Control of Optical Transmittance

A variable transmittance optical component includes an electrochromic material and a photovoltaic device-type thin film solar cell deposited in a tandem type, monolithic single coating over the component. A bleed resistor of a predetermined value is connected in series across the electrochromic mate
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Electrochromic Projection and Writing Device

A display and projection apparatus includes an electrochromic material and a photoconductive material deposited in tandem used in conjunction with a light filtering means for filtering light transmitted through the electrochromic material. When an electric field is applied across the electrochromic
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High Rate Chemical Vapor Deposition of Carbon Films Using Fluorinated Gases

A high rate, low-temperature deposition of amorphous carbon films is produced by PE-CVD in the presence of a fluorinated or other halide gas. The deposition can be performed at less than 100.degree. C., including ambient room temperature, with a radio frequency plasma assisted chemical vapor deposit
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Fiber Optic Device for Sensing the Presence of Gas

A fiber-optic device for sensing the presence of a gas in an environment is provided. The device comprises a light source for directing a light beam to a layer system having a first surface and a second surface opposite the first surface. The first surface is exposable to the light beam and the seco
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Controlled Catalytic and Thermal Sequential Pyrolysis and Hydrolysis of Mixed Polymer Waste Streams to Sequentially Recover Monomers or Other High Value Products

A process of using fast pyrolysis in a carrier gas to convert a plastic waste feedstream having a mixed polymeric composition in a manner such that pyrolysis of a given polymer to its high value monomeric constituent occurs prior to pyrolysis of other plastic components therein comprising: selecting
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Co-registration of PET and Transrectal Ultrasounds (TRUS) Images for Improved Prostate Imaging and Biopsy

APPLICATIONS OF TECHNOLOGY: Detects prostate cancer using accurately co-registered positron emission tomography (PET) and transrectal ultrasound (TRUS) images Guides prostate biopsy sampling Monitors response to treatment and detects local recurrence ADVANTAGES: Provides high-resolution
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Diagnostic MRI Skin Map Database

IB-2390 APPLICATIONS OF TECHNOLOGY: Using MRI data to develop a database that systematically characterizes skin properties Developing a skin map for a patient and comparing it to the database to determine the best treatment Using a patient’s MRI skin map data to determine the settings o
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A Diagnostic Test to Personalize Therapy Using Platinum-based Anticancer Drugs

JIB-2441 APPLICATIONS OF TECHNOLOGY: Personalize therapy using platinum-based anticancer drugs ADVANTAGES: Can be used to tailor cancer treatments to individual patients Reduces unnecessary cancer treatments and the associated side effects Enables new therapeutic strategies for canc
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Electrostatic-based DNA Microarray Technique

JIB-2397 Press Release, Berkeley Lab, June 30, 2008 The dream of personalized medicine — in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profile — may be on the verge of being expanded beyond the wealthiest of nations with state-of-the-art clini
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Method for Identifying New Breast Cancer Stem Cells and Targeted Therapies

JIB-2395 APPLICATIONS OF TECHNOLOGY: Development of new breast cancer therapies and diagnostic assays Researching cancer progression and remission ADVANTAGES: Specifically isolates human mammary stem and progenitor cell candidates from primary mammary tissue May identify new mammary stem
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Non-Transgenic Cell Lines for Identifying Target Premalignant Genes

IB-2023 Berkeley Lab's S3 cell lines display partial loss of differentiation in 3DirBM Cultures. Human breast epithelial cell lines were derived from a patient with fibrocystic breast disease. The epithelial tissue gave rise to non-tumorigenic S1 cells, from which more aggressive S2 cell
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SATB1: a Fundamental Prognostic Marker and Therpeutic Target for Metastatic Breast Cancer

IB-2186 Published in Nature, March 2008. See link below. APPLICATIONS OF TECHNOLOGY: Screening for metastatic-prone breast cancers Using SATB1-specific inhibitors to treat breast cancer Designing assays to detect SATB1 expression in aggressive breast cancer cells Creating therapies
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A Cell Injection System Using Carbon Nanotubes

IB-2323, IB-2333 APPLICATIONS OF TECHNOLOGY: Transfection of foreign molecular-scale cargoes into cells (e.g. DNA, RNA, polymers, dendrimers, nanoparticles, etc.) Insertion of probes into cells to observe physical and biochemical interactions. (e.g. quantum dots-probes) ADVANTAGES: Unlike
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Biological Production of Polymer Monomers

