Christopher Love

Areas Christopher Love is Knowledgeable in:

Techniques Christopher Love Uses:

Christopher Love's Problem Solving Skills:

1. multivariate analysis & design
2. Highly computer literate (MS Office, SIMCA, MODDE, Spotfire, SciFinder, Reaxsys, chemistry drawing packages, some Oracle, Pipel
3. Synthetic organic chemistry, medicinal chemistry
4. Motivation/leadership of team members

Christopher Love's Problem Solving Experience:

1. Improved communication to senior management by creating flexible, updateable helicopter view of structural plus vitro-to-PK data (12 dimensional).
2. Initiated and led a medicinal chemistry/pharmacology/modelling program to apply multivariate design to explore ligand diversity more efficiently.
3. Took project in two years from high-throughput screening results to late lead optimization. My original analysis withstood repeated challenge, and therefore less valuable series were not pursued
4. Increased potency of a chemical hit by 1000 in two months. Cellular toxicity also resolved.
5. Key synthetic organic chemistry challenge resolved; later implemented on a multi-kilogram scale
6. Learned and implemented the latest thinking on physicochemistry to deliver bioavailability for a chemical series considered very difficult by my superiors.
7. Can routinely resolve issues with (chemical) compound claims on competitor patent portfolios - I am co-inventor as discovery medicinal chemist on 13 patents.
8. Directed an external team of six chemists to execute critical chemistry for a project in lead optimization.