Knut Langsetmo

Knut Langsetmo's Problem Solving Skills:

1. fluorescence spectroscopy
2. static and dynamic light scattering
3. high pH anion exchange chromatography with pulsed amperomeric detection
4. circular dichroism spectroscopy
5. analytical ultracentrifugation
6. differential scanning calorimetry
7. isothermal titration calorimetry
8. biochemistry
9. biophysical analysis
10. surface plasmon resonance
11. mass spectrometry
12. biophysical characterization of proteins
13. cloning, expression, and purification of proteins from bacteria, yeast, insect cells and mammalian cells

Knut Langsetmo's Problem Solving Experience:

1. I developed a method for co-expression of the myosin phosphatase targeting and catalytic subunits, allowing the crystal structure to be determined.
2. I developed a method for expressing recombinant skeletal muscle actin—a feat that had been attempted for 20 years without success.