EJIB-2541 APPLICATIONS OF TECHNOLOGY: Producing a wide variety dicarboxylic acids for the manufacture of commercial polymers, e.g. polyesters, polyamides, polyurethanes ADVANTAGES: Starting material is renewable, cellulosic or other biomass instead of petroleum Enzymes can be modified to
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Compact Vacuum Insulation

An ultra-thin compact vacuum insulation panel is comprised of two hard, but bendable metal wall sheets closely spaced apart from each other and welded around the edges to enclose a vacuum chamber. Glass or ceramic spacers hold the wall sheets apart. The spacers can be discrete spherical beads or mon
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Increasing Jet Entrainment, Mixing and Spreading

A free jet of air is disturbed at a frequency that substantially matches natural turbulences in the free jet to increase the entrainment, mixing, and spreading of air by the free jet, for example in a room or other enclosure. The disturbances are created by pulsing the flow of air that creates the f
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Low Thermal Resistance Power Module Assembly

A power module assembly with low thermal resistance and enhanced heat dissipation to a cooling medium. The assembly includes a heat sink or spreader plate with passageways or openings for coolant that extend through the plate from a lower surface to an upper surface. A circuit substrate is provided
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Material-Controlled Dynamic Vacuum Insulation

A compact vacuum insulation panel comprising a chamber enclosed by two sheets of metal, glass-like spaces disposed in the chamber between the sidewalls, and a high-grade vacuum in the chamber includes apparatus and methods for enabling and disabling, or turning "on" and "off" the thermal insulating
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Radiation-Controlled Dynamic Vacuum Insulation

A compact vacuum insulation panel comprising a chamber enclosed by two sheets of metal, glass-like spaces disposed in the chamber between the sidewalls, and a high-grade vacuum in the chamber that includes apparatus and methods for enabling and disabling, or turning "on" and "off" the thermal insula
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Method and Apparatus for High-Efficiency Direct Contact Condensation

A direct contact condenser having a downward vapor flow chamber and an upward vapor flow chamber, wherein each of the vapor flow chambers includes a plurality of cooling liquid supplying pipes and a vapor-liquid contact medium disposed thereunder to facilitate contact and direct heat exchange betwee
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Hydrogen Permeable Protective Coating for a Catalytic Surface

Nanostructures and methods for production thereof by phase separation during metal organic vapor-phase epitaxy (MOVPE). An embodiment of one of the methods may comprise providing a growth surface in a reaction chamber and introducing a first mixture of precursor materials into the reaction chamber t
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Hydrogen Producting Using Hydrogenase-Containing Oxygenic Photosynthetic Organisms

This invention relates to photosynthetic hydrogen production and specifically to a biophotolysis process, which can be cycled, for the temporal separation of oxygen evolution and hydrogen production in algae.
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Method and apparatus for determining diffusible hydrogen concentrations

A measuring apparatus and method for use in measuring diffusible hydrogen concentrations in materials, structures, and other objects. In an embodiment of the invention for use in welding applications, the measuring apparatus (10) includes a sensor assembly (20) that, with an included sealing member
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Method and Apparatus for Rapid Biohydrogen Phenotypic Screening of Microorganisms Using a Chemochromic Sensor

The invention provides an assay system for identifying a hydrogen-gas-producing organism, including a sensor film having a first layer comprising a transition metal oxide or oxysalt and a second layer comprising hydrogen-dissociative catalyst metal, the first and second layers having an inner and an
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Process for Selection of Oxygen-tolerant Algal Mutants that Produce H.sub.2

A process for selection of oxygen-tolerant, H.sub.2 -producing algal mutant cells comprising:(a) growing algal cells photoautotrophically under fluorescent light to mid log phase;(b) inducing algal cells grown photoautrophically under fluorescent light to mid log phase in step (a) anaerobically by (
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System for Rapid Biohydrogen Phenotypic Screening of Microorganisms Using a Chemochromic Sensor

Provided is a system for identifying a hydrogen gas producing organism. The system includes a sensor film having a first layer comprising a transition metal oxide or oxysalt and a second layer comprising a hydrogen-dissociative catalyst metal, the first and second layers having an inner and an outer
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Airfoils for Wind Turbine

