Apr-14-14
A newly developed and highly accurate way of measuring the glucose in urine could give diabetics a break from the daily finger pricks required to draw blood.
Although surface-enhanced Raman scattering (SERS)-based assays are an easy way to measure glucose levels, their sugar receptors usually have a low detection level and cannot differentiate between sugars. This means that samples must often be purified before testing and that the device may not be able to distinguish glucose from other sugars.
The new assay, created by a team from the A*STAR research institute in Singapore, uses triosmium carbonyl conjugates as the sugar receptors and a material developed by the team called bimetallic film over nanospheres (BMFON) to enhance the signal. In tests, the new assay was able to indicate the glucose levels in a small, unpurifed urine sample, and the team believes the technology could be developed for clinical use.
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