Airfoils for the tip and mid-span regions of a wind turbine blade have upper surface and lower surface shapes and contours between a leading edge and a trailing edge that minimize roughness effects of the airfoil and provide maximum lift coefficients that are largely insensitive to roughness effects
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Airfoils for Wind Turbine

Airfoils for the blade of a wind turbine wherein each airfoil is characterized by a thickness in a range from 16%-24% and a maximum lift coefficient designed to be largely insensitive to roughness effects. The airfoils include a family of airfoils for a blade 15 to 25 meters in length, a family of a
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Cooling-tower Fan Airfoils

A family of airfoils for a blade of a cooling-tower fan, is provided wherein the blade has a root region and a tip region, the family of airfoils comprises an airfoil (30) in the root region of the blade having a Reynolds number of 500,000, and an airfoil (20) in the tip region of the blade having a
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Root Region Airfoil for Wind Turbine

A thick airfoil for the root region of the blade of a wind turbine. The airfoil has a thickness in a range from 24%-26% and a Reynolds number in a range from 1,000,000 to 1,800,000. The airfoil has a maximum lift coefficient of 1.4-1.6 that has minimum sensitivity to roughness effects.
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Variable-Speed Wind Power System with Improved Energy Capture via Multilevel Conversion

A system and method for efficiently capturing electrical energy from a variable-speed generator are disclosed. The system includes a matrix converter using full-bridge, multilevel switch cells, in which semiconductor devices are clamped to a known constant DC voltage of a capacitor. The multilevel m
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Variable Speed Wind Turbine Generator with Zero Sequence Filter

A variable speed wind turbine generator system to convert mechanical power into electrical power or energy and to recover the electrical power or energy in the form of three phase alternating current and return the power or energy to a utility or other load with single phase sinusoidal waveform at s
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Zymomonas Pentose-Sugar Fermenting Strains and Uses Thereof

Disclosed in the present invention is a Zymomonas integrant and derivatives of these integrants that posess the ability to ferment pentose into ethanol. The genetic sequences encoding for the pentose-fermenting enzymes are integrated into the Zymomonas in a two-integration event of homologous recomb
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Use of a Region of the Visible and Near Infrared Spectrum to Predict Mechanical Properties of Wet Wood and Standing Trees

In a method for determining the dry mechanical strength for a green wood, the improvement comprising: (a) illuminating a surface of the wood to be determined with a reduced range of wavelengths in the VIS-NIR spectra 400 to 1150 nm, said wood having a green moisture content; (b) analyzing the surfac
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Au-NP: High-Resolution Biomarkers as Indicators of Nanotoxicity

IB-2419 APPLICATIONS OF TECHNOLOGY: • Determining the toxicity and biological effects of nanoparticles • Assessing health, occupational, and environmental risks of nanomaterials • Establishing safety standards for the use of nanomaterials in biomedical and clinical applications • Fine-tun
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Bioremediation System for Separating Nanoparticle Waste

IB-2374 APPLICATIONS OF TECHNOLOGY: • Removes soluble nanoparticles from water by aggregation and precipitation in solution • Can be used to clean up metal, metal oxide, and semiconductor nanoparticles • Inhibits growth of organisms in wastewater • Provides a means for assessing the toxicity
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Cost-Effective, Laser-Assisted in Situ Nanostructure Fabrication and Processing

JIB-2121 APPLICATIONS OF TECHNOLOGY: Nanoscale fabrication and manufacturing of: • Medical micro- and nano-devices including components for implants • Materials and structures for microelectronics and optoelectronics • Contacts, circuit lines, interconnects, and integrated circuits for semic
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Graphene Membranes for Nanometer-scale Lithography and Single Atom Resolution TEM Imaging

IB-2501, 2502 APPLICATIONS OF TECHNOLOGY: • Using electron-beam induced deposition (EBID) on graphene membranes to create nano-scale doping patterns for electronic circuits lithography etch masks diffraction gratings (for monochromators, spectrometers, wavelength division multiplexing devices,
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Method and Apparatus for Adjustably Inducing Biaxial Strain

IB-1910 APPLICATIONS OF TECHNOLOGY: • Understanding the dynamic changes in the microstructure of thin films as a function of biaxial strain • Inducing biaxial strain in thin films for failure analysis • Improving the reliability and performance of devices such as microactuators, biological mi
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Fluorine Separation and Generation Device

IB-1847 APPLICATIONS: • Point of use fluorine generation, separation, and recycling ADVANTAGES: • Compact solid state system • Extremely high purity fluorine separation, allowing the gas to be recycled on site • Decreases fluorine waste and reduces the amount of fluorine purchased and tr
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Accurate Identification, Imaging and Monitoring of Fluid-Saturated Underground Reservoirs

IB-1663 APPLICATIONS OF TECHNOLOGY: • Search for and contouring of gas and oil deposits • Underground water reservoir imaging • Estimation of the size and shape of contamination zones • Monitoring of underground liquid and gas storage • CO2 sequestration problem ADVANTAGES: • Allows char
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Co-registration of PET and Transrectal Ultrasounds (TRUS) Images for Improved Prostate Imaging and Biopsy

IB-2420 Dual PET-TRUS imaging co-registers positron emission tomography and transrectal ultrasound images taken during the same patient exam. The simulated “merged PET-TRUS image” (central image), helping to pinpoint any cancer present, will be used to guide diagnosis and potential treatments, as
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Dedicated Test Surface for Calibration of High-Performance Optical Systems

IB-2499 APPLICATIONS OF TECHNOLOGY: • A prototype binary pseudo-random grating test surface is etched into a silicon substrate using a conventional lithographical process. • Testing of surface profilometers • Calibrates modulation transfer function (MTF) of microscopes • Direct 2D calibration
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High Efficiency Micro-Scale Light-Concentrating Arrays for Digital Imaging

IB-2279 APPLICATIONS OF TECHNOLOGY: • Digital imaging • Digital cameras, image scanners, and pixelated detectors • Applicable to visible, ultraviolet and infrared cameras ADVANTAGES: • Maximum efficiency of light collection in pixels on the micron scale • Ease and simplicity of manufactu
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Heat Shrinkable Sheathing

IB-2475 APPLICATIONS OF TECHNOLOGY: Strapping and bundling objects together tightly ADVANTAGES: • Enabling of multiple assemblies to be fitted and then tightened as a group with one application of heat • Fitting shrinkable tubing to endless or looped structures without disassembly of struc
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Optical Sedimentation Recorder (OSR) for Tracking the Ocean's Carbon Flux

IB-2196 APPLICATIONS OF TECHNOLOGY: In appearance and size similar to a compressed gas cylinder, the OSR is a multi-platform instrument that: • Precisely measures the ocean’s hourly variations of sedimentation of particulate inorganic and organic carbon material for seasons to years • Comb
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PhyloChip: DNA Microarray for Rapid Profiling of Microbial Populations

APPLICATIONS OF TECHNOLOGY: • Monitoring airborne bacteria for bioterrorism surveillance • Berkeley Lab’s DNA Microarray for Rapid Profiling of Microbial Populations, also called PhyloChip. • Tracking microbial changes in the atmosphere due to climate change • Detecting harmful and beneficial
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Bore II - Advanced Wellbore Technology Characterizes Groundwater Flow and Contamination

APPLICATION OF TECHNOLOGY: • Contaminated site and remedial investigation studies • Municipal water supply studies • EPA wellhead protection area and groundwater management/protection studies • Geotechnical pretesting for construction and design ADVANTAGES: • Identifies water-bearing zones a
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Gas Exploration Software for Reducing Uncertainty in Gas Concentration Estimates

APPLICATIONS OF TECHNOLOGY: Improve estimation of reservoir parameters and quantify uncertainty in the estimation when exploring for gas and oil deposits using geophysical data ADVANTAGES: • Provides extensive uncertainty information to reduce the chances of drilling in uneconomical locations
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Tunable Thermal Link

APPLICATIONS OF TECHNOLOGY: - Electronic and thermal circuit design and operation - Solar energy collection - Heat pumps and internal combustion engines - Hybrid biological/inorganic systems - Phononic information processing - Energy-efficient buildings and appliances, such as refrigerators AD
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Boron Nitride Nanotubes with Modified Surfaces

APPLICATIONS OF TECHNOLOGY: - Mechanical reinforcements and composites, e.g. cell phone cases, structural elements of aircraft - Batteries, supercapacitors - Fuel cell components - Transistors, biosensors - Field emission sources - Electronic circuits - Scaffolds for novel chemistries - Deep ultr
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Employee-Identification-Triggered First Aid Box

APPLICATIONS OF TECHNOLOGY: - Ensure ready access to and inventory control of emergency response supplies - Ensure communication to allow for proper response and follow-up of emergency incidents - Replenish emergency supplies to prepare for next response ADVANTAGES: - Detects and identifies emp
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LABELIT – Software for Macromolecular Diffraction Data Processing

APPLICATIONS OF TECHNOLOGY: - Automatically index X-ray diffraction images - Quickly summarize the diffraction quality - Determine Laue symmetry from a partial dataset ADVANTAGES: - Makes visual inspection of images unnecessary - Better algorithms for spot picking - More robust indexing procedu
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Nanotube Radio for Communications and Medical Applications

APPLICATIONS OF TECHNOLOGY: - All-in-one radio receiver for cell phones/wireless networks/GPS and other electronic devices - Radio controlled devices that can exist inside the body, e.g. used as drug release triggers, diagnostic instrumentation, interfacing with muscle or brain function - Ultra sma
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Flooring Device for Postioning on Joists

A FLOOR APPARATUS FOR FORMING A FLOOR OVER EXPOSED JOISTS IN AN ATTIC,THE APPARATUS COMPRISING: A PLURALITY OF SUBSTANTIALLY RIGID PANELS ARRANGED ADJACENT TO EACH OTHER IN A SERIES, EACH OF THE PANELS HAVING A TOP SIDE, A PAIR OF RELATIVELY LONGER AND OPPOSITE SIDE EDGES: AND CONNECTING EACH PANEL
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Device and method of positionally accurate implantation of individual particles in a substrate surface

A device and a method for positionally accurate implantation of individual particles in a substrate surface (1a) are described. A diaphragm for a particle beam to be directed onto the substrate surface (1a) and a detector provided thereon in the form of a p-n junction for determining a secondary ele
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Rough Silicon Nanowires for Heat Harvesting and Cooling Applications

APPLICATIONS OF TECHNOLOGY: - Heat harvesting - Electricity for internal automobile use, i.e. heating, windows - Conversion of automotive exhaust into supplemental power for hydrogen fuel cell-powered cars - Power jackets using heat from human body to power electronic devices - Thermoelectric coo
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New Multimodal Probes Compatible with Flourescence and MRI

APPLICATIONS OF TECHNOLOGY: - Effective as multimodal probes for: - Imaging - Targeting specific cells or tissue - Therapeutics delivery and imaging in vivo or in vitro - Detects locality and size of diseased cells by MRI, PET, ESR, or deep tissue NIR with greater sensitivity than possible with ex
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Termite Microbial Enzymes for Energy Efficient Biofuel Production

APPLICATIONS OF TECHNOLOGY: Converting plant lignocellulosic biomass to simple sugars for fermentation into biofuels, and hydrogen. ADVANTAGES: - Promises to be more energy and chemically efficient than the fungal enzymes currently in use - Combinations of the enzymes could be optimized for a p
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Low Power, High Energy Gamma Ray Detector Calibration Device

APPLICATIONS OF TECHNOLOGY: - Calibrating the energy output and efficiency of high resolution HPGe detectors used in environmental monitoring and physics research - Calibrating large gamma ray detectors being developed for homeland security cargo screening and neutrino detectors - Educating physici
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Focused Electron and Ion Beam Systems

ABSTRACT: An electron beam system is based on a plasma generator in a plasma ion source with an accelerator column. The electrons are extracted from a plasma cathode in a plasma ion source, e.g. a multicusp plasma ion source. The beam can be scanned in both the x and y directions, and the system ca
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Sub-5 Nanosecond Neutron Generator for Detection of Explosives

APPLICATIONS OF TECHNOLOGY: - Screening of luggage and cargo for explosives and fissile material - Gamma ray and neutron detection ADVANTAGES: - Produces short 5 nanosecond neutron pulses - Minimizes alignment problems - Reduces RF input power requirement - Removes spurious background particle
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Composites with Graded Microstructures for Orthopedic Implants and Bone Tissue Engineering

An inorganic scaffold with a strong, dense core and graded porosity is infiltrated with different polymers to provide a gradient in solubility. Porosity is greatest at the surface, promoting cell attachment and formation of new tissue. APPLICATIONS OF TECHNOLOGY: - Orthopedic implants with
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Graded Bioactive Glass and Glass/Ceramic Coatings for Metal Bone Implants

Bioactive glass can be tuned to the same thermal expansion coefficient as the titanium (Ti) alloy it coats, avoiding the generation of thermal stresses. Processing at 800°C results in a 100-nm-thick adhesive interface layer between the coating and the Ti alloy. - Bone implants - Dental imp
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Injectible Hydrogel-Based Biodegradable Bone Replacement Materials

Microstructure of a FlexBone hydrogel/HA composite (the white dots are HA particles). APPLICATIONS OF TECHNOLOGY: - Bone implants - Dental implants - Injectable bone cements - Drug delivery - Scaffolds for bone tissue engineering ADVANTAGES: - Promotes natural bone growth as it biodegra
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Low Cost, High Efficiency Tandem Silicon Solar Cells

APPLICATIONS OF TECHNOLOGY: Berkeley Lab's solar cell design incorporating the low-resistance tunnel junction. The tunnel junction is between the middle two materials. Inexpensive tandem silicon solar cells ADVANTAGES: - Boosts silicon solar cell efficiency without significant cost increase
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Membrane and Receptors for Highly Selective Gas-Phase Sensing

APPLICATIONS OF TECHNOLOGY: Comparative binding assay data suggests the levels of binding to TNT for the DNT designated receptor are on the order of non-specific interaction, confirming that the designated receptor is indeed selective for the DNT target. The selectivity between TNT and DNT is sign
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Microgels with Acid-Degradable Polymer Backbones for Delivering Bioactive Materials

APPLICATIONS OF TECHNOLOGY: Berkeley Lab synthesis of linear acid-degradable polymers and protein-loaded particles. - Targeted delivery of protein and DNA-based therapeutics - Vaccine delivery - Cancer immunotherapy - Site-specific treatment of inflammation - Anti-sense therapy ADVANTAGES: -
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High Frequency Abacus Nanotube Resonator

APPLICATIONS OF TECHNOLOGY: Filter or amplifier for microwave frequency and RF electronics, e.g. cell phones, personal music devices Mass sensor ADVANTAGES: - Frequencies over 4 GHz - Operates at ambient temperatures and pressures without significant loss of resonance quality - Individually tun
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Thermal Profiling of Nanoscale Circuitry

APPLICATIONS OF TECHNOLOGY: - Thermal management of small devices and systems, whether semiconductor electronics, nanofluidics, or photovoltaics - Design, prototyping and characterization of new circuit models - High-resolution measurement at extreme temperatures ADVANTAGES: - Does not interfer
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High Selectivity Peptides for Cancer Therapy, Screening for Cancer Therapies, and Therapy Sensitization

APPLICATIONS OF TECHNOLOGY: - High-throughput screening for therapeutics that synergize with TIN2 complex disruption - Sensitizing cancer cells to other therapeutic agents - Therapy for multiple types of cancer exhibiting p53-negative cancer cells ADVANTAGES: - Targets a subset of aggressive ca
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Non-Surgical Skin Enhancement Through Rhamm Protein Modulation

This invention is not a product, but an early-stage technology available to qualified companies for licensing or research partnering. Rhamm deletion promotes subcutaneous fat in mice APPLICATIONS OF TECHNOLOGY: - Normalizing skin appearance after reconstructive or cosmetic surgery, i.e. graft
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Electrospray Emitters for Integrating Mass Spectrometry with Microfluidic Devices

APPLICATIONS OF TECHNOLOGY: - Multinozzle electrospray emitters for proteome-on-a-chip - Mass spectroscopy of peptides and biomolecules with a wide range of weights - Process for fabricating complex silicon-based bioanalytical tools ADVANTAGES: - First monolithic interface between mass spec
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Air-stable Nanomaterials for Efficient OLEDs and Solar Cells

Berkeley Lab researchers have developed two approaches for increasing the charge efficiencies of electrodes used to produce flexible organic light emitting diodes (OLEDs) and solar cells. Both approaches will reduce manufacturing and packaging costs. ________________________________________________
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Methods and Proteins for Developing New Classes of Antibiotics

APPLICATIONS OF TECHNOLOGY: - Antibiotics for human and veterinary medicine - Pesticides for crop management - Food preservatives - Genes engineered into probiotic bacteria ADVANTAGES: - Overcomes antibiotic-resistance of bacteria - Isolates new types of antimicrobial proteins that can be used
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Amorphous Silicon Array for Medical Imaging

APPLICATION OF TECHNOLOGY: In medical imaging, this device can provide for real-time electronic imaging in digital radiography (x-rays) and serve as a detector in computerized tomography (CAT scans). One application in medical radiation therapy is related to cancer treatment. Sophisticated techniqu
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Assays Based on the Role of Dystroglycan and Alpha-Dystroglycan Proteolysis in Tumor Cell Growth

PATENT SUMMARY: The present invention relates to methods and compositions for the diagnosis and treatment of cells lacking normal growth arresting characteristics. This characteristic is referred to as "tumorigenicity," which means the properties of a cell normally associated with tumor forming pro
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Biomarker for Cell Senescence

A test developed by Berkeley National Laboratory researchers uses blue stain to detect the presence of senescent cells. The assay top left shows young tissue with no presence of blue; top right is young sunburned tissue, also negative. Older tissue cells, pictured in the bottom four assays, contain
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Partnership to Develop a Furniture-Like Biohazard Control Station

Berkeley Lab is seeking a qualified partner(s) to work with us in the development of a Biohazard Control Station (BCS) which we see as a furniture-like piece of equipment fitting into the modern office setting. A BCS will be employed to safely open potentially contaminated mail at various distributi
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Novel Catalyst Exchanges Deuterium or Tritium into Organic and Organometallic Compounds

APPLICATION OF TECHNOLOGY: Preparing deuterium- or tritium-labeled organic and organometallic compounds for: - Manufacturing pharmaceuticals, chemicals, and agricultural products - Spectroscopic experiments - Research on chemical structure and reaction mechanisms - Analytical tracers ADVAN
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Color and Shape Changing Polymeric Ribbons and Sheets

PATENT APPLICATION ABSTRACT: The present invention provides the design, synthesis and characterization of compositions comprising asymmetric bolaamphiphilic lipids that form extended polymeric ribbons and wide sheets. These compositions may be doped, or interspersed, with various compounds to fine-
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Colorimetric and Fluorescent Sensors for Rapid and Direct Detection of Influenza, E. coli and Other Analytes

APPLICATION OF TECHNOLOGY: - Rapid test kits for influenza and other diseases - Simple detection of E. coli and other bacteria in foods or on surfaces - Drug development and improvement - Detection of DNA hybridization - Detecting pollutants DEMONSTRATED DETECTION: Influenza, E. coli, cholera t
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Comprehensive Prognostic Markers and Therapeutic Targets for Drug-Resistant Breast Cancers

APPLICATIONS OF TECHNOLOGY: Under a microscope, fluorescent markers (right) reveal amplified genes in the chromosomes of a breast tumor’s cells. - Identifying patients with breast cancers that are resistant to conventional chemotherapies and developing new treatment strategies for them - Screeni
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Early Identification of Vulnerable Atherosclerotic Plaques Using in Vivo MIR Spectroscopy and Imaging

APPLICATION OF TECHNOLOGY: - Predicting future recurrence of acute coronary syndromes - In vitro mid-infrared (MIR) spectroscopy imaging of cells influencing atherosclerosis development - In vivo characterization of atherosclerotic plaques - Monitoring the effect of medical treatment on plaques
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Fast Scintillation Detectors Using Direct-Gap Semiconductors

APPLICATION OF TECHNOLOGY: - Detection of ionizing radiation (e.g. x-rays, gamma rays, neutrons) - Nuclear materials detection - Nondestructive materials evaluation - Nuclear medical imaging - Electromagnetic shower counters for high energy physics and astrophysics - Oil well logging ADVANTAGES
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Full Karyotype Analysis for Increasing Pregnancy Rates per IVF Cycle

APPLICATIONS OF TECHNOLOGY: - Screening all 24 chromosomes for numeric chromosome abnormalities during Preimplantation Genetic Diagnosis - Diagnosing disease states requiring cytogenetic analysis - Monitoring the effects of accidental or occupational exposure to environmental hazards ADVANTAGES
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Genes Encoding Telomere-Associated Proteins

APPLICATIONS OF TECHNOLOGY: - Molecular biology research - Medical research ABSTRACT: Telomeres are believed to be critical regulators of the genome, and telomere stability important for preventing cancer and ageing. Regulation of telomere length is believed to be controlled by multiple telomere
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High Quantum Efficiency Charge-Coupled Device

APPLICATIONS OF TECHNOLOGY: Low-level light imaging (Astronomical research, Raman Spectroscopy) ADVANTAGES: - Back illuminated - High near-IR quantum efficiency without fringing - Excellent broadband wavelength response - Fully depleted for improved spatial resolution - Simplified fabrication -
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Low-resistivity Photon-transparent Window Attached to Photo-sensitive Silicon Detector

AVAILABLE TECHNOLOGIES Low-resistivity Photon-transparent Window Attached to Photo-sensitive Silicon Detector APPLICATION OF TECHNOLOGY: - Medical Imaging - Other Digital Scanning technologies ADVANTAGES: - Inexpensive and efficient - High quantum efficiency without thinning - Backlighting
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Method for Charging a Hydrogen Getter

A method for charging a sample of either a permanent or reversible getter material with a high concentration of hydrogen while maintaining a base pressure below 10.sup.-4 torr at room temperature involves placing the sample of hydrogen getter material in a chamber, activating the sample of hydrogen
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Method for Improving the Durability of Ion Insertion Materials

The invention provides a method of protecting an ion insertion material from the degradative effects of a liquid or gel-type electrolyte material by disposing a protective, solid ion conducting, electrically insulating, layer between the ion insertion layer and the liquid or gel-type electrolyte mat
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Method and Apparatus for Rapid Biohydrogen Phenotypic Screening of Microorganisms Using a Chemochromic Sensor

The invention provides an assay system for identifying a hydrogen-gas-producing organism, including a sensor film having a first layer comprising a transition metal oxide or oxysalt and a second layer comprising hydrogen-dissociative catalyst metal, the first and second layers having an inner and an
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Method of High-Purity Silane Preparation

A process for the preparation of high purity silane, suitable for forming thin layer silicon structures in various semiconductor devices and high purity poly- and single crystal silicon for a variety of applications, is provided. Synthesis of high-purity silane starts with a temperature assisted rea
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Microwave Impregnation of Porous Materials with Thermal Energy Storage Materials

A method for impregnating a porous, non-metallic construction material with a solid phase-change material is described. The phase-change material in finely divided form is spread onto the surface of the porous material, after which the porous material is exposed to microwave energy for a time suffic
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Thermostable Purified Endoglucanase II from Acidothermus Cellulolyticus ATTC

A purified low molecular weight endoglucanase II from Acidothermus cellulolyticus (ATCC 43068) is disclosed. The endoglucanase is water soluble, possesses both C.sub.1, and C.sub.x types of enzyme activity, a high degree of stability toward heat, and exhibits optimum temperature activity at about 81
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Thermal Tolerant Cellulase from Acidothermus Cellulolyticus

The invention provides a thermal tolerant cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as GuxA. GuxA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identifie
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Synthesis of an Acid Addition Salt of Delta-Aminolevulinic Acid from 5-Bromo Levulinic Acid Esters

A process of preparing an acid addition salt of delta-aminolevulinic acid comprising:dissolving a lower alkyl 5-bromolevulinate and an alkali metal diformylamide in an organic solvent selected from the group consisting of acetonitrile, methanol, tetrahydrofuran, 2-methyltetrahydrofuran and methylfor
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Synthesis of Acid Addition Salt of Delta-Aminolevulinic Acid from 5-Bromo Levulinic Acid Esters

A process of preparing an acid addition salt of delta-aminolevulinc acid comprising:a) dissolving a lower alkyl 5-bromolevulinate and hexamethylenetetramine in a solvent selected from the group consisting of water, ethyl acetate, chloroform, acetone, ethanol, tetrahydrofuran and acetonitrile, to for
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Supercritical Separation Process for Complex Organic Mixtures

A process is disclosed for separating low molecular weight components from complex aqueous organic mixtures. The process includes preparing a separation solution of supercritical carbon dioxide with an effective amount of an entrainer to modify the solvation power of the supercritical carbon dioxide
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Sterilization of Fermentation Vessels by Ethanol/Water Mixtures

A method for sterilizing process fermentation vessels with a concentrated alcohol and water mixture integrated in a fuel alcohol or other alcohol production facility. Hot, concentrated alcohol is drawn from a distillation or other purification stage and sprayed into the empty fermentation vessels. T
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